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Biomedical subjects

S J Rowbottom

Publications and source records attributed to S J Rowbottom.

27 records · Page 2Linked to original sources
PubMed1990

Oral ketamine premedication for paediatric cardiac surgery--a comparison with intramuscular morphine (both after oral trimeprazine).

In a single-blind controlled study, forty children with congenital heart disease were premedicated with oral trimeprazine 3 mg/kg and either intramuscular morphine 0.1 mg/kg or oral ketamine 10 mg/kg. Cardiovascular and respiratory effects of premedication and degree of sedation induced were similar in the two groups of patients. Oral ketamine is a safe and effective premedicant in this group of patients.

Administration, Oral↗
PubMed1989

Isoflurane for thymectomy in myasthenia gravis.

The clinical and electromyographic effects of isoflurane were studied in eight myasthenic patients undergoing trans-sternal thymectomy. After inhalational induction of anaesthesia, intubating and operating conditions were good. Recovery from anaesthesia was rapid with minimal postoperative residual muscle weakness or respiratory depression. All patients were extubated within the first postoperative hour. Integrated electromyographic monitoring of the train-of-four response of adductor pollicis demonstrated that myasthenics are more sensitive than nonmyasthenics to the neuromuscular depressant effects of isoflurane. Recovery of the integrated electromyographic response was incomplete despite a satisfactory clinical recovery.

Adolescent↗
PubMed1988

Haemoglobin H disease and cardiac surgery.

The management of two patients with haemoglobin H disease, who underwent open-heart surgery, is described and the problems that relate to anaesthesia in the presence of this condition are discussed.

Adult↗