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Biomedical subjects

S G Srikanth

Publications and source records attributed to S G Srikanth.

21 records · Page 2Linked to original sources

Symptomatic vertebral haemangioma: endovascular treatment of 12 patients.

Vertebral haemangioma is a well known albeit infrequent cause for thoracic cord compression. While surgery is the treatment of choice in patients with neural compression syndromes, embolization of the feeding arterial pedicles is less frequently practiced. Twelve patients with vertebral haemangiomas and neural compression underwent particulate embolization of the feeder arteries. Eleven patients had a subsequent decompressive laminectomy. At 8 months of follow-up after radiotherapy, eleven patients had improved and in one patient, the clinical deficits were unchanged. Immediate pre-operative particulate embolization is to be considered in patients with a symptomatic spinal haemangioma.

Adolescent↗

Ossification of the posterior longitudinal ligament of the cervical spine in Asian Indians--a multiracial comparison.

Ossification of the Posterior longitudinal ligament (OPLL) has been thought to be a predominantly Japanese disease with few reports among the non-orientals and Caucasians. A prospective clinicoradiological study of 47 symptomatic Caucasoid Indians is reported. Twenty-seven patients presented with myelopathy, twelve with myeloradiculopathy and six with radiculopathy. 'Total' configuration of OPLL was the most frequent (70%). The most frequent location was at C3 and C4 levels. The thickness of OPLL ranged from 2.5 mm to 11.5 mm. Canal stenosis was most severe in patients with 'total' type of OPLL. Ossification of other spinal ligaments were seen in 50% of the patients. Twenty-one patients underwent decompressive laminectomy and twenty of them improved. The difference in the cervical canal diameters and the configuration of OPLL between the Japanese and our population (Caucasoid Indians) may be of therapeutic relevance.

Adult↗

Radiological findings in moyamoya disease.

The clinical, angiographic and computed tomographic features in eight children with Moyamoya disease were evaluated. The CT Scan findings were correlated with the angiographic features and the stage of the vascular disease. Stenosis/occlusion of the supraclinoid internal carotid artery (ICA) and the proximal parts of the anterior (ACA) and middle cerebral arteries (MCA) were commonest angiographic findings. The cervical ICA was narrow in four patients. Infarcts (100%), abnormal enhancement patterns (63%) and cerebral atrophy (88%) were the frequent CT scan findings. Although the CT scan findings did not correlate entirely with the angiographic and clinical findings, they were more frequently abnormal in later stages of the disease. The volume of Moyamoya increased progressively up to stage 3 of the disease only to decrease with further progression. The etiology of Moyamoya disease in Indian children is not clear. However, the clinical and radiological features are similar to that in the Japanese.

Cerebral Angiography↗