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Biomedical subjects

S D Singh

Publications and source records attributed to S D Singh.

At least 55 records · Page 3Linked to original sources
PubMed1983

Cervical lymph node metastases: the significance of the level of the lymph node.

Two thousand and fifty-eight patients with squamous carcinoma of the head and neck are described. Thirty-five per cent of these patients had a node in the neck at the time of presentation. The level of the node was dictated by the primary tumour: other factors such as T or N status were not significant predictors of node level. Node level was a highly significant predictor of survival, together with age, general condition, node status and site the primary tumour. The 5-year survival for nodes at Level I (submandibular) nodes was 34%, and only 4% for nodes at Level IV.

Aged↗
PubMed1982

Management of post-cricoid carcinoma.

This paper discusses the results of treatment of post-cricoid carcinoma based on a personal series of 141 patients. The following conclusions can be drawn: small tumours with no clinical evidence of cervical lymph node metastasis should almost certainly be treated with radiotherapy, which gives a 5-year survival of approximately 35%. Surgery for recurrent disease after radiotherapy if fraught with complications, and satisfactory salvage is seldom possible. Surgery for larger tumours and those associated with neck node metastases has a lower (20%) 5-year survival with a high incidence of complications. The main problem after pharyngolaryngectomy is replacement of the pharynx. There is no evidence that any one of the methods in common use (skin flaps, transposition of the colon or stomach) is superior to any other.

Adult↗
PubMed1982

The management of glottic T3 carcinoma.

In the treatment of glottic T3 carcinoma there are four possible methods (1) primary radical surgery, (2) primary radical radiotherapy, (3) radical surgery with preoperative irradiation or (4) partial surgery. This study shows that patients treated primarily by surgery achieve worse results than those treated by radiotherapy.

Adult↗
PubMed1978

A genetic survey in the Bhil tribe of Madhya Pradesh, Central India.

Examination of blood groups, plasma proteins and red cell enzyme types (23 loci), in a sample of 145 Bhils, a tribal group of Madhya Pradesh, Central India, demonstrates their genetic uniqueness. They differ in a number of systems from the nearby nontribal groups both of Hindus and Muslims. The results suggest that the Bhil frequencies include vestiges of the ancestral genepool of a more widespread aboriginal population whose influence is detectable in the gene frequencies of some other populations in India.

Adenosine Deaminase↗
PubMed1977

Hypoplasia of the nasal bones.

A case of nasal bone hypoplasia is presented. It resulted in mild respiratory obstruction due to collapse of overlying soft tissue on inspiration. A brief note on the growth of the nasal bones is made. All previously reported cases, which could be found in the literature, on absence or hypoplasia of nasal bones have been reviewed. A number of possible conditions which could result in loss of the nasal bone is discussed.

Adolescent↗
PubMed1976

Fine structure of Plasmodium gallinaceum in embryonic and neonate chicks.

The erythrocytic stages of Plasmdoium gallinaceum in chicken embryos injected with parasited blood either from a syringe-passaged infection in chickens or from a chicken infected with sporozoites were characterized by abnormal structure. Particularly evident were large, unstained vacuoles within the cytoplasm; these occurred with greatest frequency in schizonts. The presence of myelin bodies within these vacuoles was revealed by transmission electron microscopy; abnormal cytokinesis and aberrant merozoites provided additional evidence of the parasite's inability to develop naturally within the milieu of the embryonic erythrocytes. Fifty-five passages were necessary to restore normal structure of the parasites in embryos, while only 5 passages were required for such restoration in neonate chicks. The probable adaptation of the parasite to the proportions of hemoglobin of the adult chicken may be responsible for the abnormal growth in the immature host.

Animals↗