Search PubMed⌕ Search

Biomedical subjects

S Greenstein

Publications and source records attributed to S Greenstein.

At least 37 records · Page 2Linked to original sources

Small-bowel diverticulitis: CT findings.

Three patients with subsequently proven small-bowel diverticulitis were studied with preoperative CT. In all three cases, an inflammatory mass was present, two involving the terminal ileum and cecum and one involving the jejunum. While the findings in the two cases of ileal diverticulitis simulated appendicitis, in the case of jejunal diverticulitis the diagnosis was suggested on the basis of CT findings. Small-bowel diverticulitis should be included in the differential diagnosis if an inflammatory mass involving the small bowel is demonstrated on CT.

Aged↗

Phthalic anhydride asthma.

A patient with occupational asthma caused by phthalic anhydride is described. Inhalation challenges under laboratory control produced immediate and delayed asthmatic responses. Repeat exposure to phthalic anhydride after treatment with cromolyn sodium showed inhibition of the late but not early bronchoconstrictive, asthmatic response.

Adult↗

Sulfonylurea-induced factitious hypoglycemia in a nondiabetic nurse.

A case of sulfonylureainduced factitious hypoglycemia occurring in a nondiabetic medical nurse is reported. The patient presented with symptoms of hypoglycemia, consistently low fasting plasma glucose values and a reversal of symptoms with glucose administration. An intravenous tolbutamide provocative test on two occasions showed little increase in plasma glucose values. The case is presented to illustrate that sulfonylureainduced hypoglycemia should be considered in the differential diagnosis of fasting adult hypoglycemia, especially in paramedical personnel, and particularly in those with a poor response to the intravenous tolbutamide test.

Adult↗

Relationship of rats' spatial preferences to effects of d-amphetamine on timing behavior.

Rats were trained to bar-press on a differential reinforcement of low rate 16 sec (DRL 16) schedule for water reinforcement. On alternate days, rats were tested in the presence or absence of a light which signaled the availability of reinforcement. Rats were allowed to bar-press on either of two levers (left and right). All rats show consistent side preferences. Doses (0.5-2.0 mg/kg) of damphetamine differentially affected performance under signaled and nonsignaled conditions. Performance during the nonsignaled condition was much more sensitive to a drug-induced rate increment and timing impairment than performance during the signaled condition. With increasing drug dosage, under both conditions, side preferences reliably increased, decreased or remained unchanged depending upon the particular pattern of paw usage and the relationship between paw and side preferences. For the nonsignaled condition but not for the signaled condition, baseline rates were related to the strength of side preferences; lower rates and better timing performance wwere significantly correlated with greater preferences. Observations of bar-pressing behavior suggested that stereotyped motor patterns associated with side preferences might be related to mechanisms involved in timing behavior and perhaps, in behavior controlled by internal stimuli generally.

Animals↗

Possible modulating influence of frontal cortex on nigro-striatal function.

1. After administration of (+)-amphetamine, rats with unilateral ablations of the frontal cortex rotated either ipsilaterally or contralaterally as a function of time after surgery.2. At early postoperative intervals (1-7 days), rotation was towards the side of the lesion.3. At later times (15-30 days), rotation was towards the intact side.4. Repeated testing with amphetamine appeared to slow the time-course of changes in rotational behaviour.5. These results suggest that a dopaminergic nigro-striatal system is modulated by the frontal cortex and that unilateral removal of the latter produces a denervation supersensitivity of the former.

Animals↗