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Biomedical subjects

S Eguchi

Publications and source records attributed to S Eguchi.

At least 433 records · Page 24Linked to original sources
PubMed1978

[Histological appearances of cancer of the head and neck treated with pepleomycin (NK 631) (author's transl)].

Clinical findings and histopathological appearances in the patients with cancer of the head and neck treated with a new anti-tumor agent, pepleomycin, are reported. The total dosage of the new drug was within 100 mg on the average; however, the responses to chemotherapy were considerably favorable in general. Pepleomycin was markedly effective in two patients, moderately effective in seven, and ineffective in one. Microscopic evidences of regression of cancer cells were demonstrated in six surgical materials. Pepleomycin was shown to have an even more selective action on squamous cell carcinoma than bleomycin. The reactions of the surrounding tissue and skin to combination therapy, including pepleomycin, remained comparable to those to bleomycin. Side effects of the drug were slight fever and transient anorexia. No fibrosis of the lung was seen during eight months of observation.

Adult↗
PubMed1976

Simplified acoustical measurement of tubal opening.

A device is discussed in which tubal opening as one of the functions of the Eustachian tube can be measured by expressing the opening phenomena acoustically. The features of the present device are the following: introduction of the test sound of 2,000 Hz, 85 dB, SPL, directly to the tubal opening through the tubal catheter and recording of fluctuations of the sound pressure obtained at the external auditory meatus during swallowing. The results of model experiment made of resin were 85 dB, SPL, at the speaker, 76 dB, SPL, at the end of tubal catheter and 78 dB, SPL, at the external auditory meatus. In the model experiment it was also demonstrated that the height of spike waves depends on the extent of tubal opening and that the continuity of spike waves depends on the duration of tubal opening. Furthermore, in the present method, there was no so-called basic amplitude, seemingly due to the resonant effects or the direct passing sound, and the opening phenomena were correctly expressed. In the measurement on normal adults it was found that variability of the spike wave pattern between subjects was largely depending on individual subjects, and also some intra-subject variability of successively recorded spike waves on the same subject was noted. It was shown that gradual recovery of spike wave patterns occurred from initial water swallowing to successive dry swalllowing.

Acoustics↗
PubMed1976

Surgical treatment of floppy mitral valve syndrome in children.

Five children whose ages ranged from 9 to 14 years underwent operation for floppy mitral valve syndrome. The clinical course of this syndrome in young patients was characterized by exceptionally rapid deterioration in congestive heart failure after the onset of symptoms. The children responded poorly to medical treatment. Early surgical treatment should be recommended soon after the onset of congestive heart failure. Three out of 5 patients required an associated tricuspid valve replacement for a floppy tricuspid valve, whose structure showed marked myxomatous transformation. Because of the high incidence of myxomatous transformation of the tricuspid valve in children, significant tricuspid insufficiency in this syndrome should be managed by valve replacement.

Adolescent↗
PubMed1973

[Valvuloplasty].

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Adolescent↗