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Biomedical subjects

S Haque

Publications and source records attributed to S Haque.

81 records · Page 5Linked to original sources
PubMed1981

Stool findings in "chronic dysentery".

Faecal samples from 63 subjects with self-diagnosis of "chronic dysentery" and 50 control subjects were examined under light microscope. Vegetative form of E.h. was not detected in any of them. E.h. cyst was found in 6.3% of the "chronic dysentery" subjects and in 16% of the control subjects. E. coli and Giardia were also detected less often in the "chronic dysentery" than the control subjects. Lower incidence of protozoa namely E.h. cyst, E. coli cyst or Giardia in the former group was probably due to frequent intake of antiamoebic agents which are also effective against other intestinal protozoa. Incidence of Ascaris, hookworm, and Trichuris was not appreciably different in the two groups. More subjects in the "chronic dysentery" group had normal stool findings (31%) as compared to the control subjects (16%). It has been inferred that E.h. infection is not the cause of symptoms of "chronic dysentery".

Adult↗
PubMed1980

Long-term function of NCGT vascular conduits in a multicenter trial: evaluation of physical chemical parameters.

Our experience with the NCGT graft has now encompassed 12 years in experimental animals and 4.5 years clinical experience with 134 grafts in man. It has previously been suggested that vessel wall structure, interface-charge, electric potential, and polarity of the blood intimal interface appear critical in the prevention of intravascular thrombosis in all vascular prosthetic bypass grafts. This concept has now been confirmed using ferritin, colloidal iron and fluorescamine intimal labelling. These provide a quantitative special characterization of the surface charges of several grafts, including the NCGT graft. Study indicates that each step in the production of the NCGT graft results in a cumulative increase in the structured negative charge of the vascular interface. The more dense the structured negative charge of the prosthesis, the more resistant is the graft to short and long-term thrombosis in experimental animals and man. The experience has been confirmed with a comparative analysis of implantation results in 105 patients up to 4.5 years with 65 to 70% patency rate over that time interval. Statistical analysis of parameters confirm again that the polarity and structure of the vascular interface is important in the effective function and patency rate of the grafts.

Animals↗
PubMedDate not supplied

Weight loss in adults with Down syndrome and with dementia in Alzheimer's disease.

An association between weight loss and Alzheimer's disease has been established in the general population but little information is available regarding this association in people with intellectual disabilities. A 4-year longitudinal study of adults with Down syndrome with and without Alzheimer's disease was undertaken. Age-associated weight loss was seen in virtually all older adults with Down syndrome. A significant association between weight loss and Alzheimer's disease was found for older adults with Down syndrome. This study highlights important research and clinical issues regarding weight loss and nutrition in Down syndrome adults with dementia.

Adult↗
PubMedDate not supplied

Pancreatic polypeptide islet cell tumor: case report and review of the literature.

Pure pancreatic polypeptide-containing tumors (PPomas) are quite rare. Only 20 cases have been described. In this article we report a 75-year-old woman with such an endocrine islet cell tumor. The patient had no specific symptoms that could be ascribed to the tumor. An abdominal CT scan revealed a 3 cm soft tissue mass arising inferiorly from the tail of the pancreas. Local resection by way of a distal pancreatectomy was performed. A well-circumscribed hemorrhagic multiloculated mass, 3.7 cm in greatest dimension, was present in the tail of the pancreas. The patient has remained well and tumor free for the past 22 months. The endocrine characterization of the tumor was achieved by means of immunohistochemical analysis. Staining specific for insulin, glucagon, somatostatin, and gastrin was negative. In contrast, staining of the tumor for pancreatic polypeptide was strongly positive. A number of nonfunctioning islet cell tumors of the pancreas have been described. The lack of function has previously been suggested to indicate the lack of secretion of an endocrine product. This report documents that islet cell tumors may function by secreting pancreatic polypeptide but not cause symptoms.

Adenoma, Islet Cell↗
PubMedDate not supplied

Absence of tubular proteinuria following environmental exposure to chromium.

Certain chromium compounds are known to be nephrotoxic, but renal damage from long-term environmental or occupational exposure to chromium has not been documented. To detect possible preclinical renal damage, we tested the urine of 55 lifelong residents of an area contaminated with chromium landfill. The levels of four proteins were determined in urine samples: (1) human intestinal alkaline phosphatase, (2) tissue nonspecific alkaline phosphatase, (3) N-acetyl-beta-D-glucosaminidase, and (4) microalbumin. No elevated levels of proteins were found, and there were no significant correlations between urine protein and urine chromium concentrations. We concluded that long-term environmental exposure to chromium dust did not lead to tubular proteinuria.

Adult↗
PubMedDate not supplied

Welcome address.

Honorable Prime Minister, Begum Khaleda Zia, honorable Minister for Health and Family Welfare, Mr. Chowdhury Kamal Ibne Yusuf, honorable Secretary of Health and Family Welfare, Mr. Syed Shamim Ashan, Director of ICDDR, B, Dr. Demissie Habte, excellencies, heads of international agencies, it is my pleasure to welcome you all to this important ceremony in celebration of 25 years of oral rehydration solution or ORS. ORS is a remarkably cost-effective, low-technology remedy that can be prepared and used in the home to treat what used to be the world's leading killer of children: diarrheal disease. Through the use of ORS, diarrheal disease had now been demoted to second place among the causes of death among the children of the world. ORS saves a million lives and billions of dollars a year. It is appropriate that we should celebrate this remarkable scientific breakthrough. This function was jointly organized by the Ministry of Health and Family Welfare and ICDDR, B. The fact that we have organized this together illustrates the close working relationship between the Government of Bangladesh and ICDDR, B. ICDDR, B is a remarkable and unique institution. It is the only truly international health and population research institution located in a developing country. This ceremony with the distinguished international audience bears testimony to the global importance, value and success of ICDDR, B's work. On behalf of the Ministry of Health and Family Welfare and the International Center for Diarrheal Disease Research, Bangladesh, welcome.

Asia↗