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Biomedical subjects

S Gandolfo

Publications and source records attributed to S Gandolfo.

At least 109 records · Page 6Linked to original sources

[Verrucous carcinoma of the oral cavity; critical review of biopsied cases and a retrospective study of the clinical course in 14 patients].

With the view of studying the prognosis and therapy of "verrucous carcinoma", the authors have examined the follow-up of 14 patients, suffering from this neoplastic disease. They have pointed out a certain unhomogeneity in the results and this has most probably to be ascribed to an irrational therapeutical treatment and in particular to the possible negative influence of radiotherapy. The authors wish therefore to reaffirm the need to shortly come, also in this field to a rationalization of the therapeutic protocol.

Adult↗

[Our clinical experience with the cryosurgery of oral lesions of odontostomatologic interest].

Three years' experience in the field of therapeutic cryosurgery is described. During this period, 125 patients were treated and excellent results were achieved. Carcinomas of the oral cavity, leukoplakias, and angiomas formed the bulk of the series. It is submitted that this form of management can be looked upon as the treatment of choice in these forms.

Cryosurgery↗

[Cryotherapy, combined drug therapy and radiotherapy in the treatment of oral cavity cancer: 3 years' experience].

The medium-term (three years) result of a multidisciplinary association treatment of carcinoma of the oral cavity has been reviewed. Treatment was Cryosurgery-polychemotherapy-ratiotherapy and the technique has been described along with the times of association in an introduction that has already been published in this review (see bibliography). Thirty patients were treated with the association because they refused or could not be submitted to surgery at the intital therapeutic action. All these patients present fairly extensive lesions and a three-year follow-up. Results were positive: 56.6% of patients showed disappearance of any objective or subjective sign of cancer and, in all cases, appreciable remission in terms of both extent and duration. The easiness of the technique is confirmed as well as the excellent conversation of the anatomical structures involved. However, a critical review of cases presenting partial failure suggest a classifications of oral carcinomatous lesions (for therapeutic purposes only) on the basis of which the condition can be treated with cryo-polychemo-radiotherapy alone or with a variation of this which provides for the addition of local exersis.

Adult↗