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Biomedical subjects

S Canonico

Publications and source records attributed to S Canonico.

31 records · Page 2Linked to original sources
PubMed1990

Evaluation of normal subjects by defecographic technique.

A simple method of defecation radiography using video recording of evacuation of a suspension of radiopaque barium sulfate in ten normal volunteers to establish physiologic parameters is described. Clinical perineal descent and defecographic measurement have been performed. The anorectal angle (ARA) was, on the average, 90.00 +/- 4.76 degrees (SEM) at rest and 111.00 +/- 5.02 degrees (SEM) during evacuation. The width of the anal canal (W) was, on the average, 1.29 +/- 0.13 cm (SEM). The duration of sphincteric relaxation (SRT) was, on the average, 4.50 +/- 1.04 sec (SEM), with a total average evacuation time (TET) of 12.00 +/- 3.54 sec (SEM). The authors confirm the effectiveness of defecographic techniques and recommend the standardization of the method to have an unequivocal interpretation of the obtained data.

Adult↗
PubMed1989

[Surgical anatomy of the rectum: technical notes].

To have a good knowledge of pelvic and rectal areas is very important to avoid major complications of the rectal surgery. Important technical points are: posterior dissection in the pre-sacral space: this space can be easily demonstrated performing the separation immediately behind the superior rectal artery and then cutting the recto-sacral fascia. This is the correct procedure to avoid dangerous bleedings too; total dissection of the mesorectum for neoplastic disease; it is possible to apply this technique for benign diseases too with a minimal bleeding and without an increase of lesions of the nervous plexes; lateral dissection, that follows the posterior dissection, is performed very close to the pelvic wall for neoplastic diseases and very close to the rectum for benign diseases; anterior dissection, that is performed before the Denonvillier's fascia for neoplastic diseases and behind it for benign diseases.

Dissection↗
PubMedDate not supplied

[Blood coagulation changes in patients with post-splenectomy persistent thrombocytosis].

To clarify the possible role of persistent thrombocytosis after splenectomy as being a predisposing factor causing thromboembolism. Blood coagulation profiles were studied in 35 patients (20 M and 15 F, mean age 42 +/- 17.5) suffering from thrombocytosis (> 500,000/dl) who underwent splenectomy for non-malignant and non-traumatic diseases. Seventy healthy subjects acted as a control group. Tests were performed 6 months after the operation and for both groups (patients and controls) blood samples were collected for: platelets, fibrinogen, PT, APTT, AT III, plasminogen, F1 + 2, t-PA and DNA analysis for F V, F II and MTHFR. After one year all subjects were controlled for thrombocytosis, genomic abnormalities and venous thrombosis. All the analyses were performed according to the Statistical Package for Social Science. The significance of the differences in means was evaluated by non-parametric tests, differences with a P value < 0.05 being considered significant. Increased plasma levels of fibrinogen, D-dimer, F1 + 2 and PAI-1 were found in the patients compared with the control group. TPA was significantly lower in the patients than in the controls. At the one year follow-up, two patients with genetic polymorphism had suffered deep venous thrombosis. Our findings indicate that splenectomy contributes to abnormal platelet aggregation and endothelial cell activation with hypercoagulability.

Adult↗