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Biomedical subjects

S DRAY

Publications and source records attributed to S DRAY.

At least 19 recordsLinked to original sources

LINKAGE IN CONTROL OF ALLOTYPIC SPECIFICITIES ON TWO DIFFERENT GAMMA-G-IMMUNOGLOBULINS.

Allotypic specificities were identified on two different myeloma proteins and the corresponding normal gammaG-immunoglobulins of BALB/c mice. When the sera of F(2) progeny from a cross between BALB/c mice having the a1 allotype and AL mice having the a4 allotype were tested for these specificities, it was found that the two allotypic specificities of the BALB/c mice were either both present (87 mice) or both absent (36 mice), an indication of linkage in their genetic control.

Animals↗

Genetic control of two gamma-globulin isoantigenic sites in domestic rabbits.

Results of immunochemical analysis of sera from 335 offspring of 81 litters of rabbits are consistent with the hypothesis that the isoantigenic sites, RGG-I and RGG-II, of the gamma-globulins are controlled by a single allelic pair of autosomal genes with both specificities exhibited by the heterozygote. The three genotypes may be designated gamma(I)/gamma(I), gamma(II)/gamma(II), and gamma(I)/gamma(II).

Animals↗