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Biomedical subjects

S J Wells

Publications and source records attributed to S J Wells.

45 records · Page 3Linked to original sources
PubMed1995

A study of the use of milk replacers for dairy calves in the United States.

This study focused on aspects of the National Dairy Heifer Evaluation Project that involved neonatal feeding practices and types of milk replacers utilized on dairy farms. Types of milk replacers and the management practices associated with their feeding were studied. Nearly 60% of US dairy farms use milk replacers for some or all of the feeding program for neonatal calves. Regional differences existed in the types of liquid feeds and milk replacers fed to calves. Western producers fed less milk replacer, and western and northeast producers fed replacers with less total CP. Many characteristics of management utilized along with these products reflect accepted management and nutrition practices. During the study period from 1991 to 1992, 11.2% of replacers contained casein. A greater proportion of these were found in the West during the first 6 mo of the study, reflecting changes in the milk replacer formulations during that time.

Animal Feed↗
PubMed1995

Effect of long-term administration of a prolonged release formulation of bovine somatotropin (sometribove) on clinical lameness in dairy cows.

A matched case-control study design was used to assess the effects of long-term administration of a prolonged release formulation of bovine somatotropin (sometribove) on clinical lameness and limb lesions in dairy cows. Cows treated with sometribove for at least 2 lactations (cases) and nontreated dairy cows matched by herd, parity, age, and stage of lactation (controls) in 8 herds were evaluated for clinical lameness (as assessed by gait abnormality) and limb lesions by 2 observers, using a standardized scoring procedure at a single herd visit. Although a high proportion of the study cows were clinically lame (43%), an association was not detected between chronic administration of sometribove and prevalent lameness. Of 21 types of limb lesions identified, 2 were positively associated and 2 were negatively associated with long-term sometribove use. Superficial laceration of the tarsus (odds ratio [OR] = 2.1) and superficial swelling of the metatarsophalangeal joint (OR = 4.5) were positively associated with sometribove treatment, whereas femoral lesions (OR = 0.2) and superficial lacerations of the femur (OR = 0.14) were negatively associated with sometribove treatment.

Age Factors↗
PubMed1994

Ability of laboratory methods to predict in-use efficacy of antimicrobial preservatives in an experimental cosmetic.

The abilities of nine antimicrobial systems to preserve an experimental water-based cosmetic formulation were evaluated by six microbiological challenge tests: the U.S. Pharmacopeia test; the British Pharmacopeia test; the Cosmetic, Toiletry, and Fragrance Association test; the rapid screen test; the sequential challenge test; and the post-use test. The antimicrobial systems contained various combinations and amounts of two parabens and a quaternary compound in order to provide a broad range of preservation. The results obtained were compared with the abilities of the formulations to support maintenance and growth of microorganisms in microfloras obtained from human axilla areas and finger skin during an 8-week simulated in-use test. Without statistical analysis all of the tests predicted the results obtained with well-preserved or poorly preserved formulations. The rapid screen test was the best test for predicting differences at intermediate levels of preservation. Statistically, all of the tests were equivalent predictors of preservation efficacy in the in-use test (P = 0.05). At the P = 0.10 level, only the U.S. Pharmacopeia, British Pharmacopeia, rapid screen, Cosmetic, Toiletry, and Fragrance Association tests were significantly predictive. The results of prediction by a test, based on the preservative levels used, agreed well with the in-use test results (P = 0.01). A total of 20% of the formulations that contained excessive microbial levels contained human axilla microorganisms. The levels of preservation in failed products were similar to the levels of preservation in unused controls.

Axilla↗
PubMed1994

The National Dairy Heifer Evaluation Project: a profile of heifer management practices in the United States.

The National Dairy Heifer Evaluation Project was a cooperative, USDA-sponsored project involving state agricultural departments, the Cooperative Extension Service, the National Agricultural Statistics Service, and the Animal and Plant Health Inspection Service. A series of retrospective and prospective descriptive surveys using a multiple list and area frame sampling technique were conducted. Information collected pertained primarily to dairy neonates and replacement heifers. Much of the study was related to observational information on health and management characteristics that can be related to the animals' long-term physical and economic performance. The data reflect herds representing 78% of the national dairy cow population. Average herd size was 86 milking and dry cows and 66 heifers. Many characteristics of these herds reflect accepted and recommended practices in the area of dairy replacement management and nutrition. Data summarized in this national study can be utilized to evaluate the impact of management practices on dairy operations.

Animal Nutritional Physiological Phenomena↗
PubMed1993

Prevalence and severity of lameness in lactating dairy cows in a sample of Minnesota and Wisconsin herds.

An epidemiologic study investigating the prevalence of lameness in lactating dairy cows was performed in 17 dairy herds in Minnesota and Wisconsin. The mean herd size was 50 cows. Cows from 14 herds were housed in stanchions or tie stalls, and cows from 3 herds in free stalls or dry lot. During visits to each farm in the summer and subsequent spring, 2 investigators simultaneously but independently evaluated the ambulation of lactating cows by use of a standardized scoring system. The lameness scoring system was reliable at the 2 visits, with 92.7 and 91.3% agreement between the 2 observers and kappa coefficients of 0.60. The prevalence of lameness detected by the investigators ("clinical" lameness) was 13.7% (117/853) in summer and 16.7% (134/801) in spring in lactating dairy cows. These prevalences were 2.5 times higher than those estimated by the herd managers. Parity was significantly (P < or = 0.03) associated with lameness, with higher prevalence of clinical lameness found in cows of higher parity.

Animals↗
PubMed1993

Alternative sources of hematopoietic stem cells for bone marrow transplantation and rescue.

Hematopoietic stem cells from sources other than medullary bone marrow are being used for experimental and clinical rescue following myeloablative therapy. In this paper we review the cells capable of bone marrow engraftment and the use of orthotopic, cadaveric, peripheral blood, umbilical cord blood, and fetal liver derived stem cells in transplantation.

Blood Cells↗
PubMed1993

Association between clinical lameness and Borrelia burgdorferi antibody in dairy cows.

Results of an ELISA, indirect fluorescent antibody (IFA) test, and immunoblot analysis (western blotting) for antibody to Borrelia burgdorferi in a sample of 216 lactating dairy cows were compared. The microscopic microtitration agglutination test for antibody to 6 serovars of Leptospira interrogans was also performed to evaluate possible cross-reactivity between B burgdorferi and L interrogans. Using western blotting as the standard test against which the ELISA and IFA test were compared, the ELISA had greater sensitivity (50% in summer and 38% in spring) with similar specificity (83 and 82%), compared with the IFA test (sensitivity, 6 and 5%; specificity, 90 and 83%). In addition, seropositivity to B burgdorferi, using the ELISA, was not found to be associated with seropositivity to L interrogans serovars. A matched case-control study evaluating the association between clinical lameness and antibody to B burgdorferi was performed in lactating dairy cows of 17 Minnesota and Wisconsin herds. Sera from case and control cows matched by herd, parity, and stage of lactation were evaluated, using an ELISA for B burgdorferi antibody during 2 seasons. High B burgdorferi antibody values were associated with clinical lameness in dairy cows (P = 0.006 in summer and P = 0.04 in spring).

Animals↗
PubMedDate not supplied

Child protective services: research for the future.

The legal context of child protective services provides the framework for all inquiries and knowledge-building in the field. From this foundation, it is possible to analyze the definition of a child protective services case, describe who is served by the system, evaluate current system functioning, and identify outcome measures. Future research should address formative questions such as the development of consistent definitions of maltreatment and evaluation of service delivery. Evaluation should include measuring treatment outcomes as well as examining the functioning and management of the system.

Child↗