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Biomedical subjects

S E Mitchell

Publications and source records attributed to S E Mitchell.

At least 73 records · Page 4Linked to original sources

Right-sided varicocele: technique and clinical results of balloon embolotherapy from the femoral approach.

Among 227 patients undergoing outpatient balloon embolotherapy for varicocele, venography of the right internal spermatic vein (ISV) was attempted in 48. A percutaneous technique from the right femoral vein was used for all patients. The right ISV was successfully occluded with detachable balloons in 41 of 46 (89%), while in five (11%), the right ISV could not be embolized. A competent valve was found in two patients. The right ISV alone was embolized in ten patients: one had a solitary right varicocele, six had left varicoceles but competent valves in the left ISV, and three had recurrent left varicoceles after successful left ISV occlusion. Bilateral ISV embolization was achieved in 31 patients. Long-term follow-up study was available for 25 patients; 12 couples (48%) achieved a pregnancy. Percutaneous balloon occlusion of right varicoceles is a safe, effective outpatient technique.

Angioplasty, Balloon↗

In situ saphenous vein bypass grafts: angiographic evaluation and interventional repair of complications.

In situ saphenous vein grafts are being used with increasing frequency for bypass procedures involving the femoral and popliteal arteries. Complications of these procedures include anastomotic stenoses and persistent arteriovenous fistulae that may result in failure of the graft. Balloon angioplasty and embolotherapy with detachable balloons were employed successfully in three or four recent cases of patients with complications from in situ grafts. Tailored angiography is essential for evaluating in situ grafts, and interventional techniques are extremely useful for managing complications.

Aged↗

Vessel sizing wire: accurate vessel measurement using digital subtraction arteriography.

A simple method of measuring vessel diameters using intraarterial digital subtraction angiography has been designed. With a catheter in place within the vessel of interest, a segmented guide wire with known dimensions is advanced into the catheter in the area to be measured. We have used the method successfully for balloon angioplasty as well as balloon embolization.

Angiography↗

Long-term results of superficial femoral artery angioplasty.

Short-term results of superficial femoral artery and popliteal percutaneous transluminal angioplasty have been good, but long-term results and factors influencing long-term patency are less commonly reported. One hundred thirty-seven superficial femoral artery angioplasties with follow-up for 54 months were reviewed. The 4-year patency for stenoses was 61% and for occlusions was 68%. If the initial result was clinically successful, the 4-year patency was not influenced by the quality or patency of runoff or by the length of the occlusion. Nineteen patients returned for redilatation, eight of whom had developed new lesions. Patency was adversely affected in patients with diabetes or with long-segment stenoses. Modifications of equipment and technique that may improve long-term patency rates are discussed.

Angioplasty, Balloon↗

Percutaneous transluminal angioplasty and transaxillary first rib resection. A multidisciplinary approach to the thoracic outlet syndrome.

A 33-year-old man with the thoracic outlet syndrome complicated by recurrent upper extremity deep venous thrombosis underwent venographic and dynamic venous pressure studies that suggested both extrinsic and intrinsic venous obstruction. The patient was treated with transaxillary first rib resection and percutaneous transluminal angioplasty of the involved subclavian vein stenosis and is symptom-free at 16 months follow-up. To our knowledge this is the first case in which such a multidisciplinary approach to the thoracic outlet syndrome has been performed.

Adult↗

Percutaneous displacement of calyceal calculi. Adjunct to percutaneous nephrolithotripsy.

Two cases are presented of successful percutaneous removal of adherent calyceal calculi which were initially inaccessible for removal with the rigid nephroscope. In each case, the calculus was dislodged from the calyceal wall by the direct force of a needle introduced percutaneously against the stone. In the first patient, a wedged calyceal calculus was dislodged percutaneously and manipulated into the renal pelvis the day before extraction using the rigid nephroscope. In the second patient, the adherent calculus was dislodged percutaneously at the same time of endoscopic removal. In both patients, prior carbon dioxide pyelography was helpful in determining the optimum direction for advancing the needle against the calculus. Percutaneous stone dislodgement technique is a useful adjunct to percutaneous nephroscopic removal of the difficult calyceal calculus.

Endoscopy↗

Inpatient admissions for interventional radiology: philosophy of patient management.

As an alternative to performing interventional radiology on inpatients under the care of internists and surgeons, the authors have established a cardiovascular radiology admitting service for well-screened, elective patients. The patients are admitted under the care of a cardiovascular radiology fellow and a staff physician. From April 1982 to December 1983, 133 patients were admitted to the service. Patients are cared for in a surgical ward or in an intermediate unit, as determined by the clinical situation. Advantages of this approach include a broader patient referral base, improved rapport with clinical colleagues and patients, improved follow-up data, and rapid evaluation and treatment, resulting in short hospital stays. The major disadvantages involve the commitment of time and staff necessary to provide quality care. The concept of the interventional radiologist in the role of admitting physician has important implications in terms of negotiations for additional financial compensation, commensurate with the skill and time required for performing these procedures and caring for the patient.

Angioplasty, Balloon↗

Nonoperative management of benign postoperative biliary strictures.

Selected benign biliary strictures can be treated safely and successfully by percutaneous balloon dilatation. Primary biliary strictures appear to be less responsive to balloon dilatation alone and require stenting with large catheters (16-20 F) for several months to permit scarring around the catheter. A long period of healing around such a large-bore stent is crucial to the success of such treatment. The most important physiologic indicators for successful dilatation are a long period of stricture challenge with a catheter placed proximal to the dilated segment to allow bile to drain internally across the previously strictured segment, and a near anatomic result as demonstrated by cholangiogram.

Adolescent↗

Biliary catheter drainage complicated by hemobilia: treatment by balloon embolotherapy.

Seventeen patients experienced severe hemobilia following percutaneous (nine patients) or surgical (eight patients) placement of biliary drainage catheters. Fourteen patients bled early after catheter placement (0.5-32 weeks; mean, 5.4 weeks) and three bled late during long-term biliary drainage (1.1-3.6 years; mean, 2 years). Hepatic angiography demonstrated the source of bleeding in 15 (88%) patients (hepatic artery pseudoaneurysm in ten, hepatic artery-portal vein fistula in four, varix along the tube tract in one) but showed no source of bleeding in two. Thirteen patients with hemobilia were treated with embolotherapy, using detachable balloons in 12. The advantages of this technique included the ability to flow-direct the balloon without selective catheterization; the ability to test-inflate the balloon at the site of the aneurysm or fistula during angiographic study and adjust its position before detachment; and preservation of the hepatic artery proximal and distal to the inflated balloon, thus preserving hepatic function following embolization.

Adult↗

Percutaneous transhepatic biliary drainage for bile leaks and fistulas.

Percutaneous transhepatic cholangiography and biliary drainage were performed in 12 patients with major injuries to the bile ducts manifested by biliary leaks and fistulas. Eleven of the 12 patients had had inadvertent biliary trauma during surgery. In six patients, the biliary leaks sealed with percutaneous drainage. In other patients requiring definitive surgical procedures on the biliary tract, initial percutaneous drainage allowed these procedures to be delayed until the patients' clinical condition improved. Percutaneous biliary drainage is an important adjunct to the management of patients with traumatic extravasation of bile into the peritoneal cavity or biliary-cutaneous fistula.

Abscess↗

Comparative susceptibilities of Anopheles quadrimaculatus mutants to Plasmodium yoelii.

Four homozygous mutant stocks and a wild-type stock (ORLANDO) of Anopheles quadrimaculatus were compared for susceptibility to Plasmodium yoelii. The mutant stocks, rose eye (ro) and red stripe (strd), had the same level of susceptibility as the control stock (ORLANDO), but Q2 (homozygous for brown body and nonstripe) and rose eye Q2 (roQ2), were significantly less susceptible. Body size of the adult mosquitoes had no effect on susceptibility.

Animals↗

Intraarterial digital subtraction angiography in diagnostic arteriography.

Intraarterial digital subtraction angiography (DSA) was performed in 133 diagnostic arteriographic procedures during a 10-month period. The increased contrast resolution of DSA permitted the use of a dilute (15%) contrast material. A significant reduction in contrast material dose compared with conventional film-screen arteriography and intravenous DSA was thus achieved. This was especially advantageous in patients with diminished renal function. The dilute contrast material also resulted in less patient discomfort. Subtracted images were available immediately on cathode ray tube display, resulting in faster procedures, and a considerable saving in film cost compared with conventional arteriography. It is concluded that intraarterial DSA is a useful technique that may replace conventional film-screen arteriography in many applications.

Angiography↗

Iliac artery occlusion: management with intrathrombus streptokinase infusion and angioplasty.

Chronic and acute unilateral iliac artery occlusions were successfully treated in 7 of 8 patients using low-dose intrathrombus streptokinase infusions ranging from 6 to 43 hours in combination with percutaneous transluminal angioplasty. Angioplasty of an underlying stenosis was performed as soon as clot lysis was maximal and an underlying stenosis was demonstrated. Long-term follow-up to date has been excellent. This approach to unilateral iliac occlusion appears to be safer than previously reported angioplasty of iliac artery occlusion.

Adult↗

Percutaneous transluminal balloon valvuloplasty for pulmonary valve stenosis.

Transluminal balloon valvuloplasty was used to treat congenital pulmonary valve stenosis in 20 patients. Follow-up cardiac catheterization was performed in 11 patients at intervals of from 2 to 12 months after the procedure. Peak systolic pressure gradient across the pulmonic valve decreased from 68 +/- 27 to 23 +/- 5 mm Hg (p less than .001) after valvuloplasty. There were no complications. Follow-up catheterization demonstrated persistent relief of right ventricular hypertension in the patients with typical pulmonary valve stenosis.

Adolescent↗

Digital subtraction angiography in interventional radiology.

Intraarterial digital subtraction angiography (DSA) was used an an adjunct to interventional vascular procedures (embolotherapy and transluminal angioplasty) in 56 patients. The advantages of intraarterial DSA include improved contrast resolution, instantaneous subtraction capability, and immediate image availability. A considerable reduction in contrast dose and concentration, procedure time, and patient discomfort can be expected when interventional vascular procedures are performed with the assistance of intraarterial DSA.

Angiography↗