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Biomedical subjects

S Fukai

Publications and source records attributed to S Fukai.

At least 55 records · Page 3Linked to original sources
PubMed1982

Resection of the trachea infiltrated by thyroid carcinoma.

Twenty-four thyroid carcinoma patients with infiltration of the trachea were treated surgically. The histological diagnosis in these cases included papillary adenocarcinoma in 22 different patients, medullary carcinoma in one patient, and undifferentiated carcinoma in one patient. In 19 of the patients hemoptysis was noted, and dyspnea was present in ten patients. In 14 of the 24 patients the carcinoma was diagnosed by radiographs of the neck, while in seven patients it was demonstrated bronchoscopically. In three patients tracheal infiltration by thyroid carcinoma was diagnosed by biopsy of the tracheal wall at operation. When the tracheal wall was infiltrated by thyroid carcinoma, treatment consisted of circumferential resection of the involved segment of the trachea followed by an end-to-end anastomosis. Of the 24 patients, 17 survived and six died. In the 17 patients who survived, 13 were disease free. Of this number, six survived more than five years after the initial tracheal resection.

Adenocarcinoma, Papillary↗
PubMed1980

Parathyroid carcinoma with tracheal invasion and airway obstruction.

The following report presents an unusual case of a patient with a recurrent parathyroid carcinoma that grossly invaded the lumen of the trachea with a polypoid appearance and brought about severe airway obstruction. The three rings of the upper trachea, including the lower part of the cricoid cartilage, were resected with the tumor, and the airway was reconstructed by end-to-end anastomosis. The present case demonstrates that parathyroid carcinoma can become an intratracheal hazard, as can carcinomas of the thyroid gland, esophagus, lung, or larynx.

Adult↗
PubMed1978

Resection of thyroid carcinoma infiltrating the trachea.

We have treated surgically 11 patients with thyroid carcinoma that had infiltrated into the trachea. Three patients had primary tumours, and eight had recurrent tumours after previous operations. Sleeve resection of trachea was performed where thyroid carcinoma had proliferated; the trachea was reconstructed by end-to-end anastomosis. In two patients 10 rings of the trachea were resected. In three patients the anterior half of the cricoid cartilage was resected along with the cervical trachea. In one patient tracheoplasty was performed using partial extracorporeal circulation because severe tracheal stenosis prevented endotracheal intubation. Two of the 11 patients died from the surgery and one from disseminated metastases. One patient who had undergone tracheal resection for thyroid carcinoma three years and five months previously had a recurrence of the tumour in the trachea adjacent to the anastomosis, and a second tracheal resection was performed. In three patients postoperative laryngeal stenosis occurred. Five patients are alive and well two years and one month to four years and seven months after their operations. The histological pattern of the tumour was papillary adenocarcinoma in all 11 patients.

Adenocarcinoma, Papillary↗
PubMed1978

Sequential evaluation of DNCB reactivity in patients with primary lung cancer. Correlation with prognosis.

Delayed hypersensitivity reactions before therapy in 137 patients with lung cancer and in 50 patients with benign thoracic lesions were evaluated by 2,4-dinitrochlorobenzene (DNCB) contact sensitization using the patch test. Ninety-eight percent (49/50) of control patients and 46 percent (62/137) of patients with lung cancer were sensitized by 250 mug of DNCB. There was an excellent correlation between the initial reactivity to DNCB and resectability. In patients with resectable lung cancer, preoperative DNCB reactivity has no prognostic value. However, an excellent correlation was found between postoperative reactivity and 2 year survival, i.e., conversion from unresponsive to responsive status was observed on sequential testing. In 15 of 74 patients with resectable disease, the conversion was noted postoperatively, and among 12 patients followed for 2 years, only two patients had died. Conversion from a reactive to nonreactive status to DNCB occurred only in the terminal stage of the disease. From these observations, we found that, in order to evaluate the afferent limb of cellular immunity in patients with lung cancer who have once expressed reactivity to DNCB, one must use some new sensitizing agents which show no cross-sensitivity with each other thereafter.

Adult↗
PubMed1977

Malignant change in a solitary hamartoma of the lung. A case report.

A case report of a malignant hamartoma of the lung observed in a 36-year-old housewife was presented. The hamartoma was non-chondromatous (fibromyomatous), located beneath the pleura of the left upper lobe. The malignant lesion corresponded to anaplastic carcinoma of the lung. A review of the literatures on the malignant hamartoma of the lung revealed rare incidences of the tumor, but hamartoma and hamartomatous lesions of the lung should be regarded as one of the histopathological backgrounds where pulmonary carcinoma may arise.

Adult↗
PubMed1977

Resection of cancer of lung and carina.

In 3-cases in which lung cancer had occurred in the right upper lobe bronchus and had infiltrated the carina, the right upper lobe (including the lower part of the trachea, the carina, and the right main bronchus) was resected, and a new carina was created by anastomosing the trachea with the left main bronchus and the right intermediate trunk. Surgical techniques and the method for anesthesia were described in these 3 cases. To evaluate the function of the reconstructed trachea and bronchus, we made cinebronchograms at the high speed of 100 or 150 frames per second. This bronchographic movie film helped us to determine the state of the reconstructed trachea and bronchus.

Bronchi↗