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Biomedical subjects

S Cimino

Publications and source records attributed to S Cimino.

5 recordsLinked to original sources

[Primary hyperoxaluria and pregnancy].

A rare case of pregnancy in a patient with primary hyperoxaluria type 1 is reported offering a clinical contribution for the prognostic study of a natural event such as the pregnancy on these patients. It is underlined how epicriticity of the hepatorenal system is remarkably altered during the last weeks of pregnancy with a great increase of calciuria and proteinuria with a risk of life for the patient and the newborn. In fact, during the 36rd week a caesarean section was performed due to gestosis. Moreover, the deterioration of kidney functionality doesn't decrease during post partum. Therefore, it would be advisable inform these patients about the risk of pregnancy.

Adult↗

Feeding disorders in infancy: an empirical study on mother-infant interactions.

AIM: The objective of this paper is an empirical analysis of mother-infant feeding interactions through an observational instrument (Feeding Scale), which is applied to the videotape of a feeding session. METHODS: Three samples of mothers and their children have been examined (104 couples with children ranging in age from 2 to 36 months: a first group in which children presented a feeding disorder on organic and functional base (food intolerances and/or gastroesophageal reflux), a second group in which the disorder was not due to a medical condition and a third group of control. The Authors meant to test three hypotheses: 1) the presence of developmental changes in mother-infant interactional patterns during the course of the first three years of life; 2) higher degree of dysfunction of mother-infant interaction in those dyads in which the feeding disorder had not organic causes; 3) dysfunctional interactions in the couples of mothers and children in which the feeding disorder was on an organic base. RESULTS: The results of the statistic analyses have confirmed the hypotheses, providing different elements of reflection. CONCLUSIONS: The Authors underline the importance of a multidimensional, global and integrated approach in the clinical assessment and treatment, which evaluates the possible interconnections among organic, psychogenetic and relational factors in the origin and course of feeding disorders in infancy and early childhood.

Adult↗

[Early kidney-pancreas transplantation in type 1 diabetics prevents hemodialysis].

BACKGROUND: The life-expectancy of type 1 diabetics (T1D) on dialysis is still shorter than that of non-diabetics. Pancreas transplantation (PT) in its different modalities should be considered as a life-saving procedure. METHODS: We analyzed our referral activity of T1D to PT from 1992. Since 2002, we have created a kidney and diabetes out-patient clinic devoted to the prevention of diabetic nephropathy and to the early referral of suitable T1D to combined kidney- pancreas transplantation (KPT) and isolated pancreas (PTA). RESULTS: In the last 14 yrs, 25 T1D underwent KP in our district (620000 inhabitants). At the beginning, KPT was performed abroad, but then the borders were closed. After stopping in the mid 1990s, KP activity restarted addressing preemptive KPT and PTA. Currently, only one patient is on dialysis while awaiting KPT. Four T1D were evaluated and excluded from the list on medical grounds; two patients are on the list and a further two patients are currently under evaluation. CONCLUSIONS: The implementation of a cooperative network among dialysis and transplant centers, supported by devoted out-patient clinics allowed the effective prevention of the dialysis requirement in T1D. Out-patient clinics devoted to diabetic nephropathy should play a pro-active role in preemptive KP, including the 'new' option of islet transplantation according to the Edmonton protocol.

Diabetes Mellitus, Type 1↗