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Biomedical subjects

S Cassin

Publications and source records attributed to S Cassin.

78 records · Page 5Linked to original sources
PubMedDate not supplied

Young injectors: a comparative analysis of risk behaviour.

This study compares the injecting and sexual risk-behaviour of young injectors, with injectors over the age of 25. All respondents presented for the first time at the Merchants' Quay Health Promotion Unit between May 1st 1997 and February 28th 1998. Analysis revealed that the young injectors were significantly more likely to report recently borrowing and lending used injecting equipment, and injecting paraphernalia. Regarding sexual risk behaviour, younger respondents were proportionately more likely to report being sexually active, having multiple sexual partners, and having a regular partner who is an injecting drug user. However, they were significantly more likely than older clients to report condom use. The suggestion is that the harm minimisation message, which reached its zenith in the early 1990s, has now been somewhat de-emphasised in both policy and practice. Consequently, it is not reaching the young injectors who have recently initiated intravenous drug use. Additional strategies are needed this group of drug users, in order to promote positive behaviour changes.

Adolescent↗
PubMedDate not supplied

The role of eicosanoids and endothelium-dependent factors in regulation of the fetal pulmonary circulation.

A complex interaction of mechanical, hormonal, vasoactive, morphological and gaseous factors is responsible for the transitional period and maintenance of these changes in the newborn period. Vasoactive eicosanoids, formed at multiple sites in the lungs exert multiple effects on the perinatal pulmonary circulation. By direct, as well as indirect interaction with other systems, eicosanoids appear to have a role in the rearrangement of the circulation at birth. At this time PGE1, acetylcholine, bradykinin, and endothelin appears to work, at least in part, to cause fetal pulmonary vasodilation via the release of EDRF. Products of the lipoxygenase pathway are powerful vasoconstrictors, but may not be important in regulation of high fetal pulmonary vascular tone or the pulmonary pressor response to hypoxia.

Animals↗