Pseudomembranous colitis following prophylactic antibiotics in bowel surgery.
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Biomedical subjects
Publications and source records attributed to S J Powis.
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Experience with whole-gut irrigation as a method of bowel preparation in eightyone patients is described. The mean (+/-S.D.) weight-gain during irrigation was 1-9 +/- 0-8 kg; potassium losses in the effluent after one hour (4-0 +/- 2-5 g) were not significantly altered by adding potassium chloride to the irrigant. Eight irrigations were unsatisfactory, three being due to unrecognised obstructive neoplasms. The method provided excellent preparation for colonoscopy and large-bowel resection with anastomosis and was well tolerated by the patients.
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A retrospective survey was made of 305 patients with proved urinary calculi. When those patients with a solitary stone were compared with those with multiple stones no diagnostically helpful difference was noted in the prevalence of abnormal serum or urine biochemistry, urinary infection, or anatomical abnormality of the urinary tract. The same was true of the stone composition and the need for surgery. It seems that neither routine radiological examination nor regular follow-up is likely to help identify patients whose stones are going to recur.
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A retrospective survey of 4,026 patients having truncal vagotomy and pyloroplasty for duodenal ulceration showed a mortality rate of 1.4% (55 patients). On analysis the commonest causes of death were found to be bronchopneumonia 37% (18 patients) and sepsis 20% (10 patients). More than half of the deaths occurred in patients aged over 50.
Fatal colonic complications in five patients after cadaveric renal transplantation were all due to ischaemia of the bowel wall, which in two cases had led to multiple perforation. In two the lesions involved the whole colon and in three they were segmental.
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Achilles tenotomy was performed on 66 limbs in 60 patients with severe intermittent claudication and the results were assessed two years later. Early improvement occurred in half of them but decreased to 17% two years postoperatively. Sympathectomy did not influence the result. The postoperative morbidity was 14%, and 21% of limbs were subsequently amputated. The late mortality in the group studied was 8%.
The uretero-vesical junction has been examined by micturating cystography in 20 patients after renal transplantation. Intravenous pyelograms were used to investigate the upper urinary tract in 13 of the patients. Persistent urinary infection did not occur in patients without vesico-ureteric reflux. However, both those with reflux of their own and the transplant ureters had persistent infection. When reflux affected the tunnelled transplanted ureter there was no infection, but two patients without a tunnel implant had a persistent urinary infection.
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