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Biomedical subjects

S H Heywang

Publications and source records attributed to S H Heywang.

23 records · Page 2Linked to original sources

MR imaging of the breast using gadolinium-DTPA.

In a preliminary study 20 patients underwent breast examinations by magnetic resonance (MR) imaging without and with Gd-DTPA as contrast medium. All carcinomas enhanced, whereas dysplastic tissue enhanced slightly or not at all. Significant additional diagnostic information was available on the Gd-DTPA examinations in at least four of 20 cases compared with MR without contrast medium and X-ray mammography. Our preliminary results indicate that MR imaging of breast using Gd-DTPA may be helpful for the evaluation of dense breasts and the differentiation of dysplasia and scar tissue from carcinoma.

Biopsy↗

MR imaging of the breast: comparison with mammography and ultrasound.

Fifty-seven biopsy proven breast masses have been examined at our institution by magnetic resonance (MR), mammography, and ultrasound. The three techniques have been evaluated concerning their capability to visualize the lesion and the diagnostic information obtained. Magnetic resonance proved comparable to mammography and superior to sonography in the fatty to medium dysplastic breasts but inferior to the combined examination by mammography and sonography in the dense breasts. In some selected cases, however, special advantages of MR have been found.

Adenocarcinoma, Scirrhous↗

Comparison of CT with MR imaging of endobronchial tumors.

Twenty-nine patients suspected of having an endobronchial mass were examined by magnetic resonance (MR) and CT. Seventy-nine pathological and 319 normal bronchi were confirmed by bronchoscopy and/or operation in these patients. The studies were evaluated by two observers (A and B): By MR, only 72% (A) or 71% (B) of the pathological and 45% (A) or 43% (B) of the normal bronchi, respectively, were visualized. Computed tomography identified all pathological and 97% of the normal bronchi (A and B). Therefore, comparison between MR and CT was based only on those bronchi that were adequately visualized on MR as well as CT. For these bronchi the sensitivity of MR was 88% (A) or 77% (B) and of CT 96% (A) and 93% (B). Specificity was 92% (A) and 94% (B) for MR and 97% (A and B) for CT. At the present stage of development CT proved to be superior to MR in demonstrating endobronchial lesions.

Adenocarcinoma↗

Gd-DTPA enhanced MR imaging of the breast in patients with postoperative scarring and silicon implants.

Sixty patients with postoperative scarring with (30) or without (30) silicon implants have been examined by magnetic resonance (MR) with Gd-diethylenetriamine pentaacetic acid. The 60 patients consisted of 28 patients with obvious normal or abnormal findings and of 32 diagnostically difficult patients, who were referred to MR because of uncertain mammographic and/or clinical findings. Scarring older than 6 months postoperatively did not enhance noticeably, whereas scarring younger than 6 months postoperatively enhanced variably (nonsignificant, borderline, or significant). Since all carcinomas larger than the slice thickness enhance significantly (as also confirmed by other studies) contrast enhanced MR allowed an excellent discrimination between scarring older than 6 months and malignancy. Good visualization of the tissue around silicon implants proved to be another advantage of MR. When its use in the diagnostically difficult cases was analyzed, MR proved quite helpful in 23 of 32 cases by excluding or demonstrating malignancy.

Biopsy↗