Biomedical subjects

S Ewerth

Publications and source records attributed to S Ewerth.

58 records · Page 4Linked to original sources

PubMed1978

The Mallory-Weiss syndrome. A review of 23 cases with special reference to coagulation defects.

The Mallory-Weiss syndrome is defined as bleeding from longitudinal tears in the gastro-oesophageal junction. The characteristic history consists of repeated vomiting followed by sudden haematemesis. During the past 4 1/2 years, 23 patients, 17 males and 6 females with the diagnosis of Mallory-Weiss syndrome were treated in our institution. An aetiological factor has been sought for. In a review of the case-records, we discovered that many patients had coagulation defects on admission. This was verified with extended coagulation tests at later follow-up. It is proposed that non-bleeding lacerations in the cardiac orifice in conjunction with vomiting is a common occurence, and that the Mallory-Weiss syndrome may be regarded as a complication occuring predominantly in patients with some coagulation defect.

Adult↗

PubMed1978

A retrospective study of carcinoma of the pancreas with special reference to the results of surgical treatment.

469 patients treated for carcinoma of the pancreas in the County of Stockholm in 1963--73 were analysed for mean survival time, mean hospital-stay, post-operative complications and mortality. The results of treatment with palliative biliary by-pass procedures and radical surgery were compared. The mean survival time after by-pass operation was 5,7 months and after radical surgery 12,8 months. The mean hospital-stay was 39 and 83 days respectively. The post-operative mortality after palliative biliary by-pass procedures was 16%, and the frequence of major post-operative complications 10%. The corresponding figures after radical surgery were 25% and 30% respectively. Despite the longer survival time, it is doubtful if patients benefit from radical surgery.

Adult↗

PubMedDate not supplied

Portal venous bile acids in cholesterol gallstone disease: effect of treatment with chenodeoxycholic and cholic acids.

We determined the serum concentrations of cholic, chenodeoxycholic and deoxycholic acids in portal and peripheral venous blood in 9 gallstone-free patients and 39 patients with cholesterol gallstones during standardized cholecystectomy. An accurate and specific gas chromatographic-mass spectrometric technique was used. The portal venous concentration of total bile acids was similar in gallstone-free and untreated gallstone patients (n = 20); there was no evidence of a reduced hepatic uptake of bile acids in the latter. Treatment with cholic acid (n = 10) was associated with a 70% increase in cholic acid and normal concentration of total bile acids. In chenodeoxycholic acid-treated patients (n = 9), the portal venous concentration of this bile acid was increased 3-fold; total bile acids were increased about 60%. The estimated hepatic uptake of cholic acid was slightly decreased during chenodeoxycholic acid treatment. The results indicate that neither bile acid inflow to the liver nor hepatic bile acid uptake is reduced in fasting patients with cholesterol gallstones, and treatment with chenodeoxycholic acid increases fasting inflow of bile acids to the liver. The latter may contribute to unsaturation of fasting hepatic bile during treatment with chenodeoxycholic acid.

Adult↗

PubMedDate not supplied

Rectal anatomy following Ripstein's operation for prolapse studied by cineradiography.

Eleven patients operated on for rectal prolapse, according to the method described by Ripstein, were examined pre- and postoperatively with cineradiography of the rectum. The patients were asked to fill in a questionnaire to evaluate their histories of constipation. There is no apparent anatomic explanation for postoperative constipation. One patient had a rectal stricture and another, a recurrence in the shape of an intussusception.

Adult↗