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Biomedical subjects

S Carlsson

Publications and source records attributed to S Carlsson.

At least 109 records · Page 6Linked to original sources
PubMed1978

The myocardial capillary vasculature in repeated physical exercise. An experimental investigation in the rat.

The neoformation of myocardial blood capillaries was investigated on cardiac autoradiograms from 3H-thymidine injected rats that had been swimming-exercised for two weeks, rats that had been resting for three months following the exercise, and rats in which the rest had been followed by a second two-weeks period of exercise. The initial period of exercise induced a signficant capillary neoformation in the hearts. The newly-formed vasculature was found of functional significance still at the end of the resting period and available for the increased demands on the myocardial vasculature when the exercise was resumed.

Animals↗
PubMed1978

The reaction of the vascular pattern of the hypertrophied myocardium to increased cardiac volume load. A microangiographical study.

Myocardial stereo-microangiography was performed on 30 rats after swimming exercise for one or two periods with and without a previous operation for production of aortic stenosis. In 8 rats with aortic stenosis no swimming exercise followed, and 10 more rats served as normal controls. Swimming exercise resulted in a higher degree of cardiac hypertrophy than aortic stenosis. Both types of cardiac hypertrophy resulted in vascular adaptive reactions in the myocardium. The adaptive reaction to swimming exercise was found to be persistent, at least to some extent, and to be of use if the exercise was resumed. The adaptive alterations in aortic stenosis were further modified by a superimposed period of exercise, although the nutritive capillary vasculature only showed a slight and focal increase in density.

Animals↗
PubMed1976

The myocardial capillary vasculature in exercising animals with increased cardiac pressure load.

The myocardial capillary reaction was studied in normal rats subjected to swimming exercise and in rats in which aortic stenosis had been produced at various time intervals before the swimming exercise was commenced. The data obtained indicated that neoformation of myocardial capillaries during swimming exercise occurred only in rats without aortic stenosis. It is concluded that a heart subjected to an increased pressure load is less able to respond to a superimposed volume load by an increase in its capillary supply than is a normal heart.

Animals↗
PubMed1976

Autonomous hyperparathyroidism: a possible late complication of neck radiotherapy.

In a series of 170 patients operated on for autonomous hyperparathyroidism (HPT) during a four-year period ending 1974, 24 patients (14%) had, earlier in life, received radiation therapy to the neck region for various benign conditions. Treatment records were traced in 19 cases. The estimates of absorbed dose in the parathyroids ranged from 200 to 3 000 rad. Eighteen patients had their first course of treatment in childhood or early adult life. The diagnosis of HPT was established in these patients 42 years (average) after exposure to radiation. Six patients who were irradiated after the age of 48 had an average time lapse of 12 years before the diagnosis of HPT was made. The occurrence of signs and symptoms related to HPT was similar in exposed and non-exposed patients. The high incidence of previous neck radiotherapy in our series suggests that radiation may be a contributory factor in the development of HPT.

Adult↗