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Biomedical subjects

S Ferri

Publications and source records attributed to S Ferri.

At least 127 records · Page 7Linked to original sources
PubMed1984

Cannabinoid level in the leaves as a tool for the early discrimination of Cannabis chemiovariants.

One hundred and seventy-six plants of 22 different lots of Cannabis sativa L., grown at the Botanical Garden of Siena (Italy) were chromatographically analysed in order to define the cannabinoid content in their leaves. The content of the major cannabinoids, delta 9-tetrahydrocannabinol, cannabidiol, cannabinol and cannabichromene, determined weekly in vegetative and floral leaves enabled the determination of the chemical types of the plants, according to Turner's classification. The plants were easily distinguishable in drug, intermediate and fiber types. The cannabinoid characteristic of each type remains predominant, as compared with the other cannabinoids, throughout the whole period of growth, including the floral stage and after harvesting. On this basis, the predominant concentration of a specific cannabinoid can be used reliably for forensic application concerning drug-suspected material in very young plants.

Cannabinoids↗
PubMed1984

Electron microscopic study of teleost (Pimelodus maculatus) pancreatic islet cells.

The endocrine pancreas of the freshwater teleost Pimelodus maculatus was studied by electron microscopy. Based on the granule morphology 2 cell types were described: Secretory granules of type I cells are rounded, nearly completely filling the limiting membranous sac which measures from 120 to 150 nm in diameter; the type II granules are also rounded and measure from 220 to 270 nm in diameter; they consist of an eccentrical electron dense core separated from the limiting membrane by a wide electron lucent halo. These characteristics are correlated with those found in other teleosts.

Animals↗
PubMed1984

Quantitative description of a teleost exocrine pancreas. Ultrastructural morphometric study of nonstimulated acinar cells.

The quantitative analysis of exocrine pancreas was fulfilled in teleost fish ( Pimelodus maculatus). The volume fraction occupied by acinar cells, blood vessels and ducts has been assessed by point-counting volumetry in 0.25 micron araldite sections. Measurements of the diameters of the transections of acinar cells nuclei and nucleolus allowed the assessment of the mean nuclear and nucleolar volume according to the method of Bach (1963). With these data, the cytoplasm nuclei and nucleolus volume was calculated in cubic micrometers. Morphometric ultrastructural data was obtained by applying over the electronmicrophotographs (X 21,000) a test system of 84 segments regularly spaced one from another (Weibel 1966). The results obtained was analysed and compared to the mammalian.

Animals↗
PubMed1983

[Our experience with the effectiveness and tolerance of ibuproxam in rheumatology].

The tolerance and effectiveness of Ibuproxam were investigated in 54 patients with arthrosis, R.A., ankylosing spondylitis, and fibrositis. Statistically significant reduction of pain at the end of the treatment was accompanied by decreased limitation of joint movement and morning stiffness. Simultaneous investigation of clinical and biological tolerance showed that the drug is infrequently responsible for side-effects that are always of negligible importance. Oesophagogastroduodenoscopy in subjects with a prior history and/or signs of active pathology of the upper digestive tract did not reveal exacerbation or recrudescence of lesions, nor the appearance of acute lesions.

Arthritis, Rheumatoid↗
PubMed1983

[Unusual rheumatology cases].

A series of clinical cases very rarely observed in rheumatology is presented. These cases consist of osteoid-osteoma, osteogenesis imperfecta, pachydermo-periostosis, multiple chondromatosis, osteopecilia, Camurati-Engelmann disease. The caracteristics of the patients examined are appropriate and well adapted to the typical clinical studies of these diseases, and are considered current with the contributions concerning rheumatology appeared in the most recent literature.

Adult↗
PubMed1983

Effects of hypothalamic lesions on the content of dynorphin immunoreactivity in pituitary.

Radiofrequency lesion of medial basal hypothalamus (MBH) caused a approximately 50% depletion of immunoreactive dynorphin (ir-dyn) both in the anterior and neurointermediate lobe of the pituitary, whereas radiofrequency lesions of both supraoptic and paraventricular nuclei (SON, PVN) resulted in an approximately 30% reduction in neurointermediate lobe only. MBH cells and/or fibers contribute, therefore, to adenohypophysis pool of ir-dyn. Moreover, since the loss of ir-dyn in neurohypophysis ascertained after MBH lesion is significantly higher than that obtained with SON and PVN destruction, it may be assumed that MBH also participate to ir-dyn pool in neurohypophysis.

Animals↗
PubMed1983

Central and peripheral sites of action for the protective effect of opioids of the rat stomach.

Rats exposed to combined cold and restraint exhibited a reduced intensity of gastric damage when pre-treated intraperitoneally with morphine HCl or with the synthetic enkephalin analog [D-Ala2, MePhe4, Met(0)5ol]enkephalin (FK 33-824). Morphine HCl and FK 33-824 prevented some of the indices of the lesion also when injected intracerebroventricularly; morphine methyliodide, quaternary derivative of morphine with does not cross the blood brain barrier, was fully effective, by intraperitoneal route, in preventing the gastric damage. Both peripheral and central mechanisms seem, therefore, involved in the protective effect of opioids on rat gastric mucosa. Morphine HCl and FK 33-824 reduced significantly gastric acid secretion when administered intracerebroventricularly or intraperitoneally; in addition, a concomitant increase of prostaglandin production was observed in rat gastric mucosa after i.p. administration of both opioids. Both these events might contribute to the protective action of opioids on the stomach.

Animals↗
PubMed1983

[Biometric evaluation of the use of a battery of tests for studying the rheumatoid factor].

The research has been executed on a sample embracing 253 patients affected with rheumatid arthritis (ARA criteria), 177 patients affected with osteoarthritis and 104 healthy subjects forming the standard sample. On the serum of every subject we have used a series of five different tests in order to find the rheumatoid factor. The results we obtained have been weighed with biometrical criteria of various kinds in order to single out any possible common behaviour-pattern and to determine the tests diagnostic value as regards the considered disease. We have noticed a different result of single tests as regards the same diagnosis so we can exclude an absolute equivalence of the five tests, though for some of them there is a high mutual relation.

Arthritis, Rheumatoid↗
PubMed1983

Tubulated bodies in teleost (Pimelodus maculatus) endothelial cells.

In the present report tubulated granules are described for the first time in a freshwater teleost (Pimelodus maculatus) endothelial cells. Some ultrastructural characteristics as well as the localization and distribution suggest that tubulated bodies represent the teleost counterpart of the Weibel-Palade bodies described in other animal classes.

Animals↗
PubMed1983

Electron microscopic study of lymphocytes in a freshwater teleost (Pimelodus maculatus) epidermis.

Small lymphocytes were identified in a freshwater teleost (Pimelodus maculatus) epidermis at the ultrastructural level. Although they were the most abundant, the medium and the large lymphocytes were also present. They were found at all levels of the epidermis, specially in small spaces between the cells of the basal layer. They appeared in contact only with filament-containing cells. Intercellular junctions, however, were never observed. They were negative to the histochemical test used to detect the present of acid phosphatase.

Acid Phosphatase↗
PubMed1983

[Echopolycardiography in the detection of cardiac lesions in rheumatoid polyarthritis].

In order to verify the extent and the frequency of cardiac complications in rheumatoid arthritis (RA), the authors performed mechanophonocardiographic studies and simultaneous mono- and bi-dimensional echocardiography in 28 patients with RA, 2 men and 26 women aged between 38 and 65 (mean = 51) (history of the disease ranging from 1 to 37 years). One case showed an increase in the PEP:LVET ratio on the polycardiogram and 18 cases showed echocardiographic alterations (64.3%), in particular: pericardial effusion in 6 cases (21.4%), thickening of the epicardium and the pericardium in 4 cases (14.3%), alterations in the mitral valve (reduction in the protodiastolic closing velocity of the anterior edge of the large mitral valve) in 10 cases (35.7%) and thickening of the interventricular septum in 5 cases (17.9%). These examinations are therefore good indicators of the cardiac complications of rheumatoid disease and allow a group of patients to be identified who would not otherwise be detectable. These patients can be followed up subsequently, in the light of the positive correlation between echocardiographic alterations and the duration and severity of the disease. The authors conclude that simultaneous mono-and bi-dimensional echocardiography represents the optimal investigation for defining the nature, the severity and the frequency of rheumatoid cardiac abnormalities.

Adult↗
PubMed1982

ACTH1-24 counteracts the prolactin-releasing effect of an opioid.

The administration of the synthetic and stable opioid peptide[D-Ala2,MePhe4,Met(O)5o1]enkephalin (FK 33-824) at the dose of 0.2 mg/kg i.v. induced a rise in plasma levels of prolactin in the rat, an effect which was prevented by 1 mg/kg i.v. of the opiate antagonist naloxone. A simultaneous i.v. injection of 20 microgram/kg i.v. of ACTH1-24 significantly reduced the prolactin releasing effect of FK 33-824, therefore giving further evidence of an in vivo interaction between ACTH-related peptides and opioid peptides.

Adrenocorticotropic Hormone↗