Biomedical subjects

S Garson

Publications and source records attributed to S Garson.

6 recordsLinked to original sources

PubMed2006

[Bilateral breast reconstruction with the autologous latissimus dorsi flap (a retrospective study of 31 consecutive cases)].

PURPOSE OF THE STUDY: The purpose of this study was to analyse the advantages, disadvantages and results of bilateral breast reconstruction by autologous latissimus dorsi flap. MATERIAL AND METHOD: Thirty-one two-stage consecutive bilateral breast reconstructions were performed by the same operator between 1993 and 2001. All the reconstructions, in immediate or delayed manner, were indicated after radical or skin sparing mastectomy for breast cancer. We used the autologous latissimus dorsi flap for all cases. The reconstruction of the second breast was always delayed of a few months to avoid back's complications. We reviewed the charts of these patients retrospectively. Preoperative data, postoperative complications, dorsal seroma occurrence, morphological results and patient's satisfaction were evaluated. Median follow-up was 22 months. RESULTS: The results confirm the procedure's reliability. Comparative rates of postoperative complications are not significantly different between first and contralateral breast reconstruction. Functional after-effects of bilateral latissimus dorsi harvesting are moderate. The aesthetics results have been judged as very good in 84% of cases and good in 16%. The satisfaction rate of the patients is high: 90,3% are pleased, 6,5% are satisfied and 3,2% are moderately satisfied. CONCLUSION: The autologous latissimus dorsi flap allows a two-stage bilateral breast reconstruction. This procedure is not indicated for simultaneous bilateral breast reconstruction; it is the main drawback of this technique. So we believe that this procedure is an excellent alternative in all the indications of sequential bilateral breast reconstructions.

Adult↗

PubMed2005

[Scientific bases of fat transfer. Critical review of the literature].

Fat grafting is an old technique. Since its first description in 1893, fat was used in a lot of indications. After more then a century of evolution, there is still no commonly accepted standard method of fat transfer by all the authors. On the contrary, many different techniques have been described in the literature with the only aim of reducing resorption of the transferred fat. Today the main inconvenient of fat grafting remains the partial resorption the transferred tissue. After a review of the literature of the various technique of fat transfer presented according to their chronology in the operative procedure, we have observed that the techniques developed by certain authors are the opposite of the techniques developed by others. This shows the lack of rigorous work concerning the fat transfer. Whether they are experimental or clinical, in most of these studies, we can find at least one skew which could have influence the results and the conclusion of these studies. A critical revue of the literature offers the opportunity to reconsider the actual bases of fat transfer. The use of an objective way of quantifying the volumes in clinical practice could permit the comparison of different studies in the future.

Adipose Tissue↗

PubMed2005

[3D evaluation and mammary augmentation surgery].

The medical application of the interferometry is valid now. The breast surgery works on the shape and the volume of the tissue. The Inspeck technology is now available and works well in our medical practice. The measurement tools for the lengths, euclidian or projected on surface are working well with the same precision of a manual measurement. The estimation of the volume needs to follow exactly the same procedure to get some good results. The virtual breast modification doesn't work anymore with a scientific precision and does not allowed yet an office use. A development of the software is necessary to use all these data enclosed in the 3D models.

Adult↗

PubMed2005

[3 D evaluation and breast plastic surgery: preliminary study].

Due to the development of the invasive technique of digital exam, the three-dimensional results are more and more precise, spectacular and helpful. The 3D surfacic model is for a medical approach and non invasive. Early in 2003, we have started a patient evaluation before and after surgery. The most common surgical techniques from the breast reconstruction to the breast augmentation and the lipomodeling have been analyzed. This preliminary study has shown objectively some surgical rules and volumetric results. Those results are the elements of the future development of the 3D surfacic model in plastic surgery.

Breast↗

PubMed2002

[Burned lips].

The burns of the mouth and the lips, even electric are rare. The respect of the news prevention's norm modify the incidence of these burns. The progress of the management these last 40 years, contributed to the improvement of the functional and aesthetic prognosis. The early surgical intervention has been modified for a conservative approach. Three points are discussed by authors: anatomoclinical particularities in case of different burning; early management; sequelae treatment.

Burns↗

PubMed1981

Trypanosoma rhodesiense: chemical and immunological characterization of variant-specific surface coat glycoproteins.

Soluble surface coat glycoproteins were purified by concanavalin A affinity chromatography from variant populations of Trypanosoma rhodesiense (Wellcome strain). Each variant yielded a glycoprotein consisting of a single polypeptide chain. The apparent molecular weights of the different glycoproteins ranged from 58 000 to 67 000. Charge heterogeneity analyses resolved from 1 to 3 closely spaced components with isoelectric points that were considerably different from variant to variant. Amino acid analyses revealed notable variations in amino acid compositions. Immunization of mice with purified glycoprotein protected them from homologous variant trypanosome infection. Hyperimmune sera raised to purified glycoproteins were obtained from rabbits and produced single precipitin lines in immunoelectrophoretic or immunodiffusion tests with homologous glycoproteins. No interaction could be detected in heterologous antiserum-glycoprotein combinations. Only variant homologous trypanosomes were agglutinated by antisera. Surface coat glycoproteins prepared from clone populations of variants were chemically and immunologically indistinguishable from the glycoproteins of original uncloned variants. The observed immunogenic specificity and chemical uniqueness of the glycoprotein preparations identify them as variant-specific surface coat antigens responsible for antigenic variability in T. rhodesiense.

Animals↗