Search PubMed⌕ Search

Biomedical subjects

S Hamann

Publications and source records attributed to S Hamann.

24 records · Page 2Linked to original sources
PubMed1988

Leukemic dermal infiltrates as a complication of central venous catheter placement.

A leukemic dermal infiltrate at the site of a central venous catheter placement was the first manifestation of relapse in a 58-year-old woman in clinical remission of acute myelomonocytic leukemia. The patient developed a large hematoma around the site of an unsuccessful attempt to place a central venous (CV) catheter. Although the hematoma resolved completely by the time that complete remission was achieved, an indurated, erythematous mass subsequently developed, which when biopsied revealed leukemic cells in the dermis. The patient had a relapse in her peripheral blood shortly thereafter. The authors reviewed recent literature and their own experience with CV catheters and report on localized dermal relapse as a previously unpublished risk of CV catheter placement. They also speculate on the role of the dermis as a sanctuary for leukemic cells and a potential source for relapsing disease.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1979

Effects of lithium on vigilance, psychomotoric performance and mood.

It can be expected that investigations on the effect of lithium on the "normal" human mind may elucidate the influence of lithium on experience and behaviour during the "free interval" of manic-depressive patients. In a placebo-controlled double-blind trial 24 normal healthy volunteers were given lithium sulphate (24--36 mval/die) or placebo over a period of two weeks. The subjects were tested after one and two weeks drug intake using the following tests: quantitative pharmaco-EEG, psychological performance, and mood scales. In comparison to placebo lithium shows decreased flicker fusion threshold, and mood change towards depression (Bf-S). In the resting EEG a decrease of relative slow alpha (7.5--9.0 cps)--and an increase of relative fast beta (20.0--30.0, and 30.0--48.0 cps)--power was observed. The results suggest that lithium leads to decreased vigilance and reduced spontaneous activity.

Adult↗
PubMed1978

[Lithium: EEG, performance and mood under subchronic therapy (author's transl)].

In a controlled double-blind trial 2X12 healthy male volunteers were tested during treatment with lithium sulphate (24--36 mval/d) or placebo. Volunteers were tested after one and two weeks' drug intake using the following tests: Quantitative pharmaco EEG, psychological performance and mood scales. In comparison to pacebo, lithium shows increased mistake duration of the pursuit rotor (MLS), decreased flicker fusion threshold and an impairment of mood. The EEG effects (decrease 7--9 cps, increase 20--50 cps) require further clarification.

Adult↗