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S Dokumov

Publications and source records attributed to S Dokumov.

52 records · Page 3Linked to original sources
PubMedDate not supplied

[The functional state of the adrenal cortex in patients with gonadal dysgenesis and a female phenotype].

Excretion of 17-KS and 17-OCS was studied in the urine of 86 patients with various cytogenetic variants of gonad dysgenesis of a female phenotype under basic conditions and after ACTH stimulation; in 10 patients endogenous hypophyseal ACTH reserve after block of the adrenal cortex by metopyrone was investigated as well. A conclusion was drawn on the presence in these patients of differnet types of deviations of the adrenal gland function. In some of the cases there is a primary "global" or dissociated injury of the adrenal cortex, apparently directly associated with gonosome anomaly; in other cases--with disturbed regulation of ACTH secretion.

17-Hydroxycorticosteroids↗
PubMedDate not supplied

[True agonadism].

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Adult↗
PubMedDate not supplied

Gonadotropin secretion in patients with gonadal dysgenesis.

Plasma FSH and LH levels were investigated by the radioimmunological method of Burr et al. [1] in 35 patients with gonadal dysgenesis. In addition ten healthy, normally menstruating women were examined as controls. Plasma FSH levels were significantly elevated in the patients with gonadal dysgenesis, while LH concentration disclosed no characteristic alteration. There was no specific correlation between the plasma FSH and LH levels. The data obtained add further support to the idea that gonadotropin synthesis and release may be differentially affected by the gonadal steroids.

Adolescent↗