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Biomedical subjects

S Guerard

Publications and source records attributed to S Guerard.

6 recordsLinked to original sources

[Exertional hypertension and sport].

Defining the normal range of blood pressure during exertion is not easy. Each type of exercise induces increased blood pressure that responds to a particular curve, and adaptation modes differ according to age, gender, physical condition, basal blood pressure, etc. The best studied is blood pressure measured on the arm using a cycloergometre. Classical publications established blood pressure curves according to heart rate during exercise. It appears that the best scale of reference for power developed occurs in individuals who can provide a very high degree of effort and in particular, athletes who are in very good training. According to some authors, hypertension on exertion would entail a poor prognosis, even in the absence of resting hypertension. Nevertheless, there is presently no well established therapeutic recommendation concerning exertion hypertension. This approach could depend on resting blood pressure and on the existence of other risk factors. For an athlete, pursuing physical activity is most often encouraged, sometimes after treatment or adjustment of its level.

Blood Pressure↗

[Retroclival hematoma in a patient taking oral anticoagulants].

Retroclival hematoma associated with anticoagulation. We report a case of retroclival hematoma associated with anticoagulant therapy in a 78-year-old-woman, who presented with an isolated left external ophthalmoplegia. The role of the anticoagulant therapy is discussed. There was a spontaneous neurological resolution.

Aged↗

[A new case of pericardial thymic cyst].

The thymic cysts are benign tumours of the thymo-pharyngeal canal, usually located in the cervico-mediastinal region. The authors report the case of a large thymic cyst with an ectopic right paracardiac location compressing the right heart chambers. It was a chance finding on chest X-ray of an asymptomatic 21 year old man. Though suggestive of a pericardial cyst in view of its position, curative surgical ablation allowed confirmation of the diagnosis at anatomo-pathological examination.

Adult↗

[Chronic occlusion of the left coronary artery].

Chronic occlusion of the left main coronary artery is rare with less than 100 reported cases. the treatment is essentially surgical but medical management has been proposed. This case report illustrates the prognostic benefit of surgical management in view of the risk of secondary occlusion of the proximal right coronary artery.

Chronic Disease↗

Short report: isolation and partial characterization of a Puumala virus from a human case of nephropathia epidemica in France.

Puumala (PUU) virus (Bunyaviridae: Hantavirus), the etiologic agent of nephropathia epidemica (NE), the mid form of hemorrhagic fever with renal syndrome, is enzootic in Europe and has been known to occur in France since 1983. We report the first isolation of PUU virus in France and western Europe from a case of NE acquired in France. The virus was isolated from a serum collected in the acute phase of the clinical course by successive blind passages in Vero E6 cells. Serologic typing using monoclonal antibodies confirmed the identity of the virus as PUU. The sequence of an 832-nucleotide fragment of the virus medium RNA segment obtained by the polymerase chain reaction (PCR) also classified it as a PUU virus. The sequence of this isolate from a human case in France is closely related to the sequence of a PUU virus obtained by the PCR from a German patient.

Adult↗