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Biomedical subjects

S Gupta

Publications and source records attributed to S Gupta.

At least 1,603 records · Page 89Linked to original sources

Spontaneous colocutaneous fistula in amoebic colitis.

Formation of spontaneous colocutaneous fistula in amoebic colitis is an unusual and rare complication. This case illustrates amoebiasis of the sigmoid colon with pericolic abscess which ruptured externally to develop into a spontaneous colocutaneous fistula. Early diagnosis and proper treatment could have prevented these complications.

Adult↗

A study of clinico-histologic correlation in lesions of borderline leprosy with multiple skin biopsies from different sites.

20 active untreated cases of borderline leprosy were subdivided on clinical, bacteriological and immunological grounds. None had reactional episodes. Multiple skin biopsies from each one of them showed varied histopathology from different lesions. 84 out of 93 biopsies (90.3%) were found not to be in agreement with the clinical diagnosis. Even the multiple biopsies obtained from single large lesion revealed varied histopathological picture. The reason for the histopathological disparity has been postulated.

Adolescent↗

Pattern of leprosy in a city hospital.

A total of 1327 leprosy patients attending one of the leading Delhi hospitals from 1977 to 1982 were reviewed. Leprosy, as such, is not a prominent disease in Delhi, but an influx of patients from the adjoining endemic states of Uttar Pradesh and Bihar has created a challenge because of increased construction activities for the Asiad '82. A relatively large number of patients were recorded during 1980. Most of the patients were unskilled workers. The usual preponderance of males over females was fairly explicit. Patients of low socioeconomic status were seen more frequently than those of higher socioeconomic status. The disease was found in the age group of 20-30 years and, in most cases, the age at onset was between 20-29 years. Infectious cases belonging to the borderline-to-lepromatous (BB-BL-LL) groups were reported more frequently than tuberculoid (TT-BT) cases. A suggestion is made to incorporate neuritic and indeterminate cases in the five-group classification in order to cover the total spectrum of the disease.

Adult↗

Leiomyosarcoma of the mediastinum.

Leiomyosarcomas of the mediastinum are rare tumours, with only four cases reported in the literature. In the absence of any specific clinical pointer for diagnosis, proof comes through histopathologic study. One case of leiomyosarcoma of the superior mediastinum is reported here because of its rarity and an interesting histopathology.

Humans↗

Functional beta cell regeneration in the islets of pancreas in alloxan induced diabetic rats by (-)-epicatechin.

(-)-Epicatechin (1), a naturally occurring flavonoid compound was found to have reversed the diabetogenic action of alloxan in albino rats (2). (-)-Epicatechin administration in doses of 30 mg/kg (i.p.) twice daily for 4-5 days in alloxan induced (150 mg/kg, i.p.) diabetic albino rats (either sex), has brought down the high blood sugar levels to normal values. Concurrent histological studies of the pancreas of these animals showed regeneration of the beta-cell population of the islets which were earlier necrosed by alloxan. Immunoreactive insulin (IRI) studies showed that the regenerated beta-cells of the islets of pancreas are functional in nature.

Animals↗