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Biomedical subjects

S Hyndman

Publications and source records attributed to S Hyndman.

6 recordsLinked to original sources

An epidemiological study of the relative importance of damp housing in relation to adult health.

STUDY OBJECTIVE: To examine the association between damp housing and adult health, taking into account a wide range of other factors that may influence health and could confound this relation. PARTICIPANTS AND SETTING: A general population sample of adults, aged 18-64, from Oxfordshire, Buckinghamshire, Berkshire and Northamptonshire. DESIGN: Secondary analysis of responses to a postal questionnaire survey carried out in 1997 with a 64% response rate (8889 of 13 800). Housing dampness was assessed by self report. Health was measured by responses to a series of questions including presence of asthma and longstanding illness generally, use of health services and perceived health status (the SF-36). The effect of damp was examined using the chi(2) test and one way analysis of variance. Significant associations with the various health outcomes were further explored taking into account 35 other housing, demographic, psychosocial and lifestyle variables using stepwise logistic and linear regression. MAIN RESULTS: Bivariate analyses indicated that damp was associated with the majority of health outcomes. Regression modelling however, found that being unable to keep the home warm enough in winter was a more important explanatory variable. Worry about pressure at work and to a lesser extent about money, showed an independent association with perceived health status equal to or greater than that of the housing environment, including cold housing, and that of health related lifestyles. CONCLUSIONS: This study shows that being unable to keep the home warm enough in winter is more strongly associated with health outcomes than is damp housing. However, as cold and damp housing are closely related, it is likely that their combined effects are shown in these results. The importance of worry as an independent predictor of health status needs testing in other studies. Its prevalence and relative importance suggest that it may be a significant determinant of public health.

Adolescent↗

Sex differences in the use of asthma drugs: cross sectional study.

OBJECTIVES: To assess the use of asthma drugs by men and women with asthma and to identify sex specific predictors for the use of oral steroids. DESIGN: Cross sectional study. SETTING: Six general practices in East Anglia. SUBJECTS: 103 men and 134 women aged 20-54 with asthma. MAIN OUTCOME MEASURES: Self reported use of agonists, inhaled steroids, and oral steroids. RESULTS: No sex difference was found in use of agonists or inhaled steroids. However a strong association existed between sex and oral steroid use. 40 (30%) women reported using oral steroids compared with nine (9%) men. Women were more than five times (odds ratio=5.5, 95% confidence interval 2.2 to 13.7) more likely to report use of oral steroids than men after asthma symptoms, age, visits to the general practitioner in previous six months, and time since diagnosis of asthma were controlled for. Women who had visited the general practitioner for asthma one or more times in the previous six months were four times (3.9, 1.6 to 9.5) as likely to report use of oral steroids. In addition, more frequent visits to the general practitioner for asthma were related in a dose-response manner to a greater likelihood of using oral steroids among women after asthma symptoms, age, and time since diagnosis were controlled for. This relation was not observed among men. CONCLUSION: Women used oral steroids more than men. The more frequent consultations with a doctor by women may result in more requests for oral steroids or doctors may preferentially prescribe oral steroids to women.

Adrenergic beta-Antagonists↗

The association of nocturnal asthma with asthma severity.

The objective of this study is to assess nocturnal asthma as a marker for poor control of asthma. Cross-sectional study of asthmatic patients was conducted in six general practices in East Anglia, England. Subjects were 240 asthma patients, between the ages of 20 and 54 years, from the above general practices. A continuous asthma severity score (range 6-26), consisting of the summation of ordinal responses to questions regarding asthma symptoms during the last 6 months, was used for analysis. The crude association between nocturnal asthma and severity score was statistically highly significant. Regression analysis suggests that, after controlling for possible confounding variables, there remains a strong association between nocturnal asthma (NA) and severity, which is modified by self-report of current consultation for "nervous/emotional trouble" (current NT). In the absence of current NT, NA raises the severity score by 5.3 (95% CI 4.5, 6.2), whereas in the presence of current NT, NA raises the severity score by 8.2 (95% CI 4.8, 11.6). NA appears promising as a marker for poorly controlled asthma. Confirmation of the association found in this study by objective measures of severity would strengthen the utility of NA as a marker.

Adult↗

Criteria formulation and application: an evaluative framework.

This paper critically examines how criteria are formulated and applied in quality assurance or quality improvement systems. It begins by drawing attention to the division that exists between criteria derived by so-called expert groups and those developed more locally by practitioners. In seeking to analyse the strengths and weaknesses of these two contrasting approaches, it explores the more fundamental questions of how criteria are formulated in general and how they can best be applied. An evaluative framework is offered as a working checklist for practitioners involved in criteria formulation. The framework identifies three main areas: actual construction of criteria; procedures for formulation and issues related to application. An example of each area is offered from results of the ODySSSy Project. The paper concludes by recommending more systematic studies in this highly complex area.

Delphi Technique↗

A comparison of expert- and practitioner-derived criteria for post-operative pain management.

A comparison of two methods of criteria formulation was carried out as part of a 3-year research study looking at the effectiveness of a nursing quality assurance system (the Royal College of Nursing's Dynamic Standard Setting System). In particular, the study wished to explore whether and to what extent criteria sets derived from an expert group differed from criteria generated by local practitioner groups. One expert group and five local groups were helped to develop criteria on the topic of post-operative pain management. Results showed that the expert group underwent a much more controlled and systematic approach to the task than any of the local groups who were supported by newly trained facilitators. Despite this difference, two of the five local groups had criteria convergence scores of more than 55%, demonstrating that the local knowledge on the topic was acceptable. Whether the lower convergence of the groups was due to lack of knowledge or a combination of difficult group processes and novice facilitation is difficult to say. However, what the study did show was that local groups can generate criteria sets comparable to expert groups, given proper facilitation and support.

Adult↗