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S F Crouse

Publications and source records attributed to S F Crouse.

21 records · Page 2Linked to original sources

Exercise modality and selected coronary risk factors: a multivariate approach.

To evaluate group differences in coronary risk which could be attributed to the modality of habitual exercise, selected physiologic and lipid indices of coronary artery disease (CAD) were measured in 57 endurance trained (ET), strength trained (ST), or sedentary (SED) men (19 per group, aged 21 to 44 yr). Initial data reduction accomplished with principle component analysis identified three factors with eigenvalues greater than one. Orthogonal rotation of the preliminary solution demonstrated that low density lipoprotein cholesterol (LDL-C), percent body fat (%BF) and VO2max, and high density lipoprotein cholesterol (HDL-C) could be used to represent Factors 1, 2, and 3, respectively. The subsequent MANOVA using these variables proved significant. Post hoc analysis via simultaneous confidence intervals indicated that LDL-C group differences were not significant. Values for %BF and HCL-C in the ST group (14.0% and 1.17 mmol.l-1, respectively) were between but did not differ significantly from respective values in the ET (11.8% and 1.34 mmol.l-1) and SED (18.7% and 1.13 mmol.l-1) groups. However, %BF and HDL-C differences between the ET and SED groups were significant. The VO2max of the ET subjects (63.2 ml.kg-1.min-1) was significantly higher than that of either the ST or SED subjects (49.5 and 46.7 ml.kg-1.min-1, respectively). These results suggest that ET is the most effective modality of exercise for CAD risk reduction while benefits derived from ST are minimal.

Adult↗

Arterial pulse wave velocity, Fourier pulsatility index, and blood lipid profiles.

Increased arterial pulse wave velocity (PWV) and decreased Doppler-shifted Fourier pulsatility index (PI) have been utilized clinically to diagnose the presence and severity of peripheral vascular disease. We have examined the relationships between these two diagnostic indices and several lipoprotein atherogenic risk factors, e.g., serum total cholesterol (TC), triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), and low-density lipo-protein-cholesterol (LDL-C) among 74 healthy male volunteers, aged 20 to 56 yr. The Doppler signal from the radial artery was digitized and processed with the Hamming window and 512-point fast Fourier transform to obtain frequency power spectra and PI index by a desktop computer. PWV was determined on the computer by dividing the distance between two pressure transducers placed over the radial and carotid arteries by the transit time difference between the maximal first derivatives (dP/dt) of the recorded arterial pulse waves. The results indicated that PI was inversely related to TC, LDL-C, and TG (r = -0.50, -0.41, -0.54, respectively, P less than 0.001), but evidenced a positive relationship with the HDL-C/TC ratio (r = 0.69, P less than 0.001). PWV was also significantly correlated to TC (r = 0.40) and TG (r = 0.42), but was inversely associated with the HDL-C/TC ratio (r = -0.45, P less than 0.001). These findings are consistent with the current theory relating lipids to the pathology of atherosclerosis.

Adult↗

Zinc ingestion and lipoprotein values in sedentary and endurance-trained men.

The finding that high doses (160 mg) of zinc lowered high-density lipoprotein-cholesterol prompted us to study the effect of low-dose zinc supplementation on lipoprotein values in sedentary and endurance-trained men. Twenty-one endurance-trained and 23 sedentary men received either placebo or 50 mg of zinc sulfate daily for eight weeks. Despite the fact that plasma zinc increased 15%, fasting plasma high-density-lipoprotein cholesterol, total cholesterol, low-density-lipoprotein cholesterol, and triglyceride levels did not change in response to zinc ingestion. We conclude that low-dose zinc supplementation does not affect lipid or lipoprotein values in either endurance-trained or sedentary men.

Adult↗