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Biomedical subjects

S Cotoi

Publications and source records attributed to S Cotoi.

At least 19 recordsLinked to original sources

Analysis of human atrial fibrillatory waves using monophasic action potential technique.

In 29 patients with atrial fibrillation, using the monophasic action potential technique, the fibrillatory waves were recorded and analyzed by statistical methods. Concerning the characteristics of the fibrillatory waves there are no differences between patients with rheumatic heart disease and with coronary heart disease. The patients with paroxysmal forms and those without heart failure and with normal heart size, have similar statistical data with regard to their fibrillatory waves. From the data presented, it could be possible to predict the efficacy of conversion to sinus rhythm and also the sinus rhythm stability after conversion.

Action Potentials

Two varieties of the onset of atrial fibrillation studied by monophasic action potential recording.

Two types of the initiation of atrial fibrillation are demonstrated in the continuous recordings of right atrial monophasic action potentials. In the first way, more common, atrial fibrillation takes place suddenly after an an extrasystolic atrial beat, in the second one it develops gradually after atrial tachycardia. In the first type the micro reentry starts from the beginning, in the second type only after sustained focal atrial tachycardia.

Action Potentials

[Increased atrial refractoriness: an explanation for the rarity of atrial arrhythmias in chronic cor pulmonale (author's transl)].

Right atrial monophasic action potential was recorded using a suction electrode catheter in 20 patients with chronic cor pulmonale. The duration of right atrial monophasic action potential was recorded using suction electrode catheter in 20 patients with chronic corpulmonale. The duration of right atrial monophasic action potential was 397 +/- 17 msec, longer than the normal value of 325 +/- 37 msec found in 30 normal subjects. The conclusion of our work is that the long right atrial monophasic action potential duration may explain the sinus rhythm stability and the rarity of atrial arrhythmias in chronic cor pulmonale.

Action Potentials

[Effects of lidocaine on supraventricular arrhythmias (author's transl)].

Using Lidocaine intravenously in 99 patients with atrial arrhythmias, it was observed that the drug has a regularising effect in 41 from 45 atrial arrhythmia, atrial tachycardia with block and accelerated ectopic supraventricular tachycardia, where the enhanced focal activity should be taken into account. No effect was observed in functional supraventricular tachycardia, paroxysmal atrial flutter and fibrillation and tachyarrhythmia in WPW syndrome, where the re-entry mechanism plays the major role. The effect of the drug is short lived, but may be prolonged by using the drug in perfusion or repeatedly with an intramuscular method. Lidocaine acts by depressing the enhanced atrial focal activity, and therefore may be of value in the treatment of these kinds of arrhythmias.

Adolescent

Double atrial parasystole. Case report.

A 62 year-old man with hiatal hernia and complex atrial arrhythmia is reported. On the standard electrocardiogram a double atrial parasystole is found, with reversed coupling. During carotid sinus massage only one of the parasystolic foci is not influenced, and assumes the atrial activity, regularizing the cardiac rhythm.

Arrhythmias, Cardiac

Complex atrial arrhythmias studied by suction electrode technique.

Two elderly patients with coronary heart disease, chronic pulmonary disease, and complex atrial arrhythmias are presented. The suction electrode technique for right atrium monophasic action potential recording was used. This recording allows better analysis of the atrial arrhythmias and estimates the stability of focal activity.

Action Potentials