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S Eiho

Publications and source records attributed to S Eiho.

14 recordsLinked to original sources

[Pathophysiological analysis of cardiac function by computer processing of echocardiograms].

Automatic image processing system has been developed for analysis of cardiac function with echocardiograms. Echograms of apical long axis view were transferred to microcomputer system and processed to display three dimensional images of left ventricular myocardium. With this technology, analysis of left ventricular wall thickness in three dimensional manner revealed pathophysiological changes in ischemic heart disease.

Coronary Disease

Left ventricular image processing of 2-D echocardiograms and 3-D reconstruction of the left ventricle.

Image processing systems of echocardiograms are discussed. The left ventricular boundary on every 2-D echocardiogram on consecutive frames digitized with an ECG (electrocardiogram) signal is traced automatically after initial manual drawing of the boundary on an end diastolic image. Various cardiac parameters are derived from these left ventricular boundaries over a cardiac cycle: volume change, regional wall motion, percentage shortening of regional wall and so on. 3-D shapes of the left ventricle and myocardium are reconstructed from several sequences of cross-sectional echo data. Cardiac parameters are also derived from these 3-D shapes and are shown on 3-D shapes as functional images of 3-D left ventricle.

Echocardiography

Left ventricular image processing.

Left ventricular image processing methods of x-ray cineangiocardiograms and ultrasound echocardiograms are discussed. 3-D reconstruction methods of the left ventricle from ultrasound echocardiograms and magnetic resonance images are also discussed. Boundary detection of the left ventricle and the quantitative analysis of the left ventricular function and wall motion are discussed. To reconstruct 3-D shapes, we need several cross sectional shapes or silhouettes of the left ventricle. Several cross sectional echo images of apical long axis view are taken by changing the angles of rotation of the probe of echo transducer around its axis. Gated multi-phase MRI method is used to obtain each 2 cross sectional images in transverse, coronal and sagittal directions. Some results of 3-D shapes of the left ventricle and myocardium reconstructed are shown and 3-D functional images which give us regional functions of the left ventricular wall on three dimensional shape are shown.

Cineangiography

Modification of pacing-induced alterations in diastolic properties of the regional myocardium by nifedipine in patients with coronary artery disease.

The effects of nifedipine on regional dysfunction during pacing-induced ischemia were studied in eight patients with coronary artery disease. Single-plane left ventriculograms were obtained using a high-fidelity micromanometer-tipped catheter in the control and post-pacing periods both before and after pretreatment with nifedipine. All patients developed typical anginal pain during pacing tachycardia before but not after pretreatment with nifedipine. After pacing, left ventricular end-diastolic pressure (EDP) increased from 10 +/- 5 (SD) mmHg to 23 +/- 9 mmHg (P less than 0.01) with enlargement of the end-diastolic volume (EDV). The ejection fraction (EF) was reduced from 66 +/- 10% to 54 +/- 13% (P less than 0.05). With nifedipine, a post-pacing increase in EDP was markedly attenuated together with a 17% reduction in left ventricular systolic pressure (P less than 0.05). The regional myocardial function was expressed by a radial coordinate system with its origin at the center of gravity of the end-diastolic contour. Two representative radial grids for normal and ischemic segments were selected. In the normal segment, the end-diastolic length (EDL) was augmented by 14% (from 26.1 +/- 5.2 mm to 29.7 +/- 6.1 mm, P less than 0.01) associated with a 23% increase in stroke excursion (P less than 0.05) with pacing stress. In the ischemic segments, EDL remained unchanged in the post-pacing beat but stroke excursion was significantly reduced (from 11.4 +/- 5.2 mm to 4.3 +/- 1.8 mm, P less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

Changes in diastolic properties of the regional myocardium during pacing-induced ischemia in human subjects.

Mechanisms related to alterations in the diastolic properties of the left ventricle during angina were studied in seven patients with coronary artery disease. Single plane left ventriculograms were obtained using a high fidelity micromanometer-tipped catheter in both the resting state and immediately after rapid cardiac pacing. In all patients, typical anginal pain developed with pacing stress. After atrial pacing, the left ventricular end-diastolic pressure increased from 10 +/- 3 to 21 +/- 7 mm Hg (+/- standard deviation) (p less than 0.005) regardless of the changes in the end-diastolic volume. The ejection fraction was reduced from 59 +/- 10 to 48 +/- 13% (p less than 0.05). The diastolic pressure-volume curves shifted upward in post-pacing beats in four patients, while in three the curves shifted more to the right. The regional myocardial function was expressed in quantitative terms by a radial coordinate system with the origin at the center of gravity of the end-diastolic silhouette. Two representative radial grids for normal and ischemic segments were selected. In the normal segment, the end-diastolic length was augmented by 15% (p less than 0.005) and was associated with a 24% increase in stroke excursion with pacing stress (p less than 0.05). The increase in diastolic pressure was accompanied by comparable increases in end-diastolic length, and the diastolic pressure-length relation moved up to the higher portion of the single curve. In the ischemic segment, the end-diastolic length remained unchanged in the post-pacing beat, but segment shortening was significantly reduced.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged

3-D heart image reconstructed from MRI data.

The gated MRI method gives us several sets of cross-sectional images on transverse, coronal, and sagittal planes of the heart in a cardiac cycle. In this paper, a method to reconstruct 3-D shapes of each part of the heart (i.e., left ventricle, left atrium, right ventricle, right atrium, aorta, and pulmonary artery), in a voxel space using these sets of cross-sectional images is proposed. The whole heart image composed of these six parts properly put together can be superimposed on the original cross-sectional images for display purposes.

Echocardiography