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Biomedical subjects

S D Devine

Publications and source records attributed to S D Devine.

3 recordsLinked to original sources

Acetabular augmentation in primary and revision total hip arthroplasty with cementless prostheses.

Twenty-four consecutive cementless hip arthroplasties (13 autografts and 11 allografts) have been done in which large bone grafts were used to augment major acetabular deficiencies and have been followed for a minimum of 24 months with a mean of 34 and a maximum follow-up period of 55 months. The autograft augmentations were uniformly successful. Two fixation failures occurred in the allograft group. Considering the extreme deficiency in the acetabulae encountered and the absence of sufficient autograft material in this group of patients, the use of frozen allografts (although less successful in this series) seems justified. Graft resorption as determined by direct roentgenographic measurements was less than might be expected but may be a manifestation of the short-term follow-up period. Resorption, however, was greater in the allograft group and, when marked, was associated with fixation failure.

Acetabulum↗

Cement composite delivery system.

Several new and innovative techniques have recently been introduced that purport to increase the strength of polymethyl methacrylate bone cement. One of these concepts is the use of carbon and polymer fibers to form a cement composite. Bone cement composites usually 1% fiber, are very difficult to use clinically. The composite is very sticky and viscous, which precludes effective hand packing or the use of conventional delivery systems. A new delivery system for very viscous materials is presented and examples of in vitro application are shown.

Animals↗

Metal allergy, metal implants and fracture healing.

The rabbit tibia was used as a model to study the effects of metal sensitivity reactions on the healing of fractures. Animals were injected with nickel chloride in Freund's complete adjuvant to cause sensitivity, and fractures were stabilized with 316L stainless steel intramedullary rods and followed for 16 weeks. A control group received no injections. The response was evaluated biomechanically with torsional testing at sacrifice, radiologically by examining the roentgenograms for evidence of loosening, and histologically. The results demonstrated a slight decrease in strength, a moderate increase in resorption and a significant decrease in cellularity and new bone formation in the sensitive animals as compared to control. These results are consistent with a reaction of comparatively short duration.

Animals↗