Student interest in a protocol-based system for self-care decision making.
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Arizona↗
Biomedical subjects
S J Coons
Publications and source records attributed to S J Coons.
The role of colleges of pharmacy in meeting the pharmacoeconomic needs of the pharmaceutical industry: a conference report.
To provide a forum for the exchange of ideas regarding the role of colleges of pharmacy in meeting the pharmaceutical industry's pharmacoeconomic needs, an invitational conference was conducted by the University of Arizona's Center for Pharmaceutical Economics on January 14 and 15, 1993, in Tucson, Arizona. This article represents the program design, program types, and consensus development portions of that conference. A description of current needs in pharmacoeconomics was obtained through transcripts of industry and university presentations, panel discussions, and question-and-answer sessions. Conference participants generally agreed that pharmacoeconomics holds great potential for making significant contributions to health care but that it will not flourish without deliberate and cooperative efforts. Participants from both industry and academia voiced the need for the two parties to work together to increase the visibility and understanding of pharmacoeconomics and to meet the training and staffing challenges facing the discipline.
Drug Industry↗
Selective serotonin reuptake inhibitor dose titration in the naturalistic setting.
Little information exists regarding the use of selective serotonin reuptake inhibitors (SSRIs) in the naturalistic setting. The Regenstrief Medical Record System was used to analyze the dosing of SSRIs in the outpatient population of an urban teaching hospital. A cohort of 3350 patients was extracted, of whom 2859 had received fluoxetine and 460 sertraline. This cohort received 21,079 prescriptions. (The 31 patients who were prescribed paroxetine were eliminated from further analysis.) The mean daily dose for all patients receiving fluoxetine was 21 +/- 6 mg for the first prescription dispensed and 25 +/- 11 mg for the ninth. For fluoxetine-treated patients with depression included on their computerized medical problem list, the mean daily dose was 21 +/- 6 mg for the first prescription and 26 +/- 12 mg for the ninth. A mean of 5.0% of all patients continuing fluoxetine therapy had their daily dose increased with each prescription refill during the first nine prescriptions. The mean daily dose for all patients receiving sertraline was 59 +/- 28 mg for the first prescription and 117 +/- 66 mg for the ninth. For sertraline-treated patients with depression included on their computerized medical problem list, the mean daily dose was 57 +/- 25 mg for the first prescription and 110 +/- 65 mg for the ninth. A mean of 14.9% of all patients continuing sertraline therapy had their daily dose increased with each prescription refill during the first nine prescriptions. The frequency of sertraline dose increases was 2 to 3 times the rate for fluoxetine. Because increases in daily doses typically result from inadequate control of symptoms of depression, these findings may reflect fluoxetine's greater effectiveness in controlling symptoms during the initial stages of therapy in the naturalistic setting.
1-Naphthylamine↗
Predictors of medication noncompliance in a sample of older adults.
The subjects were 1028 respondents from a randomly selected sample of independently living adults aged 55 years and older in the southeastern United States. Data on background characteristics, physical health, life satisfaction, psychological distress, and medication compliance were gathered from structured interviews. Among the 785 subjects in the analysis who were taking prescribed medications, 75% were women, 83% were white, their median income was $12,500 annually, 66% lived alone, their mean age was 73.9 years, and their mean number of years of education was 11.4. Twenty-one percent of all respondents taking medications had been noncompliant during the month preceding the study interview. Noncompliance with prescribed medications was significantly associated with higher socioeconomic status (P < 0.01), greater number of prescribed medications (P < 0.01), and higher psychological stress (P < 0.05). There was no relationship between compliance and living arrangements, health, life satisfaction, number of illnesses, age, or sex.
Aged↗