Epidural hematoma from lumbar puncture.
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Biomedical subjects
Publications and source records attributed to S E Warren.
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Fifty-five patients with stage II and III bronchogenic carcinoma were randomized into one group of 21 treated conventionally, and another group of 34 additionally vaccinated with BCG. Vaccinated patients survived, on average, 11 weeks longer than controls. A lag of about six months existed before consistent differences became apparent.
Acute renal failure in a diabetic patient following contrast injection for computerized tomography is discussed. Like a variety of serious complications associated with contrast media, dye-induced renal failure is an important iatrogenic complication to which the diabetic population may be unusually susceptible.
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A single left coronary artery was found in an asymptomatic 21-year-old man who initially had electrocardiographic and vectorcardiographic evidence of anterolateral myocardial infarction. The single left coronary artery, which supplied the distribution of both the left and right coronary arteries, was free of disease at catheterization. There has been no previous association of a normal single left coronary artery and anterior myocardial infarction. Patients with the finding of a single coronary artery should be watched closely, as this may represent a potentially fatal condition.
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Both sodium restriction and weight loss without alterations in sodium balance have reportedly resulted in blood pressure decrements in hypertensive man. The antihypertensive mechanism of short-term (5-day) sodium restriction was investigated in 38 essential hypertensive adults. The small decrement (6 mm Hg) that occurred in mean arterial pressure during low- as opposed to high-salt intake (35 and 177 mEq/day, respectively) correlated best with plasma volume contraction. Baroreflex sensitivity was unchanged during salt deprivation, while renal hemodynamics actually deteriorated. Inasmuch as rigorous sodium deprivation would result in (1) questionable compliance and (2) a small decrement in arterial pressure at the expense of (3) impaired renal perfusion, the merits of such a strategy as first-line therapy of hypertension should be questioned and confirmatory long-term studies initiated. It should be reiterated that these are short-term findings whose interpretation may not pertain to a period longer than a few days.
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A method for measuring the ascending aortic cross-sectional dimension is reported. First-pass radionuclide angiocardiography was performed in 53 patients with various cardiac diseases. The number of pixels from superior vena cava/right atrium junction to the main pulmonary artery were counted horizontally and converted to distance in centimeters. Aortic root size was also measured in these patients by M-mode echocardiography performed within 6 months of the radionuclide study. The two methods were compared by regression analysis. The correlation coefficient between the methods was 0.76, and the standard deviation of the regression was 0.23 cm. This radionuclide method has an accuracy which can be clinically useful for size assessment of the ascending aorta.