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Biomedical subjects

S G Harner

Publications and source records attributed to S G Harner.

71 records · Page 4Linked to original sources

Auditory brainstem responses in ears with hearing loss: case studies.

Auditory brain stem evoked responses (ABRs) were recorded from six selected adult patients with various audiometric configuration, histories, and diagnoses. Although none of the patients were diagnosed medically as having retrocochlear disease, ABR latencies and waveform morphology were considered abnormal in some cases. By contrast, other patients with similar hearing loss configuration yielded normal ABRs. These observations emphasize the potential difficulty encountered in the interpretation of ABRs when hearing loss exists. Further, because ABRs and all other special auditory tests are not diagnostic extreme caution should be exercised prior to any definitive interpretation and subsequent diagnosis.

Adult↗

Intracranial ceruminous gland adenocarcinoma.

Patients with adenocarcinoma of the ceruminous gland arising in the middle ear have a typical syndrome consisting of unilateral hearing loss, otalgia, facial paresis, and a middle-ear mass. Adjacent cranial nerves also may be affected. Some patients may have an ipsilateral cerebellar ataxia if the lesion extends into the cerebellopontine angle and compresses the cerebellar hemisphere. Obstructive hydrocephalus may occur secondary to obstruction of the aqueduct or fourth ventricle. The initial clinical findings may be those of a jugular foramen syndrome. These lesions are usually slow-growing and may be associated with a very prolonged clinical course. Although the tumors are rare, the physician should be aware of their existence if proper care is to be given.

Adenocarcinoma↗

Lymphocytic lymphoma involving the middle ear.

A patient with lymphocytic lymphoma involving the middle ear had otalgia and facial palsy as his initial symptoms, and the definitive diagnosis was made by means of biopsy of the tumor in the middle ear. Review of the literature revealed only one other case with clinical involvement of the middle ear space.

Aged↗

Experience with a polyethylene total ossicular replacement prosthesis.

Surgical reconstruction of ossicular defects in chronic middle ear disease is a difficult problem. We have reviewed our results with the use of the Plastipore total ossicular replacement prosthesis (TORP). Of 29 procedures that were analyzed, nine were considered successful. None of our patients had a stapes superstructure, and 13 had no malleus. Placement of the TORP under the malleus handle and use of extra tissue between the prosthesis and the tympanic membrane provided better hearing results, but extrusion of the prothesis still occurred. Positioning of the prosthesis and contraction of the middle ear space, which causes extrusion of the prosthesis, remain problems in this type of reconstruction.

Adolescent↗

Nasal polypectomy in patients with asthma and sensitivity to aspirin.

Nasal polypectomy is safe in patients with asthma and intolerance to aspirin. Asthma should be controlled before polypectomy. Patency of the nasal airway after the operation and the effect of polypectomy on asthma are independent of severity of the asthma, history of atopy, and administration of steroids. We reviewed retrospectively the courses of 101 patients with the asthma triad who had nasal polypectomies between 1970 and 1974. Before polypectomy, 39 patients were hospitalized to control active asthma: during the postoperative hospitalization, 19 had wheezing, mostly mild. Of the 62 patients with inactive asthma, three had wheezing postoperatively. Asthmatic condition at one year after polypectomy, compared with the condition at one year before, was improved in 30 patients, worse in 14, and unchanged in the rest. Nasal airways remained good for at least one year in 60% of the patients.

Adolescent↗

Foreign bodies in the ear, nose, and throat.

Foreign bodies of the ear should be removed by irrigation, suction, or forceps. General anesthesia may be necessary. Foreign bodies of the nose should be removed with suction or forceps, and sometimes intubation may be necessary. Most foreign bodies in the throat can be removed by use of a mirror and a long hemostat.

Drainage↗

Peritonsillar, peripharyngeal, and deep neck abscesses.

Abscesses of the peritonsillar and peripharyngeal regions typically present as a sore throat and as difficulty in swallowing. One of the most ?striking clinical features is difficulty in controlling saliva. Deep neck abscesses usually are secondary to disease in the pharynx, tonsils, or teeth. Initially, attention should be devoted to finding the primary source of infection. Treatment of these abscesses is incision and drainage.

Abscess↗

Brainstem responses to tone pip and click stimuli.

Brainstem auditory-evoked responses to tone pips at 1000, 2000, and 4000 Hz and clicks were evaluated for 17 normal-hearing adults. Wave V consistently emerged as the best indicator of auditory sensitivity, whereas waves II, III, and IV generally were not identifiable at lower intensities. An inverse relationship existed between wave V latency and intensity and between wave V latency and stimulus frequency. Large ranges were noted for the levels at which the various components became identifiable. Even though some frequency specificity may have occurred, the range of wave V latencies for 1000- and 4000-Hz tone pips demonstrated considerable overlap.

Adult↗

Auditory brain stem response results from 255 patients with suspected retrocochlear involvement.

Auditory brain stem response (ABR) evaluations were conducted on 255 patients with suspected retrocochlear involvement. Twenty-six patients (10%) had surgically confirmed tumors, and ABRs were abnormal in 25 (96%) of these cases. The remaining 229 patients had nontumor medical diagnoses, but 25% of these were found to have abnormalities in ABR recordings. The most common ABR abnormality in the nontumor patients was large wave V interaural latency difference, followed by no response or poor waveform resolution and delayed absolute wave V latency. Peripheral hearing loss, including decreased sensitivity at 2000 and 4000 Hz, appears to have influenced waveform morphology and component latency.

Brain Stem↗

Histologic study of the vestibulocochlear nerve.

The vestibulocochlear nerve was studied histologically in cross section from the brain stem to the lateral fundus of the internal within the posterior cranial fossa. The cochlear fibers were denser and darker than the vestibular. This difference created double staining of the eighth cranial nerve in the posterior cranial fossa. At the porus acusticus, the nerve fibers became myelinated. Myelin appeared on vestibular fibers more medially than on cochlear fibers. A discrete point of vestibular-cochlear separation was consistently identified in the lateral portion of the internal auditory canal near Scarpa's ganglion. These results suggest that the most reliable point for discrimination of cochlear from vestibular nerves occurs inside the internal auditory canal.

Adult↗

Paget's disease and hearing loss.

Hearing loss, tinnitus, and vertigo have long been associated with Paget's disease of the bone. We reviewed the records of 463 patients with Paget's disease who were seen in the otolaryngology department. Hearing loss was common. It was our observation that mixed hearing losses were part of the disease process. Sensorineural hearing loss was the most frequent loss, but it usually was not part of the disease process. Tinnitus, vertigo, or both were seen in about 20% of these patients.

Adult↗

Benign chondroblastoma of the temporal bone.

Benign chondroblastoma is a rare tumor in the temporal bone. It occurs preponderantly in middle-aged men as a mass in the postero-superior region of the ear canal and is accompanied by hearing loss. On pathologic examination, giant cells and focal regions of chondroid differentiation are noted. After the extent of the tumor has been determined, the treatment is surgical removal. Preoperative irradiation may be helpful. Long-term follow-up is essential.

Adult↗

Effects of large-bore middle ear ventilation tubes.

Patients with chronic otitis media that did not respond to conventional treatment were studied for the types and incidence of complications from the use of large-bore tubes inserted into their ears. The most common complication was otorrhea (41%, 50 of 123 ears). Permanent perforation occurred in 25% (17/68 ears). Use of large-bore tubes proved effective and continues to be indicated in certain conditions of chronic otitis media that are refractory to other forms of treatment.

Adolescent↗

The anatomy of congenital choanal atresia.

Congenital choanal atresia is rare. Previous literature has dealt with the diagnosis and management of these patients, but there are no reports that accurately describe the nature of the deformity. This is a presentation of two patients with tomographic demonstration of the abnormality which confirms the surgical descriptions of previous authors. These abnormalities are (1) narrowing of the entire nasal chamber, (2) primary bony obstruction with an area of membranous obstruction, and (3) gross deformity of the vomer.

Child↗

Hearing in adult-onset diabetes mellitus.

Hearing acuity and otologic symptoms were examined in 200 patients with adult-onset diabetes mellitus. Data were analyzed according to sex and age and were compared with values of other documented studies; values were within normal limits except in two instances. Speech testing revealed that median speech reception thresholds and median discrimination scores were at the lower limits of normal. Hearing loss and otologic problems did not occur with any increased frequency in patients with adult-onset diabetes mellitus.

Adult↗