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Biomedical subjects

S Kadir

Publications and source records attributed to S Kadir.

At least 73 records · Page 4Linked to original sources

Angioarchitecture of pulmonary arteriovenous malformations: an important consideration before embolotherapy.

Seventeen patients with 91 pulmonary arteriovenous malformations were evaluated by superselective angiography. Seventy-two (79%) of the malformations consisted of a simple type characterized by a single feeding artery draining into a bulbous, nonseptated aneurysmal communication with a single draining vein. The other 19 (21%) were complex, consisting of two or more pulmonary artery branches communicating with a bulbous septated aneurysmal part with two or more draining veins. Two patients had diffuse pulmonary arteriovenous malformations confined to multiple lobes of the lung. Balloon embolotherapy was effective in permanently obliterating the malformations in 14 patients treated. Therapy provided a sustained rise in arterial PO2 in the sitting position from a mean value of 44 mm Hg before occlusion to 65 mm Hg after occlusion. In three patients the process was too diffuse and/or the malformations too large for therapy to be effective. Complex pulmonary arteriovenous malformations required occlusion of all feeding arteries. Balloon embolotherapy provided an effective treatment for pulmonary arteriovenous malformations regardless of anatomic type.

Adolescent↗

Long-term results of aortoiliac angioplasty.

Results of percutaneous transluminal angioplasty of 141 iliac arteries in 112 patients are reported, with a follow-up period extending to 36 months. Initial technical success was achieved in 95.7%, 1-year patency in 91.3%, and accumulated 2- and 3-year patency in 89%. The role of outflow disease and ankle:arm index measurement and the importance of eliminating or significantly reducing the intra-arterial pressure gradients are discussed.

Adult↗

Evaluation of arterial injury due to balloon angioplasty by 111In-labelled platelets.

The sensitivity of 111In-labelled platelets for the detection of intimal trauma following balloon angioplasty was evaluated in 8 arteries in 6 patients. Focal platelet accumulation was detected at all 3 iliacs, one superficial femoral and the anterior tibial artery angioplasty sites. Minimal platelet accumulation was present at the superficial femoral artery angioplasty site in another patient whereas in both renal arteries no focal platelet accumulation was detectable. These results indicate that 111In-labelled platelets may provide a sensitive method for evaluation platelet accumulation at the balloon angioplasty site in the peripheral circulation.

Angioplasty, Balloon↗

Pseudo-obstruction of the interior vena cava in pediatric abdominal masses.

Extrinsic compression of the inferior vena cava by large abdominal masses may simulate occlusion on supine cavography. Seventeen children with large abdominal masses were evaluated by inferior venacavography. There was either occlusion or severe compression of the IVC on supine cavography in 13 patients; but the decubitus cavagram and subsequent surgery confirmed patency in 12 patients. In four patients only minor indentations or no abnormalities were present. Pseudo-obstruction of the IVC can be accurately differentiated from occlusion due to invasion by a lateral cavagram in the decubitus position.

Abdominal Neoplasms↗

Embolization of bleeding transverse pancreatic artery aneurysms.

In patients with pancreatitis and blood loss, bleeding from visceral artery aneurysms should be suspected, especially in cases complicated by pseudocyst or abscess formation. We report of a patient with a transverse pancreatic artery aneurysm which was successfully embolized. In addition, decompression of the gastric varices associated with isolated splenic vein occlusion was performed successfully by Gelfoam embolization of 80% of the spleen.

Adult↗

Percutaneous transluminal angioplasty as an adjunct to the surgical management of peripheral vascular disease.

Percutaneous transluminal angioplasty (PTA) was performed as an adjunct to an operation in 43 patients with peripheral arterial insufficiency. This represents 26% of patients undergoing PTA over the past 44 months. In 23 patients PTA was done in conjunction with planned vascular reconstruction. It was successful in all 23 patients, and patency of the vascular graft was maintained in 22 patients during a mean follow-up period of nine months. Fourteen patients had PTA after operation. It was successful in 13 of them, and vascular patency was maintained in all 13 during a mean follow-up period of four months. Six patients had PTA prior to a distal amputation or a skin graft. All healed promptly. The overall initial success rate of PTA was 98%, the complication rate was 2%, with a late failure rate of 2%. It is concluded that PTA is a valuable adjunct to vascular surgery to improve inflow or outflow for bypass grafts, to reduce the extent of the operation in poor risk patients, to facilitate the healing of distal amputations, and to manage late graft stenosis.

Adult↗

Computed tomography of benign hepatic tumors.

Computed tomography (CT) was performed on five patients with focal benign liver lesions: two cases of focal nodular hyperplasia (FNH) and three cases of hepatic adenoma (HA). All five patients had low density lesions seen best on noncontrast scans. Focal nodular hyperplasia often presents as an asymptomatic, well circumscribed lesion with a central, stellate, fibrous scar. Hepatic adenoma, which is associated with the use of oral contraceptives, is a smooth bordered mass that exhibited foci of hemorrhage in two of our three cases. Both of these benign liver lesions enhance to a variable degree of following intravenous contrast medium administration. It is concluded that a specific diagnosis of FNH or HA may be suggested when appropriate CT findings are detected.

Adult↗

Hemodynamic measurements in the evaluation and follow-up of transluminal angioplasty of the iliac and femoral arteries.

Intra-arterial pressure measurements and ankle pressure indices (determined by Doppler ultrasound) were used to evaluate the hemodynamic response after transluminal angioplasty of the iliac and superficial femoral arteries. Intra-arterial pressure was the best determinant of the end point and technical success of the procedure, while improvement in the ankle pressure index was a good predictor of clinical success. Patients with clinical improvement had a significant increase in ankle pressure regardless of the status of peripheral runoff, while those without improvement did not; they demonstrated impaired distal runoff and required further surgical intervention. Peripheral Doppler pressures also provided a convenient noninvasive method of long-term follow-up.

Angioplasty, Balloon↗

Percutaneous biliary drainage in the management of biliary sepsis.

Percutaneous biliary drainage was performed in 18 patients with biliary sepsis due to acute obstructive cholangitis and postoperative complications. Internal drainage could be established in 78% of patients, and 22% were managed on external drainage. Nine patients were managed on long-term internal drainage, six underwent uneventful surgery after successful percutaneous decompression, and three died as a result of septic shock. Percutaneous biliary drainage procedures can be lifesaving in biliary sepsis. Once infection and the hyperbilirubinemia are controlled, rational therapy plans can be formulated on the basis of the anatomy and natural history of the underlying disease.

Aged↗

Pitfalls in the diagnosis of extraadrenal pheochromocytoma.

Precise localization of pheochromocytomas is an essential part of their preoperative management. As a significant number of these tumors may be extraadrenal multiple, or hypovascular, they may not be detected by computerized body tomography (CBT) or arteriography without film subtraction. In seven patients with extraadrenal pheochromocytomas, all tumors were demonstrated by arteriography. In two cases, subtraction films revealed tumors that had not been visualized on the non-subtraction films. CBT, performed in four patients, demonstrated a mass in two but failed to visualized tumors in the other two.

Adolescent↗

Accuracy of angiography in the localization of pheochromocytoma.

An analysis of 20 patients who underwent angiographic localization of pheochromocytoma is presented. The tumors were localized accurately by arteriography in all 20 patients, by excretory urography in 4 of 13 and by computerized body tomography in 3 of 5. Venous sampling and venography were invaluable aids in the localization of pheochromocytomas in patients with postoperatively elevated catecholamine levels, or in the evaluation of recurrence or metastases. The tumors were extra-adrenal in 7 patients, bilateral in 4 and malignant in 5. The majority of these tumors occurred in women.

Adolescent↗