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Biomedical subjects

S K van Velzen

Publications and source records attributed to S K van Velzen.

5 recordsLinked to original sources

The response of the living organism to dead and fixed dead enclosed homologous tissue.

Polyethylene tubes at both ends and with four perforations in the side walls were filled with untreated homologous necrotic muscle tissue or formaldehyde-fixed or glutaraldehyde-fixed homologous necrotic tissue and implanted subcutaneously in rats. The cell reaction in the tissues surrounding the differently filled tubes was examined. It was found that the inflammatory reaction to untreated necrotic homologous tissue was the least severe.

Aldehydes

Short-term tissue reactions to enclosed glutaraldehyde-fixed tissue.

Polyethylene tubes closed at both ends and with four perforations in the sidewalls were filled with glutaraldehyde-fixed isologous tissue and implanted subcutaneously in rats. The cell reaction during the first 12 days in the tissues adjacent to the tubes was histologically examined. The reaction was compared to the reaction around tubes implanted empty. The examination showed a severe inflammatory reaction with probably immunologic aspects in the tissues adjacent to the filled tubes. The reaction around the empty tubes was slight and transient.

Aldehydes

Response of the living organism to dead and fixed dead, enclosed isologous tissue.

Polyethylene tubes closed at both ends and with four perforations in the side walls were filled either with isologous muscle tissue or with formaldehyde-fixed or glutaraldehyde-fixed isologous tissue, and then implanted subcutaneously in rats. As controls, tubes with solutions of the fixatives were implanted. When cell reaction in the tissues surrounding the differently filled tubes was examined, the reaction to untreated necrotic tissue was found to be the least severe.

Aldehydes

Polyethylene tubes as a model for the root canal.

Polyethylene tubes, closed at both ends with casting wax and with four perforations in the middle, were implanted subcutaneously in rats and evaluated as a research model simulating the root canal. As controls, wax bars and unperforated tubes were implanted. Attention was given to the reaction of the tissue surrounding the perforated empty tube, the tissue reaction to polyethylene and casting wax, and to the displacement of the tubes.

Animals