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Biomedical subjects

S Jones

Publications and source records attributed to S Jones.

At least 703 records · Page 39Linked to original sources
PubMedDate not supplied

Creating a flexible learning environment.

Lack of classroom space is a common problem for many hospital-based nurse educators. This article describes how nursing educators in one institution redesigned fixed classroom space into a flexible learning center that accommodates their various programs. Using the nursing process, the educators assessed their needs, planned the learning environment, implemented changes in the interior design, and evaluated the outcome of the project. The result was a learning environment conducive to teaching and learning.

Education, Nursing, Continuing↗
PubMedDate not supplied

Oxygen desaturation is common and clinically underappreciated during elective endoscopic procedures.

This study compared how often oxygen desaturation occurred during conscious sedation for upper and lower procedures, the frequency and extent of desaturation occurring after sedation with diazepam plus meperidine to that occurring after midazolam plus meperidine, and the relationship between age or type of procedure (upper versus lower) with oxygen desaturation to less than 90%. Two-hundred and thirty-six consecutive patients undergoing elective upper or lower endoscopic procedures under conscious sedation had oxygen saturation measured by pulse oximeter before sedation, following sedation but prior to the procedure, and while sedated and undergoing the procedure. Forty-five percent of the subjects desaturated to less than 90% without demonstrating any clinical signs of distress, including 40% of those undergoing upper procedures and 54% of those undergoing lower procedures. Neither the age of the patient, the drugs used, drug doses used, nor the type of procedure accurately predicted which patients would desaturate to less than 90%. Potentially significant oxygen desaturation cannot be reliably predicted by clinical criteria. Pulse oximetry is far more sensitive than standard clinical monitoring practices in detecting oxygen desaturation.

Adult↗
PubMedDate not supplied

Health care in Lesotho.

Explore the source record for details and available documents.

Cross-Cultural Comparison↗
PubMedDate not supplied

Applying nasal intermittent positive pressure ventilation.

This paper looks at the use of nasal intermittent positive pressure ventilation, an intervention which can improve the quality of life for patients who suffer from chronic respiratory failure. The practicalities and management of such patients are described and the benefits.

Humans↗
PubMedDate not supplied

Surgical "touch artefacts" of the cerebral cortex. An experimental study with light and electron microscopic analysis.

In surgically excised brain tissue a very common artefact, unrelated to the presence or absence of a genuine pathological process, involves the water content of cortical neurons. Nerve cells may show massive watery swelling of both their cytoplasm and nuclei or conversely may become shrunken and dark-staining. The most important aspect of this alteration is that it may lead to mistaken histopathological interpretation, but the question also arises whether such changes, presumably caused by exposure, touch, pressure or the combination of all 3, in the living patient, would persist after surgery and would eventually result in irreversible damage to the involved neurons? Thirty rats were operated in this experiment: craniotomy and opening of the dura mater was done over one convexity and slight pressure (uniformly calibrated for all animals) was applied to the exposed cortex. The wound was closed and the animals were sacrificed at various intervals, ranging from immediately after the operation to 6 weeks. The areas that suffered compression were examined by light and electron microscopy. Initial changes included marked watery swelling of neuronal perikarya and nuclei which predominated over pyknotic changes. The changes thus produced were identical with those seen in portions of the cortex excised immediately after pressure was applied to the area in 10 additional rats.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMedDate not supplied

A comparative trial of recombinant interferon alpha 2A versus alpha 2 beta on myelosuppression in healthy adult volunteers.

BACKGROUND/AIMS: Recombinant interferon (r-IFN) is an antiviral agent used to treat patients with chronic viral hepatitis patients. Unfortunately, the use is often limited due to its myelosuppressive properties. Currently, there are two forms of r-IFN commercially available: r-IFN alpha-2a and rIFN alpha-2b. Although both are thought to be equally effective, a comparative study of their myelosuppressive properties has not been undertaken. MATERIALS AND METHODS: In the present study, three groups of healthy adult volunteers (n = 6/group) were randomized to receive a two week course of either r-IFN alpha-2a or r-IFN alpha-2b (5 million units, subcutaneously, thrice weekly) or no treatment. All subjects were then followed for an additional two week post treatment; observation period. RESULTS: The results of the study revealed that both forms of r-IFN alpha caused a significant and similar decrease in white blood cell counts (maximum declines of 37.9 +/- 6.8% for alpha-2a and 39.5 +/- 6.0% for alpha-2b at day 4) and platelet counts (maximum declines of 19.5 +/- 8.6% for alpha-2a and 20.2 +/- 8.4% for alpha-2b at day 2) from baseline values. Following discontinuation of therapy, white blood cell and platelet counts returned to pretreatment levels. Hemoglobin levels remained unchanged throughout the study period. CONCLUSION: The results of this study indicate that r-IFN alpha causes a prompt and significant decrease in white blood cell and platelet counts. However, no differences exist between r-IFN alpha-2a and r-IFN alpha-2b in terms of their myelosuppressive properties in humans.

Adult↗
PubMedDate not supplied

Using health promotion to support volunteer workers.

Volunteers face the same potential stresses and anxiety at work as paid workers, but may not have access to sources of support. This paper describes how one hospice approached meeting the mental health needs of its volunteers

Burnout, Professional↗
PubMedDate not supplied

Changing behaviors. Nurse educators and clinical nurse specialists design a discharge planning program.

In this article, the authors describe a discharge planning program developed for geriatric and maternal-child nurses at Mount Sinai Medical Center. King's theory of goal attainment was used in the program design and teach strategies were selected that matched behavioral objectives in the cognitive, psychomotor, and affective domain. Evaluation methods include participants' pre- and post-surveys regarding their comfort in implementing discharge planning and concurrent review of their documentation 1 month after the program. After participating in the program, staff nurses displayed a change in behavior in terms of increased documentation relating to discharge planning.

Education, Nursing, Continuing↗
PubMedDate not supplied

Send in the clones.

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Animals↗