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Biomedical subjects

S J Schaberg

Publications and source records attributed to S J Schaberg.

At least 19 recordsLinked to original sources
PubMed1998

Oropharyngeal mass.

Explore the source record for details and available documents.

Acquired Immunodeficiency Syndrome↗
PubMed1987

Multiple radiolucent areas of the jaw.

A case of neurofibromatosis, or von Recklinghausen's disease, was presented. The skin manifestations include the development of numerous, variable sized, smooth-surfaced nodules (benign neural tumors) and asymmetric areas of hyperpigmentation called cafe-au-lait spots. Oral manifestations are not always apparent but, when they do occur, include multiple, discrete, nonulcerated mucosal nodules (typically benign neural tumors). Intraosseous tumors (usually neurofibromas) occasionally develop in the mandible as was reported in this patient. Clinicians should be aware of the characteristics of this hereditary disease, especially the possibility of malignant transformation of the neural tumors.

Adolescent↗
PubMed1985

A comparison of freeze-dried allogeneic and fresh autologous vascularized rib grafts in dog radial discontinuity defects.

The limitations of autologous vascularized grafts include morbidity at the donor site and the increased surgical time associated with graft retrieval. To overcome these limitations, freeze-dried allogeneic and fresh autologous vascularized rib grafts were compared in 6-cm mid-radial defects of dogs. There was no statistically significant difference between the two graft systems when postoperative radiographs, in vivo intraarterial angiograms, and histologic evaluation of vessel patency were compared. However, clinical assessment of graft stability favored the autologous grafts, and force deflection tests revealed that the freeze-dried grafts had only 64% of the graft strength of the fresh autologous grafts at the end of the experiment at 26 weeks.

Angiography↗
PubMed1985

Enzyme-linked immunosorbent assay for detection of antibodies to Staphylococcus aureus cell walls in experimental osteomyelitis.

An enzyme-linked immunosorbent assay was used to evaluate and compare the immunoglobulin G antibody response to Staphylococcus aureus cell walls of rabbits with either chronic staphylococcal osteomyelitis or subcutaneous abscesses. Osteomyelitis of the femur was produced by the intramedullary application of a sclerosing agent (3% sodium tetradecyl sulfate) and S. aureus. Radiographic evidence of osteomyelitis was observed in 10 of the 13 animals that survived the 10-week experimental period, and the diagnosis was confirmed by histopathology in 8 of the 10 instances. Abscess formation was initiated in a separate group of rabbits by the subcutaneous injection of S. aureus cells. All 10 of these rabbits subsequently developed abscesses, which usually resolved spontaneously within 3 to 5 weeks. Elevated levels of immunoglobulin G antibodies to the cell wall antigen were detected in 7 of 10 rabbits with osteomyelitis at 21 days postinfection, and these animals continued to display high antibody levels even at 59 days postinfection. In contrast, elevated levels of anti-cell-wall antibodies were only detected in 1 of 10 rabbits with subcutaneous abscesses. The enzyme-linked immunosorbent assay was found to be a rapid and sensitive serological technique for the detection of cell wall antibodies in this experimental osteomyelitis model and may be useful for the diagnosis of staphylococcal bone infections in humans.

Abscess↗
PubMed1984

The effects of antibiotic-supplemented bone allografts on contaminated, partially avulsive fractures of the canine ulna.

The use of antibiotic-supplemented bone allograft as a material for placement in contaminated fractures of the dog ulna was investigated. Demineralized, freeze-dried bone allografts mixed with antibiotics and gelatin were placed in five fractures contaminated with Staphylococcus aureus (Washington Hospital strain) and Pseudomonas aeruginosa (PA 220). The results of treatment with antibiotic-supplemented bone allografts were compared with the results of conventional treatment in five additional experimental animals in which fractures contaminated with S. aureus and P. aeruginosa were created. The five fractures treated by conventional methods developed acute osteomyelitis and nonunion, whereas the ASBA-treated fractures resulted in bone union without infection. ASBA-treated fractures were stable and had 89% of the shearing strength of the non-fractured, contralateral ulnae five months after treatment.

Animals↗
PubMed1984

Effect of methylprednisolone on swelling after orthognathic surgery.

The effectiveness of methylprednisolone for the reduction of postoperative facial edema was evaluated by the computed tomographic examination of 39 patients who underwent either a Lefort I osteotomy or a transoral vertical osteotomy. Results of the CT scans, which were performed preoperatively and at 24 and 72 hours postoperatively, showed that in the LeFort I osteotomy patients methylprednisolone reduced the degree of facial edema by 61% at 24 hours postoperatively and by 10% at 72 hours. In the transoral vertical osteotomy patients methylprednisolone reduced the degree of facial edema by 38% at 24 hours postoperatively and by 45% at 72 hours. It was concluded that methylprednisolone is effective for the control and management of postoperative facial edema following orthognathic surgery.

Adolescent↗
PubMed1984

Garre's osteomyelitis of the mandible resolved by endodontic treatment.

A case of Garre's osteomyelitis of the mandible is presented. The occlusal radiographs are good examples of the redundant cortical layering of the bone (onion skinning) that is classically found with this phenomenon. The cause of this case was a necrotic pulp in a carious molar with a periapical radiolucent area. We believe this is the first reported case in which an odontogenic source of infection (carious tooth) was treated not by extraction but by endodontic therapy. During the year after the root canal filling, the periapical radiolucent area filled in with new bone and the bony expansion of the mandible was completely resolved.

Child↗
PubMed1983

Use of the segmented LeFort I osteotomy to correct severe extrusion of maxillary posterior teeth or tuberosities.

The segmented LeFort I osteotomy technique is presented as a surgical alternative for the correction of severe posterior maxillary vertical excess prior to prosthodontic procedures. It allows the extruded maxillary dento-osseous segment to be retained and a normal plane of occlusion to be reestablished. The superior visibility, accessibility, and versatility afforded by the segmented LeFort I osteotomy technique make it particularly suited to the correction of severe posterior maxillary excess.

Adult↗