Search PubMed⌕ Search

Biomedical subjects

S Eguchi

Publications and source records attributed to S Eguchi.

At least 343 records · Page 19Linked to original sources
PubMed1984

Surgical implications of the pathophysiology of advanced valvular heart disease.

The pathophysiology of advanced valvular heart disease and its clinical implications were analyzed. The study was undertaken primarily on 153 recent patients with implantation of central flow valves. The operative mortality rate was 3.9%, with deaths except one related to LOS. There was a higher incidence of LOS in left ventricular volume-overloaded hearts, and a much higher incidence in patients associated with TR: 70% of TR cases with RVEDP higher than 15 mmHg developed LOS. Cardiac contractile reserve proved to be useful index for predicting immediate postoperative and long-term results; less favorable results were indicated in patients with PWE below 10 mm even after epinephrine infusion. In volume-overloaded hearts, the muscle cell diameter of the left ventricle increased proportionally to the dimension of the left ventricle, with interstitial fibrosis representing irreversible morphological change. Patients with a prolonged indocyanine green disappearance rate showed fibrosis of the liver and were complicated more frequently by LOS, hepatic and renal disturbance and increased mortality. Patients with cardiac cachexia were liable to develop LOS postoperatively, and preoperative GIK therapy appeared to be effective in improving depressed metabolism and hemodynamics, except in patients with severe TR.

Adult↗
PubMed1984

Successful surgical repair of left ventricular rupture after acute myocardial infarction.

A 61-year-old man with impending myocardial infarction was admitted and treated by percutaneous transluminal coronary recanalization (PTCR) therapy using Urokinase. Patient's symptoms subsided and his general condition maintained stable until the fifth hospital day, when he developed the signs of cardiac rupture. He was operated upon immediately, and the left ventricular rupture was confirmed and repaired successfully. Patient recovered from the surgery well. This report describes the rare successful surgical case of cardiac rupture secondary to acute myocardial infarction in Japan.

Cardiac Catheterization↗
PubMed1984

Duplication of the tricuspid valve with Ebstein anomaly.

Duplication of the tricuspid valve is a rare congenital cardiac anomaly. We experienced one infant case with Ebstein anomaly, who died at seven months of age. At autopsy, the clinical diagnosis was confirmed, and also the patient was found to have double tricuspid valve orifices, each of which were accompanied by subvalvular tension apparatuses. Tricuspid valve leaflets seen in Ebstein anomaly are known to have fenestrations as accessory orifices for some instances, but this case is unique and interesting in that each valve orifice has well-developed chordae tendinae and papillary muscles below it.

Ebstein Anomaly↗
PubMed1984

Development of left ventricular muscle in tetralogy of Fallot.

Age-related changes of the muscle fiber diameter of the left ventricle were studied in 20 autopsied specimens of tetralogy of Fallot (TOF) and in 34 normal autopsied hearts. According to the amount of pulmonary blood flow, two groups were defined: In Group 1, TOF with a markedly decreased pulmonary blood flow. In Group 2, TOF with a moderately decreased pulmonary blood flow. In Group 1, the muscle fiber diameter was nearly normal at birth, but increased slightly and remained constant after one year, so that it was significantly less than normal. Moreover, histological observation revealed underdevelopment of the left ventricular muscle fibers in this group. In Group 2, the diameter increased with age in a manner similar to normal and, histologically, the muscle fibers were not different from normal ones except for those in one heart with left ventricular hypertrophy. The growth of muscle fibers in the left ventricle seems to depend on the volume of pulmonary blood flow, or the left ventricular inflow volume. If the left ventricular functional capacity correlates with the growth of muscle fibers, left ventricular dysfunction after the corrective operation may originate in the underdevelopment of muscle fibers. Surgical intervention is advisable before the retardation of muscle fiber growth has become apparent.

Age Factors↗
PubMed1984

[A comparison of the penetration characteristics of latamoxef and cephalothin into the right atrial appendage and pericardial fluid of adult patients undergoing open-heart surgery].

A comparative study of the serum, atrial muscle, and pericardial fluid concentrations of latamoxef (LMOX) and cephalothin (CET) was performed in 18 adult patients having cardiac surgery. Patients were randomly assigned to receive either a single dose of CET 30 mg/kg, LMOX 30 mg/kg, or LMOX 20 mg/kg. Each drug was administered intravenously soon after anesthetic maintenance was achieved. After each drug administration, serum samples were obtained at various time intervals before, during, and after extracorporeal circulation (ECC), and assayed for CET and LMOX concentration. A sample of pericardial fluid was collected immediately after the pericardium was opened. The right atrial appendage tissue samples were obtained at the time of heart cannulation. The pharmacokinetics and penetration characteristics of each drug were analysed by the method of two-compartment model. Serum concentrations of CET following a single intravenous injection of 30 mg/kg were the high values, 172.4 +/- 35.6 micrograms/ml at 5 minutes, and 92.9 +/- 33.8 micrograms/ml at 15 minutes after injection. The initial (before bypass) half-life was 0.22 +/- 0.11 hour (13.1 minutes) while half-lives during and after ECC were prolonged significantly. In the cases of CET group, the myocardial tissue concentration value of 4.86 micrograms/g was obtained in only 1 case. The mean pericardial fluid concentration was 4.69 +/- 3.35 micrograms/ml at 5 to 30 minutes after injection. Serum concentration of LMOX following a injection of 30 mg/kg were 253.6 +/- 67.4 micrograms/ml at 5 minutes, and 176.3 +/- 64.1 micrograms/ml at 15 minutes after injection.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1984

[Review of intra-arterial infusion-radiation therapy for lingual cancer].

Since 1974, we have performed intra-arterial infusion combined with radiation therapy in 137 cases of malignant tumor of the head and neck region. Of these 31 cases of lingual cancer are reviewed in the present paper. The cases were divided, according to the kind of infusional agent administered, into the following groups: BUdR X 5-FU (BAR), 13 cases and BUdR, 18 cases. Instances of death occurring in patients to which anti-cancer agents were applied were as follow: BAR, 8 cases (2 local recurrence, 1 lymph node metastasis, 3 unknown and 2 other causes) BUdR, 8 cases (2 local recurrence, 3 lymph node metastasis, 2 pulmonary metastasis, 1 unknown). Cases of death classified by stages included: (I) 2/6, (II) 4/10, (III) 8/13 and (IV 2/2. The shortest period of observation was 2 years and the longest 10. One of the 15 surviving cases has undergone hemiglossectomy due to recurrence, but the remaining 14 have not received any surgical treatment.

Adult↗
PubMed1983

Usefulness of two-dimensional echocardiography for diagnosis of the sites of origin in myxoma.

Three patients with atrial myxoma, two in the left atrium and one in the right were studied using two-dimensional echocardiography. An analysis by four cross sections, long and short axis, subcostal and four chamber views of the left ventricle showed that the stalk of one left atrial myxoma adhered to the anterior commissure, the other to the left atrial wall underlying on the aortic posterior wall, and that of right myxoma to the free wall of the right atrium. The myxomas were successfully removed by surgical intervention in all cases, where the sites of stalk were verified to be identical with those diagnosed by echocardiography.

Adult↗
PubMed1983

[Case of immunoblastic sarcoma (IBS)].

A patient with immunoblastic lymphadenopaty which evolved into immunoblastic sarcoma is reported. A 48-year-old female was admitted to our department because of cough and fever. A diagnosis of immunoblastic lymphadenopathy had been made two years before the present admission. Physical examination revealed generalized lymphadenopathy. Chest radiograms showed a left hilar mass. The pulmonary tumor and enlarged lymphnodes were treated by irradiation. Although there was marked improvement at first, she experienced several relapses. One year after the admission, chest radiograms showed multiple pulmonary lesions. She developed pancytopenia and bone metastases. At autopsy, the lymphnodes showed histological evidence of immunoblastic sarcoma; a pulmonary lesion showed immunoblastic lymphadenopathy.

Anemia, Hemolytic, Autoimmune↗