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Biomedical subjects

S Furuya

Publications and source records attributed to S Furuya.

At least 181 records · Page 10Linked to original sources
PubMed1976

[Clinical experience with gentamicin in complicated urinary tract infections (author's transl)].

Gentamicin (GM) was intramuscularly administrated to 25 patients with complicated urinary tract infections in doses of 20-120 mg a day for 4-16 days. The results obtained are as follows: 1. The clinical results of GM were excellent in 4, good in 3, fair in 1, poor in 3 and indeterminate in 14 patients out of 25 patients. The effective percentage was 63.6% (7/11). 2. The clinical results of GM against 20 isolates were excellent in 4, good in 3, fair in 1, poor in 3 and indeterminate in 9 isolates. The effective percentage was 63.6% (7/11). 3. In laboratory examinations, BUN elevation was noted in 1 patient, GOT elevation in 2 patients and GPT elevation in 1 patient during GM therapy. No other abnormal findings were observed in this clinical study.

Adolescent↗
PubMed1975

Absorption of L-histidine and glucose from the jejunum segment of the pig and its diurnal fluctuation.

1. Flow rate of digesta and its component in the upper jejunum, and the absorption of L-histidine and glucose from the jejunum segment were measured in pigs fitted with three simple cannulas. The pigs were fed once faily at 08.30 hours. 2. Maximum flow of digesta was obtained in the period 10.00-10.30 hours; the flow rate decreased with time after feeding, reaching a minimum in the period 22.00-22.30 hours. 3. The absorption rate for L-histidine and glucose increased in a hyperbolic manner with increasing concentrations of infused test material, which ranged from 2.5 to 20 g/1 for each material. 4. L-histidine and glucose were absorbed nearly independently when perfused in combination. The absorption rates for glucose were significantly (P less than 0.01) greater than the corresponding rates for L-histidine at each concentration of infusate. 5. The absorption of both L-histidine and glucose expressed as a percentage of the amounts in the perfusate decreased with increasing flow rate of perfusate, from 400 to 800 ml/h. The increase in flow rate from 400 to 800 ml/h was associated with a 20% increase in L-histidine absorption rate; there was a 30% increased in glucose absorption rate when the flow rate was increased to 600 ml/h, but no further incrase at 800 ml/h. 6. The absorption of both L-histidine and glucose decreased with time after feeding; the absorption rates for L-histidine and glucose measured for the period 10.00-22-30 hours were 126 and 133%, respectively, of those measured for the period 22.00-22.30 hours.

Animals↗
PubMedDate not supplied

Flow velocity of the cortical vein and its effect on functional brain MRI at 1.5T: preliminary results by cine-MR venography.

The purpose of this study is to demonstrate the effect of altering flow velocity of cerebral cortical veins as the source of the signal change observed in functional magnetic resonance imaging (fMRI) of the brain. 10 healthy volunteers were examined after instructions in self-paced hand grasping. Experiments were performed using a 1.5-Tesla whole body MR scanner with a conventional two-dimensional gradient echo sequence (TR/TE/flip angle 400/60/40, first order flow rephased, reduced band width 8 Hz/pixel). Flow velocity measurements were performed for the cortical veins which corresponded to the activated areas depicted on fMRI. Velocity was estimated from the cine-MR venography (cine-MRV) with a tagging technique. Flow phantom studies were performed to delineate the effect of flow velocity differences upon the subtraction images of fMRI. The cine-MRV revealed increased flow velocity of the cortical veins during activation in seven volunteers, with a mean velocity difference of 15 mm/sec. Flow phantom studies suggested that the increased flow velocity may result in changes of the flow signal profile due to oblique flow displacement. Subtraction of the two images with different flow profiles produces flow signal enhancement. Increased flow velocity of the cortical veins during the activation is an important factor which contributes to the signal of fMRI.

Adult↗
PubMedDate not supplied

Actin like filaments in the peritubular cells of human testis chemical extraction and binding with heavy meromyosin.

Two types of the cytoplasmic filaments are found in human peritubular cells; thin filaments (50-80 A) and 100 A filaments. The thin filaments are numerous and tightly packed in cytoplasma of peripheral cell processes, and form bundles. These bundles are arranged in parallel with the long axis of the cells. Dense areas are occasionally seen among the filaments, or underneath the cell membrane to which the thin filaments seem to be anchored. The 100 A filaments are generally located around the perinuclear region or in the middle region of cytoplasma. The thin filaments are not altered after incubation with Hasselbach-Schneider's solution. These filaments, however, disappear in cytoplasma when extracted with 0.6 M KI solution. And also, the thin filaments form chracteristic arrowhead complexes, when incubated with HMM, while these complexes are never found, when incubated with HMM plus ATP. The 100 A filaments do not react to HMM. Thus it is suggested that the thin filaments are actin or actin like and that a contractile system exists in human peritubular cells, which may be involved in transport of nonmotile sperm or permeability of the seminiferous walls.

Adult↗