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Biomedical subjects

S Iu Tursunov

Publications and source records attributed to S Iu Tursunov.

11 recordsLinked to original sources
PubMed1989

[Secondary prophylaxis of arterial hypertension among an unorganized rural population and the means for increasing its effectiveness].

The program of arterial hypertension control has been implemented for 3 years among the nonorganized community in two rural districts of Andizhan Province of the Uzbek SSR. Of these, one was a district of intervention and the other one a reference district. It may be concluded as a result that awareness of the patients that they are afflicted with arterial hypertension rose from 40.4 to 83%, the treatment coverage from 19.4 to 66.8%, and the number of patients with favourable treatment results from 4 to 36.6%. During the 3 years, the total death rate, the mortality due to cardiovascular disease, myocardial infarction and brain stroke appeared statistically less significant in the district of intervention as compared to the reference district. For successful prevention of arterial hypertension among the rural community it is necessary that paramedical personnel may be engaged in such activities on an ever increasing scale.

Adolescent↗
PubMed1985

[Ischemic heart disease and its relation to basic risk factors among the rural population].

Using standard methods of the epidemiological survey the authors examined a 10% randomized sample of men aged 40 to 59 years living in a rural area. A total of 533 persons were entered into the study (a 82% coverage). Based on the epidemiological data the coronary heart disease (CHD) prevalence was established to amount to 8.8% according to the enlarged criteria (angina pectoris of effort according to the WHO cardiological questionnaire; the definite myocardial infarction with the Minnesota code categories 1.1-1,2.7; the painless pattern of CHD with categories 4.1-4.2 and 5.1-5.2 without 3.1 and 3.3; possible myocardial infarction 1.2.8, 1.3; possible myocardial ischemia 4.3, 5.3; the arrhythmic pattern 6.1, 7.1, 8.3; myocardial ischemia with left ventricle hypertrophy 4.1-4.2, 5.1-5.2 with 3.1, 3.3; possible myocardial infarction in the anamnesis in accordance with the WHO cardiological questionnaire). It was also found that in persons aged 50 to 59 years, CHD occurs 2 times as frequently as in those aged 40 to 49 years (13.1 and 5.8%, respectively). The prevalence of CHD was discovered to be about 3.5 times higher in the presence of arterial hypertension and overweight and 2 to 2.5 times higher in the presence of hypercholesterolemia, hypo-alpha-cholesterolemia and hypertriglyceridemia. A high correlation was noted between arterial hypertension and overweight and the prevalence of CHD before (r = 0.174 and r = 0.198, respectively) and after elimination of risk factors (r = 0.14 and r = 0.14). Among CHD patients, one risk factor was noted in 21.8%, two in 39.1%, three and more in 23.9%, whereas among persons without CHD in 32.4, 10.9 and 3.5%, respectively.

Adult↗
PubMed1985

[Arterial blood pressure levels of adolescents and their parents in a rural district (an epidemiological study)].

A 10% randomized sample of adolescents aged 15 to 17 years living in a rural area were examined by standard methods of the epidemiological survey. Altogether 497 boys and 613 girls (a 93.3% coverage) and their parents (1000 fathers and 1053 mothers) were entered into the study. Based on the population-familial material it was established that under rural conditions the mean parameters of the SBP in girls aged 15 years were significantly higher (113 +/- 0.43) than in boys (110 +/- 0.58) (P less than 0.05). At the same time the mean values of the DBP in boys and girls aged 15 to 17 years did not differ substantially, being respectively 69.3, 70.3, 71.5 in boys and 70.6, 70.5, 71.9 in girls. Positive correlations between the SBP and DBP were obtained, ranging from 0.52 to 0.72 in the subgroups of schoolchildren differing in sex and age. Significant correlations were discovered between parents and children: 0.133 +/- 0.022 as regards the SBP; 0.224 +/- 0.021 as regards the DBP; 0.154 +/- 0.054 as regards the SBP and DBP. The ratio of the genetic correlation between the SBP and DBP amounted to 0.89 +/- 0.12, which points to the presence of the essential generality of the genetic determination of both these parameters.

Adolescent↗
PubMed1980

[Genetic analysis of the structure of the predisposition to ischemic heart disease].

Clinical and ECG examination of 752 male population samples (598 Uzbeks and 154 Russians) aged from 40 to 74 conducted according to the WHO criteria showed the incidence of ischemic heart disease among males 40 to 59 years of age to be 10.7% for Uzbeks and 15.1% for Russians (p greater than 0.3) and among males aged from 60 to 74, 16.8 and 19.7%, respectively. The incidence of ischemic heart disease was lower among brothers of male probands 40 to 74 years of age (33.9%) than among brothers of female probands (38.9%); the incidence of this disease was lower among sisters of male probands (23.1%) than among sisters of female probands (30.2%). A similar peculiarity of ischemic heart disease distribution among siblings according to the sex of their probands was found in the 40- to 59-year-old group. This indicates the existence of two thresholds which determine ischemic heart disease prevalence among the different sexes of the population. The incidence of ischemic heart disease among the spouses of the probands aged from 40 to 74 is also higher than that among the population in general; it was 17% on the average, 14.3% among female spouses and 22% among male spouses. The genetic component of ischemic heart disease determination (heritability) was approximately 60%, the intrafamilial one was approximately 20--30%. Thus, besides the genetic factors which determine the liability to ischemic heart disease, there are intrafamilial factors which have an essential effect and which also cause familial aggregation of the disease.

Adult↗
PubMed1979

[Characteristics of the course of ischemic heart disease in thyroid hypofunction].

The peculiarities of lipid metabolism and hyperlipoproteinemia, blood coagulation and myocardial contractility in normal and reduced thyroid function were studied in 162 patients with ischemic heart disease. It was shown that hyperlipoproteinemia, hypercoagulation, and myocardial hypodynamia are revealed more frequently and at earlier periods in hypofunction.

Aged↗
PubMedDate not supplied

[Thyroid dysfunction and diabetes mellitus].

The degree of the thyroid dysfunction was determined in 100 women, suffering from endemic goiter, on the basis of the clinical pattern metabolic findings, the degree of 131I absorption by the thyroid and 131I-labelled thyroxine -- F-factor. The glucose tolerance test (GTT) was performed. In patients with euthyrosis and thyrotoxicosis the insular apparatus response to hyperglycemia was not sufficient. In 31% of the patients GTT was decreased. Latent diabetes mellitus was seen in 17% of the subjects and an evident from the disease in 10%. The thyroid dysfunction in the region of endemic goiter may be responsible for the diabetes mellitus development. The significance of this factor increases depending on thyrotoxicosis intensity.

Adult↗