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S Enright

Publications and source records attributed to S Enright.

7 recordsLinked to original sources
PubMed1998

Inspiratory muscle function and body composition in cystic fibrosis.

Loss of body mass, which occurs in the later stages of cystic fibrosis (CF), probably affects all body compartments. We hypothesized that loss of skeletal muscle mass would include inspiratory muscles and impair their function. To test this, we determined the effect of body mass index (BMI) and lean body mass (LBM) depletion on handgrip (HG) force and inspiratory muscle function (IMF). The maximum inspiratory pressure (MIP) and the sustained maximum inspiratory pressure (SMIP) were measured with a computerized system. The relationship of IMF and reduced BMI to survival was studied in 49 patients, and a further 25 patients were studied to define the link between IMF and LBM. LBM was assessed by anthropometry. In the survival study a BMI < 20 kg/m2 was associated with a low SMIP (p < 0.001) and reduced survival, whereas MIP was relatively preserved. In the cross-sectional study SMIP (p < 0.001), MIP (p < 0.01), and HG (p < 0.01) were all reduced in the low LBM group, but not when related to total LBM. C-reactive protein and LBM were inversely related (r = -0.71, p < 0.01). Impaired IMF was chiefly a loss of sustained muscle contraction secondary to a reduced skeletal muscle mass, which may be related to pulmonary inflammation.

Adult↗
PubMed1996

Metabolic evaluation of the criteria used to fit elbow crutches by measurement of oxygen consumption.

OBJECTIVE: To investigate if elbow crutches fitted using conventional guidelines are the most metabolically efficient. DESIGN: Repeated measure connivance sample using crutch length as the independent variable. SETTING: A university exercise physiology laboratory. OTHER PARTICIPANT: Connivance sample of 10 students free from cardiovascular disease, with previous experience in crutch ambulation, and between heights of 160 and 175 cm. Four potential subjects refused to participate in the study. INTERVENTIONS: Crutch length was adjusted using conventional guidelines, and to lengths 2.5 cm above and below this setting. Oxygen consumption was measured using indirect open-circuit spirometry during the final 3 minutes of ambulation using self-selected walking speeds. MAIN OUTCOME MEASURE: Crutches adjusted to the convention setting are not the most efficient in terms of metabolic energy expenditures. RESULTS: A significant reduction in oxygen rate (p = .012), oxygen cost (p = .010), and respiratory exchange ratio (p = .009) were observed when comparing crutches adjusted to -2.5 cm of the standard height with conventional crutch height. Crutches adjusted 2.5 cm above the standard height also required less energy, but these values failed to reach any statistical significance (p > .05). CONCLUSION: The importance of fitting crutches to the correct length using conventional guidelines has not been substantiated in this study. Clinically, there should be a move away from adherence to crutch-fitting criteria and more incorporation of patient feedback to fit crutches to the optimal height. Future research should evaluate the reliability of practical clinical measures such as heart rate and perceived exertion to fit crutches to the optimal height.

Adult↗
PubMed1987

Peripheral markets.

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