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Biomedical subjects

S D Vincent

Publications and source records attributed to S D Vincent.

46 records · Page 3Linked to original sources
PubMed1988

Incidence and characterization of temporomandibular joint sounds in adults.

The findings from this study indicate that some signs and symptoms associated with TM dysfunction are relatively common clinical observations in adults, and that they might or might not be associated with pain, decreased joint mobility, and most importantly, might not be progressive. The rationale for instituting therapy in patients with TM noises who are asymptomatic and have freedom of mandibular movements needs to be evaluated in relation to these findings.

Adolescent↗
PubMed1987

Central granular cell odontogenic fibroma.

First described in 1962, the so-called granular cell ameloblastic fibroma has been a rarely reported benign odontogenic tumor. On reviewing the literature, we have identified eight previously reported cases. All cases involved well-circumscribed radiolucencies in women who ranged in age from 53 to 65 years. Seven lesions occurred in the posterior body of the mandible, and one occurred in the premolar region of the maxilla. All lesions were treated with surgical excision, and no recurrences were identified during follow-up periods of 6 to 144 months. Two additional cases also appear to represent instances of this neoplasm, which bring the total number identified to ten. We describe the clinical, radiographic, and histopathologic features of two additional cases and suggest reasons the tumor should be referred to as central odontogenic fibroma, granular cell variant.

Adult↗
PubMed1987

Nodular hidradenoma: an eccrine sweat gland analog of pleomorphic adenomas of salivary gland origin.

A tumor of eccrine sweat gland origin is described that bears a striking resemblance to pleomorphic adenomas of salivary gland. Upon closer examination, the tumor contained areas of apocrine decapitation secretory activity, primitive hair follicles, and melanin pigmentation, indicating cutaneous rather than mucosal origin. Six-month follow-up examination has revealed no evidence of recurrence.

Adenoma, Pleomorphic↗
PubMed1986

Carcinoma cells may modulate their supporting connective tissue.

The patterns of growth of two chemically-induced murine squamous cell carcinoma cell lines and their effect on a deep connective tissue graft bed were examined in syngeneic C57Bl/6 mice. The two cell lines displayed markedly different patterns of histo-differentiation but in vivo the poorly-differentiated line (FS) gave rise to tumours with much lower inocula than the well-differentiated cell line (A5). To evaluate the effect of the tumour cells on the graft bed a bioassay involving transplantation of epidermal sheets was used. Whereas the pretreatment of the deep connective tissue graft bed with the FS cell line facilitated the subsequent growth of the epidermal sheets, beds treated with the A5 cell line, lethally irradiated tumour cells or receiving no treatment failed to support continued growth of normal epidermis. We suggest that this ability of a carcinoma cell line to modify the connective tissue may facilitate the establishment of metastatic deposits.

Animals↗
PubMed1983

Mandibular abnormalities in neurofibromatosis. Case report and literature review.

A patient with von Recklinghausen's neurofibromatosis that was undiagnosed until the sixth decade of life is discussed. He came for evaluation and treatment of multiple radiolucent lesions, bilaterally distributed throughout the mandible. Histologic examination of a cutaneous nodule, as well as of the intrabony radiolucencies, confirmed the diagnosis of neurofibromatosis. Examination of the intrabony radiolucencies revealed fibrous connective tissue with an inflammatory cell infiltrate. Family history revealed marked variation in expression of the clinical features of the disease.

Humans↗