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Biomedical subjects

S Ehara

Publications and source records attributed to S Ehara.

At least 91 records · Page 5Linked to original sources

[Ewing sarcoma: changes after radiation and chemotherapy].

We retrospectively studied 52 cases of Ewing sarcoma to elucidate the pattern of healing and/or recurrence after radiation and chemotherapy. Persistent soft tissue mass was a sign of failure to respond to therapy. Repair or healing of lytic or blastic bone changes were slow and often minimal, and usually bone changes became gradually stable over 3 years. After bone changes became stable, localized new bone changes represented recurrence or secondary malignant neoplasms.

Adolescent↗

Sacral cysts with exophytic components. A report of two cases.

Sacral cysts are rare lesions. Two cases are presented, an aneurysmal bone cyst and a simple cyst. Simple cysts have not previously been described in the sacrum. Both cysts were asymptomatic, had similar radiographic appearances, and displayed significant exophytic components.

Adult↗

Porous-coated anatomic total hip prostheses: radiographic analysis and clinical correlation.

The radiographic changes of 46 bone-ingrowth, porous-coated anatomic total hip prostheses were reviewed and compared to the clinical outcome. The average postoperative follow-up was 32 months. The radiographic features that were assessed included subsidence; periprosthetic lucencies; periosteal, endosteal, and heterotopic new bone; loose beads; implant position; and tightness of fit. Clinical results were based on the Harris hip score. All acetabular components fared well. Three of the femoral stem components needed revision. The radiographic finding that correlated best with outcome was subsidence of more than 10 mm, especially if it continued to increase more than 1 year after surgery. Other findings related to failure were loosely placed femoral stems and the presence of loose beads. However, subsidence was such a powerful predictor of clinical outcome, and the other features were so weak, that combinations of variables did not improve the assessment of outcome. Close attention should be paid to subsidence in follow-up studies.

Chromium Alloys↗

Target pedicle of T-12: radiologic-anatomic correlation.

The authors prospectively studied 250 consecutive thoracic and lumbar spinal radiographic examinations and 56 dried skeletons to elucidate the peculiar target appearance in the pedicle of T-12 and occasionally T-11. Target pedicles were seen in 13 of the spines (23%) and in 85 of the 250 radiographic examinations (34%). Similar target pedicles were observed at T-11 in two radiographic examinations and in one spine. Anatomic correlation revealed that the inferior and lateral tubercles contribute to the ring shadow within the pedicle.

Adult↗

[Insufficiency fracture of the sacrum].

Three cases of insufficiency fracture of the sacrum are reported. Cortical disruption and linear sclerosis with or without linear fracture line at the upper sacral segment parallel to the sacroiliac joint are characteristic. Bone scintigram is suitable for screening, but plain radiographic and CT findings are diagnostic. Insufficiency fracture of the sacrum should not be confused with other conditions, such as metastatic disease.

Aged↗

[Screening for osteoporosis].

Current status of the diagnosis and treatment of postmenopausal osteoporosis is reviewed, and screening for postmenopausal osteoporosis is discussed. Although prevention and treatment of osteoporosis have been extensively investigated, further knowledge and experience may be still needed for routine clinical application.

Aging↗

Pyogenic vertebral osteomyelitis of the posterior elements.

Three cases of pyogenic vertebral osteomyelitis involving only the posterior elements are presented. This unusual location creates difficulty in distinguishing vertebral osteomyelitis from neoplasms and arthridites. All three patients had involvement of the articular facet, a helpful indication against neoplasms. However, vertebral osteomyelitis should be differentiated from erosive arthridites.

Aged↗

Giant bone island. Computed tomography findings.

Although bone island is a well-known benign skeletal entity, it may stimulate an aggressive bone forming neoplasm when it is large. Spiculated margin intermingling with thickened trabeculae together with the lack of bone destruction and soft tissue mass on computed tomography scan is diagnostic.

Adult↗

[Arthrography of temporomandibular joint; a practical approach].

A practical approach to the arthrography of the temporomandibular joint is presented. More than 80 cases have been performed in one year in our institution with the failure rate of less than 10% and very low complication rate. Advantages and disadvantages of arthrography compared to MR are discussed.

Arthrography↗

Aggressive posttraumatic osteoporosis of the humerus simulating a malignant neoplasm.

Eleven patients with an unusual, moth-eaten, destructive lesion in the humerus simulating a malignant neoplasm are presented. The radiographic changes developed over an extended period after trauma. This pattern of posttraumatic osteoporosis can easily be mistaken for a malignancy. An awareness of the entity helps one to make the correct diagnosis. Also, certain helpful hints are pointed out.

Adult↗

Magnetic resonance imaging of pyomyositis.

Pyomyositis is a relatively rare entity in temperate climates. Because of its rarity and its nonspecific clinical and radiographic findings, pyomyositis may be misdiagnosed and may cause severe morbidity and mortality. We present magnetic resonance imaging findings in two cases of pyomyositis. Magnetic resonance imaging was helpful in differentiating other pathological processes from pyomyositis, outlining the extent of involvement, and localizing the fluid collection.

Adolescent↗

Inhibitory effects of vincristine, ifosfamide and peplomycin on hormone-independent human prostatic carcinoma cell line.

The sensitivity of a hormone-independent human prostatic carcinoma cell line (PC-3) to anticancer drugs was evaluated in vitro. The anticancer drugs used were vincristine sulfate (VCR), peplomycin sulfate (PLM) and 4-hydroperoxyisophosphamide (4-HIF), i.e., an form of ifosfamide (IFOS) in vivo. The inhibitory effect of 4-HIF alone and of the combination of VCR, 4-HIF and PLM (VIP) on the cell proliferation was almost the same. Furthermore, among the 6 groups treated with 2 of the 3 drugs mentioned above the most potent inhibitory effect was obtained in the group with combined treatment of 4-HIF plus PLM.

Bleomycin↗