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Biomedical subjects

S Hudson

Publications and source records attributed to S Hudson.

86 records · Page 5Linked to original sources
PubMed1979

Carcinoembryonic antigen in carcinoma of the uterine cervix. 2. Tissue localization and correlation with plasma antigen concentration.

Immunoperoxidase staining for carcinoembryonic antigen (CEA) was performed on the tumors of 241 patients with invasive carcinoma of the cervix. Positive tissue staining indicative of a CEA concentration of at least 3 microgram/gm was present in 154 tumors (63%) as opposed to 0 of 30 specimens of normal cervix (p less than .001). Plasma CEA values were obtained at the time of tissue staining on all patients. Plasma CEA concentration was related more directly to total tumor burden (tumor CEA content x extent of disease) than to tumor CEA concentration alone. Progressively rising plasma CEA levels predicted recurrent disease in over 80% of patients whose tumors stained positively for CEA. In contrast, serial plasma CEA values correlated positively with clinical disease status in only 28% of patients whose tumors were devoid of CEA. Immunoperoxidase staining of tissue specimens identifies those patients whose tumors contain high levels of CEA and who therefore should benefit most from subsequent plasma antigen determinations.

Adenocarcinoma↗
PubMed1976

Bovine plasma corticoids during parturition.

Concentrations of adrenal corticoids in plasma were determined by a competitive protein-binding technique using jugular blood samples taken three times daily and more frequently during labor from 21 cows before and after parturition. The prepartum value was 6 ng/ml with a sharp rise during the last 16 h before calving. The average value at the time of calving was 19.2 ng/ml with a significant drop 1 h after calving to 11.2 ng/ml and a return to basal concentrations by 3 days postpartum. Evidence that labor is responsible for the increased corticoid is given. Maternal cortisol at calving was correlated with the time taken to calve .23, calf cortisol .04, cow:calf weight ratio -.07, and calf weight .14.

Animals↗
PubMed1975

Diurnal variations in blood cortisol in the dairy cow.

Concentrations of adrenal corticosteroids in plasma were determined by a competitive protein-binding technique in blood samples taken hourly over 24 h from four dairy cows, each sampled for three 24 h periods. Mean blood cortisol was 7.9 ng/ml. Statistical analysis revealed no diurnal variation. Reasons for this are postulated.

Animals↗
PubMedDate not supplied

Evaluation of right ventricular volume and ejection fraction in children by two-dimensional echocardiography.

We estimated right ventricular volume and ejection by two-dimensional echocardiography (2DE) and compared the measurements with those obtained by right ventricular cineangiography (ANGIO) in 20 children whose ages ranged from 1 month to 10 years and who had a variety of congenital defects. The two echocardiographic planes used for calculating volume were the apical four-chamber (A4C) and parasternal short-axis (SA) planes. End diastolic volume (EDV) and end systolic volume (ESV) were calculated from these planes by single-plane area-length methods. The EDV and ESV were uniformly underestimated, but the estimate of ejection fraction (EF) was satisfactory. For EF, r = 0.83 from the apical four-chamber view and r = 0.78 from the short-axis view. The axes of the two echocardiographic planes passed through different segments of the right ventricle (RV) and we found that the value given by adding the volumes obtained from the two single-plane segments correlated quite well with the value obtained by angiography: for EDV, 2DE = 0.62 ANGIO + 7.0, r = 0.81, standard error of the estimate (s.e.e.) = 15.4 ml; for ESV, 2DE = 0.82 ANGIO + 1.4, r = 0.85, s.e.e. = 6.5 ml; and for EF, 2DE = 0.66 ANGIO + 17.8, r = 0.82, s.e.e. = 7.4 ml. Two-dimensional echocardiography can be used to evaluate right ventricular EF derived from volume measurements or from each of the echocardiographic planes of which, in our series, the apical four-chamber EF provided the better correlation.

Cardiac Output↗
PubMedDate not supplied

Lock-ring for Tenckhoff catheter/titanium adaptor junction.

One standard continuous ambulatory peritoneal dialysis (CAPD) infusion/drainage system was found prone to recurrent mechanical failure at the junction between the silastic catheter and the titanium connector. This resulted in slackening and eventual disconnection with attendant risk of bacterial entry and a CAPD-associated peritonitis. A simple "lock-ring" device, when fitted over the catheter-titanium connector junction, afforded a secure joint.

Equipment Failure↗
PubMedDate not supplied

Equity in the diagnosis of chest pain: race and gender.

OBJECTIVE: To explore gender and racial equity in emergency room treatment of chest pain. METHODS: Three hundred seventy-nine patient records were analyzed, taking into account effects of age, clinic, comorbid status, and insurance status. RESULTS: Analysis of covariance and logistic regression revealed statistically significant differences between races but not between genders for time to first EKG and percent of patients receiving cardiac catheterization and echocardiography. Blacks waited longer than whites for an EKG and were less likely to receive cardiac catheterizations but more likely to receive echocardiography. CONCLUSION: This study demonstrates a lack of equity by race in treatment of chest pain emergencies.

Adult↗
PubMedDate not supplied

Care of the patient with oesophageal varices.

Practice profiles are reflective pieces written by nurses in practice and based on continuing professional development articles. This week Suzanne Hudson discusses Oesopahgeal varices. CPD article NS 17. McArdle J (1999) Understanding oesophageal varices.

Esophageal and Gastric Varices↗
PubMedDate not supplied

Peer assistance.

Explore the source record for details and available documents.

Confidentiality↗