Search PubMed⌕ Search

Biomedical subjects

S E Reid

Publications and source records attributed to S E Reid.

34 records · Page 2Linked to original sources

Bilateral adrenal hemorrhage as a complication of intravenous ACTH infusion in two patients with inflammatory bowel disease.

We report two patients with inflammatory bowel disease in whom intravenous corticotropin therapy was complicated by bilateral adrenal hemorrhage. In one, the initial presentation was acute and unilateral, simulating colonic perforation and/or abscess. The diagnosis was made only at exploratory laparotomy. In the second patient, the presentation was subacute; multiple episodes of adrenal hemorrhage occurred subsequent to the course of corticotropin, and ultimately, hypoadrenalinism developed. Pertinent clinical and computed tomographic findings are reviewed.

Adrenal Gland Diseases↗

Oxytocin induced second trimester uterine rupture.

A case of oxytocin induced rupture of an unscarred uterus during the second trimester is presented. While rupture of the uterus by oxytocic agents in the second trimester has previously been documented, this case is unusual in that fetal parts were palpable through the cervical os, delaying diagnosis and definitive management. Digital palpation of fetal parts through the cervix does not preclude the diagnosis of fetal extrusion secondary to uterine rupture.

Adult↗

Pyomyositis: a differential diagnosis from sarcoma.

A case of pyomyositis, a deep muscle abscess, presenting as a soft tissue sarcoma is reported. Although common in the tropics, this disease is quite rare in the United States. The presentation, diagnosis, and treatment of the problem are discussed and reviewed.

Abscess↗

Problems in the diagnosis of ectopic pregnancy: the pseudogestational sac.

The term pseudogestational sac was first suggested by Mueller in 1979. It was applied to the echo pattern which he noted on ultrasonic examination of 2 patients with ectopic pregnancy. He suggested that the echo pattern, which can easily be misinterpreted as a gestational sac, is produced by the decidual cast with blood contained in its centre. During the past 3 years, 6 cases of pseudogestational sacs have been recorded at K.E.M.H. In 3 of these the possibility of ectopic pregnancy was suggested by the ultrasonologist because of suspicious extra-uterine echo patterns associated with the pseudogestational sac. In the remaining 3 patients the ultrasonologist reported that there was an intrauterine pregnancy, an error which influenced clinical management. These 3 cases are summarized below.

Adult↗

Advances in sports medicine. Prevention of head and neck injuries in football.

Statistics on catastrophic head and neck injuries in football provide a more realistic indication of the incidence of serious injuries occurring on the football field than do the fatality figures. These statistics, however, provide no clues for preventing such injuries. Moreover, research using head models, anesthetized animals, cadaveric heads, and estimates of brain tolerance to impact based on studies of actual injuries to the heads of humans has produced conflicting data with respect to the goal of improving the safety record of the sport. To reconcile the data and to provide some solutions to the problem of serious injuries on the playing field, we reviewed the data collected in the laboratory and correlated it with the information obtained from telemetry studies. As a result of combining these two data sources, we concluded that injuries on the playing field occur at either end of the spectrum of offered resistance: when too much resistance is offered and when little or no resistance is offered. We demonstrated that, by avoiding either of these extremes, serious injuries to the head and neck can be reduced considerably. Finally, we discussed the importance of preprogrammed responses by the experienced, well-conditioned athlete. These allow the athlete to avoid either extreme of resistance and, thereby, protect him from injury. Clearly, the data obtained from laboratory and telemetry studies will prove instrumental in effecting changes in the sport of football. As a result of these studies, we can hope for alterations in the design of the helmet, enlightened coaching techniques, and rule revisions--all of which will serve to make football a safe sport.

Adult↗

Neck muscle resistance to head impact.

The role of neck muscles in the body's response to the "whiplash" type of motion which occurs during frontal impact has been studied. This type of motion was simulated by a sudden backward pull of a subject's head. Head and neck response to low-level acceleration has been researched by recording the externally applied force, the head accelerations in the median sagittal plane, and the electrical activity in the sternomastoid muscle (EMG) as functions of time. The resultant acceleration-time curve and recorded EMG have been analyzed, with numerical values of applied resistance to the external force recorded. An analog computer model was built incorporating resistance developed by two main variable: 1) the elasticity coefficient; 2) the active damping factor. Together these two variables, combined with a resistance function, enable us to measure the resistance of the head/neck response. Using this model, variations in magnitude of these two components were studied under six varying conditions of impact: 1) length of warning time; 2) type of instruction given to the subject; 3) amount of previous experience on the part of the subject in similar situations; 4) anticipation of impact by the subject; 5) magnitude and kind of impact; 6) presence or absence of a preload.

Acceleration↗

Football, neck muscles and head impact.

Any blow to the head may be injurious because it is the manner of response to the blow rather than the blow itself that produces the injury potential. Impacts to inanimate objects or to the heads of anesthetized animals produce data that are simplified by the fact that the involved mass is a constant, and the contact time is consistently negligible. On the football field, all the muscles in the body of the player are tensed at the snap of the ball, and the involved mass varies widely during the resulting prolonged contact time. This causes variable accelerations, variable forces and variable velocity changes as well as a varying mass which can only be measured, therefore, according to the impulse momentum theorem, Ft = deltaMV.

Athletic Injuries↗

Physiologic response to impact.

The football field, an ideal setting for research in trauma by radiotelemetry, has allowed collection of data on man's response to impact. The physiologic response adds a new dimension to the measurement of impact tolerance. The present study has demonstrated the protective response of the athlete and explains how he is able to dissipate forty times more kinetic energy than his helmet is capable of absorbing.

Adaptation, Physiological↗

Fetal and maternal Doppler flow velocity waveforms in normal sheep pregnancy.

Abnormalities in placental vascular resistance have been shown to have an important association with intrauterine growth retardation in both human and sheep pregnancies. In this study we have assessed impedance to blood flow through the ovine placental circulation by Doppler flow velocity waveform analysis. As gestation advanced from 66 to 136 days, a significant decrease in impedance to flow was observed in both umbilical and maternal placental arteries. The greatest decrease in impedance was observed between 66 and 109 days' gestation in umbilical arteries and between 66 and 80 days' gestation in maternal placental arteries. In these normal pregnancies, no significant correlations could be found between Doppler flow velocity waveform analyses and fetal or placental growth. We conclude that Doppler flow velocity waveform analysis is a valuable and non-invasive method to assess impedance to blood flow through the placental circulation in pregnant sheep.

Animals↗