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Biomedical subjects

S Geyer

Publications and source records attributed to S Geyer.

69 records · Page 4Linked to original sources

Childhood head injuries in Israel: epidemiology and outcome.

Results are reported of a regional survey of hospitalized head injuries in Israeli children aged 0-7 years during the period 1970-1976. There were 370 such cases surveyed. Incidence of head injury requiring hospitalization was 1.71/1000 per year. Follow-up examination 4-10 years after injury was achieved in 50 per cent of the cases. Late seizures and focal neurological deficit were rare, while school failure and various neuropsychiatric symptoms were common. Prevalence of seizures and new nervous habits was significantly related to severity of injury, while the prevalence of fears, nightmares, dizziness and school failure was not.

Achievement↗

[Psychosocial competence of general practitioners in managing psychiatric patients: initial results of a questionnaire study].

OBJECTIVE: Given the frequency of patients with psychosocial problems and mental disorders in primary care our study focuses on the relationship between the psychosocial qualifications of general practitioners and their management of these patients. METHOD: A questionnaire was sent to all general practitioners in Hessen asking for sociodemographic and profession-related data as well as their psychosocial competence and their procedure during a regular day in practice. Based on 396 questionnaires we compared five groups of general practitioners with different psychosocial qualifications, proportionate incidence of diagnoses, medical procedures and referrals to specialists and hospitals. RESULTS: The average age of the participants of our study is 45 years, they have been working for 14 years. 163 general practitioners without and 59 with a special interest in psychosocial qualification and 174 psychosocially qualified physicians participated in the study. Of a total of 65 patients seen during the reference day 18 were diagnosed as suffering from mental disorders. Their number increased with greater psychosocial competence of the physicians. Psychosomatic and reactive disorders are the most frequent mental disorders to be seen in primary care with nearly 60%. Verbal therapy is often applied, procedures of the so-called psychosomatic basic care and prescription of psychotropic drugs play only a minor role. Nearly every fourth patient is referred to other specialists, referrals for inpatient treatment occur with 1.3% only. DISCUSSION: Because of the low response rate our study is not representative. Nevertheless the results permit some conclusions concerning the relationship between psychosocial qualification of general practitioners and their management of patients with mental disorders.

Clinical Competence↗

A four-dimensional probabilistic atlas of the human brain.

The authors describe the development of a four-dimensional atlas and reference system that includes both macroscopic and microscopic information on structure and function of the human brain in persons between the ages of 18 and 90 years. Given the presumed large but previously unquantified degree of structural and functional variance among normal persons in the human population, the basis for this atlas and reference system is probabilistic. Through the efforts of the International Consortium for Brain Mapping (ICBM), 7,000 subjects will be included in the initial phase of database and atlas development. For each subject, detailed demographic, clinical, behavioral, and imaging information is being collected. In addition, 5,800 subjects will contribute DNA for the purpose of determining genotype- phenotype-behavioral correlations. The process of developing the strategies, algorithms, data collection methods, validation approaches, database structures, and distribution of results is described in this report. Examples of applications of the approach are described for the normal brain in both adults and children as well as in patients with schizophrenia. This project should provide new insights into the relationship between microscopic and macroscopic structure and function in the human brain and should have important implications in basic neuroscience, clinical diagnostics, and cerebral disorders.

Adolescent↗

Efficacy of splenectomy for patients with mantle cell non-Hodgkin's lymphoma.

The purpose of this study was to define the role of splenectomy in patients (pts) with mantle cell lymphoma (MCL) with regard to improving cytopenias and symptoms of splenomegaly. 26 pts with MCL underwent splenectomy between January 1987 and October 1999 and were followed prospectively for hematologic response and operative morbidity and mortality. A positive response was defined at 1 month of follow-up as: a hemoglobin of > or = 1.0 g/dl in a pt with a preoperative value < 11.0 g/dl; or a platelet count of > or = 100 x 10(9)/L in a pt with a preoperative value < 100 x 10(9)/L. A positive hematologic response was achieved in 69.2% of pts with preoperative anemia, 90% with thrombocytopenia, and 50% with both anemia and thrombocytopenia. The peri- and post-operative morbidity were 3.8 and 19.2%, respectively, the operative mortality was 0%. The median duration of hospitalization was six days. Four (15.4%) pts have not required chemotherapy after splenectomy. Three of these four were previously untreated and they have maintained stable disease for eight years after splenectomy without chemotherapy. Eight additional pts did not require chemotherapy for > 13 months after splenectomy. These results suggest that splenectomy may provide durable remission in selected pts with refractory cytopenias or symptoms related to splenomegaly in pts with MCL. There is a subset of pts that have prolonged disease stabilization without the requirement for immediate chemotherapy after splenectomy.

Adult↗

[Accident-related hospital admission of children and adolescents in relation to their social status--findings with data from North Rhine-Westphalia federal health insurance].

This paper review examines whether there are health inequalities in terms of hospital admissions due to accidents in children and adolescents in Germany, and whether the social gradient varies according to age and gender. Analyses are based on information from a statutory health insurance North-Rhine Westphalia. The social structure of these insured persons does not correspond to the German population. Lower social positions are predominant while persons holding higher positions are under-represented and professionals are virtually absent. Data were compiled from hospitals, routinely transmitted from employers and from data collections by the insurance for accounting purposes. 47,427 records of children and adolescents below the age of 17 were included; altogether 4246 accidents were recorded. Hospital admissions following accidents showed a clear social gradient. The odds-ratio (OR) of children with an unskilled/semi-skilled background as compared to the highest occupational position considered was OR = 1.4. Social gradients differed by gender and age. The respective odds-ratio for the group below 6 years was OR = 0.9, for ages 6 to 10 OR = 2.2, and OR = 1.4 for ages 11 to 16. The interpretation of age-specific odds-ratios is impaired by low numbers of events in the highest status group. Girls had a lower rate than boys. With regard to accidents, children and adolescents who could not be classified according to their socioeconomic status were similar to the two lower status groups. These findings are comparable to results of the few international studies in this research area. They suggest the necessity of preventive efforts to reduce social inequalities in the lower status groups.

Accidents↗