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Biomedical subjects

S Conquy

Publications and source records attributed to S Conquy.

47 records · Page 3Linked to original sources

[Anticholinergics and urination disorders].

A urodynamic assessment with an anticholinergic test has been performed on 145 patients suffering of urge incontinence or micturition frequency. Eighty per cent had a detrusor instability and in those the test has shown to be positive in three half of the cases. In this group there was also an improvement with the oral treatment. In the others groups, the anticholinergic per os was almost never usefull. Anticholinergic drugs (not always well tolerated) are usefull when there is an instability and when the test is positive but not in the other cases.

Administration, Oral↗

[Urodynamic study of urinary incontinence following prostatic adenomectomy].

The urodynamic study of 31 patients suffering from urinary incontinence after prostatic adenomectomy showed us that there were 3 groups of patients very different in terms of symptoms and treatment: some had a low flow rate with an obstructive syndrome necessitating the treatment of the "obstacle"; others had a low flow rate and poor detrusor contraction and the last group had a high flow rate. Those two groups often need an artificial sphincter. The study is being continued in order to define a preoperative criterion of the risk of incontinence.

Adult↗

[Primary polyuria in the female. Classification and evolution].

51 adult female patients with unexplained urinary frequency underwent urodynamic assessment and were followed for at least six months. Half of these patients present with unstable bladder which could not be diagnosed clinically, even retrospectively. In 14 out of 16 cases, the instability resolved with an I.V. injection of an anticholinergic drug. The same treatment administered orally "cured" one half of the patients. This proportion was increased to 5 out of 6 when the drug was administered to patients with a positive I.V. test. Symptoms recurred once treatment was stopped. Ten of the 23 patients with a stable bladder improved spontaneously; anticholinergic drugs, when tried, appeared to have no effect. These results demonstrate the importance of diagnosing bladder instability in patients suffering from frequency and urgency.

Adult↗

[Cancer of the colon following ureterosigmoidostomy or following bladder enlargement using a colonic graft].

The role of carcinogenic factors following urinary diversion are here studied on the basis of three very different cases. In the first, an adenocarcinoma developed at the site of a ureterocolic anastomosis thirty one years after Coffey's operation for bladder exstrophy. In the second, the tumor had developed, 31 years after uretero-sigmoidostomy, for ureteral trauma. The anastomosis had moreover ceased to function ten years previously. In the third case, the patient had undergone a right nephrectomy for urinary tuberculosis and a colocystoplasty to enlarge the bladder with re-implantation of the left ureter in the graft. Twenty one years later, an adenocarcinoma developed at the site of the anastomosis between the colonic graft and the bladder. This was an exceptional case (possibly the first) of a cryptal tumor developing out of contact with material. It thus runs counter to the alleged role of facies in the development of adenocarcinomas following urinary diversion.

Adenocarcinoma↗

[Advances in surgical techniques and results of radical cystectomies for bladder cancer. 106 patients].

AIM OF THE STUDY: Retrospective analysis of result of radical cystectomy at Cochin Hospital. PATIENTS AND METHODS: We report the results of a 106 patients series treated by radical cystectomy for bladder carcinoma after a 5-year period follow-up. RESULTS: The extent of the tumour invasion according to pathological analysis was: pT1 or less: 26%, pT2 and pT3a: 33%, pT3b and over: 41%. Morbidity rate was 19% with a 7.5% reintervention rate. Long term complication rate was 31%, concerning essentially ureteral stenosis. A local recurrence or distant metastasis occurred in 35% of patients. Local recurrence rate was 10.7%. Cancer specific survival rates were 88%, 81% and 42% for pT1, pT2-pT3a, and pT3b patients respectively. CONCLUSION: The present results confirm that radical cystectomy is the most effective curative treatment for invasive bladder carcinoma.

Adult↗

[Treatment in men].

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Collagen↗