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Biomedical subjects

S Irwin

Publications and source records attributed to S Irwin.

48 records · Page 3Linked to original sources

Chromosomal abnormalities in leukocytes from LSD-25 users.

A significant increase of chromosomal abnormalities was found in leukocytes from LSD-25 users (six out of eight) compared to nonuser controls (one out of nine). The two LSD-25 users showing no damage reported the lowest estimated average dose. The subjects whose cells showed damage were tested between 1 day and 6 months after their last LSD-25 dose.

Chromosome Aberrations↗

Pentylenetetrazol enhances memory function.

Pentylenetetrazol, in oral doses of 1 to 30 milligrams per kilogram of body weight, significantly facilitated one-trial learning and memory retention in CF1 mice, whether administered before or immediately after the initial trial. The effects appeared significantly greater than those observed in earlier studies with oral administration of strychnine or picrotoxin at 0.2 to 0.8 and 2.4 milligrams per kilogram, respectively.

Animals↗