Search PubMed⌕ Search

Biomedical subjects

S Feng

Publications and source records attributed to S Feng.

At least 181 records · Page 10Linked to original sources
PubMed1991

Wang et al. reply.

Explore the source record for details and available documents.

Journal Article↗
PubMed1991

[Estrogen receptor content of peripheral blood lymphocytes in patients with systemic lupus erythematosus].

ER content in lymphocytes of peripheral blood from 27 SLE patients and 20 healthy controls were determined by dextran-coated charcoal assay. ER content in lymphocytes of each sample was expressed by both fmol/mg of lymphocyte cytosolic protein and fmol/micrograms of lymphocyte DNA. The results showed that there was no significant difference between the ER content of lymphocytes from the controls and that from patients with SLE. But the logarithmic mean of ER content in lymphocytes, expressed by fmol/mg of cytosolic protein, in 14 patients with active SLE (0.9356 +/- 0.31) was significantly higher than that in 13 patients with inactive SLE (0.2979 +/- 0.23, P less than 0.001) and in the controls (0.6204 +/- 0.52, P less than 0.001). The normal upper limit of ER content in lymphocytes, expressed by fmol/micrograms of DNA, was 0.136. The elevated rate of ER content in lymphocytes in 14 active SLE (92.9%) was also higher than that in quieiescent patients (23.1%, P less than 0.001) and in the controls (10%, P less than 0.001). Moreover, the elevated level of ER content was found to be related to the positive antidsDNA antibody and hypocomplementemia.

Adult↗
PubMed1991

[The humoral immune response of different strains of mice after intragastrointestinal immunization with human sperm antigens].

The inbred Balb/c and C57 mice, and the outbred Swiss Webster mice were intragastrointestinally immunized with human sperm antigens. The lymphocytes from the spleen, mesenteric lymph node (MLN), Peyer's patch (PP) and uterus or epididymis were isolated and cultured. The lymphocyte-secreting antisperm IgG and IgA and the antisperm antibodies in the gut wash and serum were determined with enzyme-linked immunosorbent assay (ELISA). In the Balb/c and Swiss Webster mice, the immune responses to sperm have shown to be stronger than that in C57, stronger in female than in male. The antigenicity of sperm membrane extracts seems to be higher than that of whole sperm. Antisperm antibodies secreted by lymphocytes from the epididymis and uterus have demonstrated to be detectable. For stimulation of the local immune response, the intra-PP and intralumina immunizations are more effective than others.

Animals↗