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Biomedical subjects

S C Shih

Publications and source records attributed to S C Shih.

At least 37 records · Page 2Linked to original sources
PubMed1993

[Seasonal variation of peptic ulcer hemorrhage].

Retrospectively analysis of 2015 episodes of duodenal ulcer (DU) hemorrhage, and 874 episodes of gastric ulcer (GU) hemorrhage over a 5-year period (April, 1987-March, 1992) evaluated seasonal incidence. For duodenal ulcers, the highest incidence occurred in January, or a total of 231 episodes over 5 years (4.6% of all medical admission), whereas the lowest incidence was in August, with only 101 episodes in the same period (2.1% of medical admission). There was a statistically greater incidence of DU bleeding during the relatively cool winter months, December to March (835 episodes, 4.3%) vs. the warmer summer months, June to September (500 episodes, 2.5%; p < 0.05). For gastric ulcers, the incidence of bleeding was highest in January and February (1.9%) and lowest in September (1.1%). As with DU, GU bleeding was more common in winter (332 episodes, 1.7%) than in summer (243 episodes, 1.2%; p < 0.05). Over one year of this series (DU bleeds: 390, GU bleeds: 167), there was no predilection for a particular day of the week. Of patients evaluated in that year, 87 with DU and 17 with GU had history of bleeding at least one time before. However, there was no seasonal correlation with the previous bleeding episodes. It was concluded that there is seasonal variation in the incidence of peptic ulcer hemorrhage in our country. However, it is not possible to predict when in the year patients are likely to rebleed.

Adolescent↗
PubMed1992

[Clinical analysis of adenocarcinoma of the stomach in patients with duodenal ulcer].

In 332 patients of adenocarcinoma of the stomach and 7095 patients with duodenal ulcer collected in 5-year period, 21 cases were found to have both disease entities. With regard to clinical manifestations, gross morphology, microscopic differentiation and management of adenocarcinoma of the stomach, the patients with duodenal ulcer showed no significant difference from those without duodenal ulcer. The activities of the duodenal ulcers could be in acute active stage or present as chronic scar only. The ulcer history varied from several years to more than 15 years. We concluded that the frequency of adenocarcinoma of the stomach developed in patients with duodenal ulcer is not so rare, presentation of epigastric discomfort or signs of UGI bleeding in patients with duodenal ulcer history not always indicated recurrence of ulcer disease.

Adenocarcinoma↗
PubMed1989

Secondary biliary cirrhosis. A limiting factor in the treatment of hepatolithiasis.

To investigate whether the coexistence of secondary biliary cirrhosis plays a limiting role in the treatment of hepatolithiasis, we retrospectively compared the clinical course and results of stone treatment in 30 patients with secondary biliary cirrhosis (8 in Child's class A and 22 in Child's class B) (group 1) and 240 patients with noncirrhotic biliary calculi (group 2). The hospital mortality, morbidity of treatment, mortality of treatment, and the percentage of treatment failure in group 1 were 20%, 40%, 6.7%, and 16.7%, respectively. Those in group 2 were 8%, 10%, 3.8%, and 10%, respectively. The modes of treatment for stone removal included surgery with postoperative cholangioscopy and percutaneous transhepatic cholangioscopy. There was a statistically significant difference between these two groups in the hospital mortality and the morbidity of treatment. We conclude that hepatolithiasis and biliary stricture should be treated early, before the development of secondary biliary cirrhosis. However, even after cirrhosis occurs, aggressive treatment does not increase the mortality of treatment or the treatment failure rate.

Adult↗
PubMed1980

Screening for barley mutants with altered hormone sensitivity in their aleurone layers.

A method, based on the diffusion assay of alpha-amylase on agar plates, was developed to screen for barley (Himalaya) mutants with altered sensitivity to gibberellic acid (GA(3)) or abscisic acid (ABA) in their aleurone layers. The seeds produced by sodium azide-mutagenized barley were screened for their ability to synthesize and secrete alpha-amylase when treated with different combinations of hormones. Various GA(3)-insensitive or supersensitive, ABA-insensitive, temperature-dependent GA(3)-insensitive, and constitutive mutants have been identified. Several stable mutants with altered GA(3) sensitivity were recovered. Two of the homozygous GA(3)-insensitive mutants have been preliminarily characterized. The GA(3)-enhanced production of alpha-amylase and release of phosphatase are hampered in these mutants. However, they have normal stem height, and the uptake of GA(3) by their aleurone layers appears to be the same as that of wild-type barley. They are most likely regulatory mutants affecting both alpha-amylase synthesis and phosphatase release.

Journal Article↗
PubMed1976

Extractant Influence on the Relationship between Extractable Proteins and Cold Tolerance of Alfalfa.

The influence of ionic composition and pH of extractant on the relationship between the extracted proteins and the cold tolerance of Vernal and Arizona Common alfalfa (Medicago sativa L.) was examined. Five environments were used to induce different tolerance levels. The quantity of protein extracted from plants was influenced by the hardening environment, cultivar, and ionic composition and pH of 29 extractants. Extractants with a pH below 6 generally extracted less protein.The measured cold tolerance of the plants was correlated with the quantity of protein detected in many of the 14 regions of the electrophoresis gel columns regardless of extractant but was most closely associated with the protein in either region 7 or 8 with nine of ten extractants.The magnitudes of cultivar and hardening effects on quantities of protein detected on various column regions were influenced by choice of extractant. This suggests that proper extractant selection may be vital for study of isozymes by electrophoresis.

Journal Article↗
PubMed1967

Influence of Purines and Pyrimidines on Cold Hardiness of Plants. III. Associated Changes in Soluble Protein and Nucleic Acid Content and Tissue pH.

When applications of certain purines and pyrimidines enhanced the development or maintenance of cold hardiness, the content of water-soluble, trichloroacetic acid-precipitable protein and nucleic acids and tissue pH were higher in treated plants than in controls. The reverse was generally true when the treated plants were less cold hardy than the controls. In some instances, the purines and pyrimidines increased the content of these nitrogenous constituents in a nonhardy variety to a level equal to that found in untreated plants of a hardy variety.

Journal Article↗
PubMedDate not supplied

Limitations of percutaneous transhepatic cholangioscopy in the removal of complicated biliary calculi.

To investigate the limitations of percutaneous transhepatic cholangioscopic lithotomy (PTCSL) in the management of retained or reformed biliary calculi, we conducted a retrospective study of 50 patients who had received PTCSL for complicated biliary calculi during a period of 32 months. The calculi were located in the common bile duct (24%), the intrahepatic bile ducts (60%), and in both the common bile duct and intrahepatic bile ducts (16%). The adjunctive techniques in PTCSL included balloon dilatation for the biliary stricture, electrohydraulic lithotripsy (EHL) for crushing large impacted stones, and flushing techniques, biliary spoons, and basket catheters for stone fragmentation and grasping. The overall percutaneous manipulations totaled 221 procedures, including 124 sessions of PTCS. In each patient, the number of sessions of PTCS varied from 1 to 7. In our series, the main complications of PTCS therapy, rarely reported in the literature, included pain intolerance in 7 cases (14%), minor bleeding in 7 cases (14%), and massive bleeding which needed angiographic diagnosis and therapy for hemostasis in 5 cases (10%). Secondary biliary cirrhosis, severe biliary stricture and angulations, previous shunt surgery, neovascularization surrounding the chronic inflammatory stenotic intrahepatic bile ducts, pseudoaneurysm formation, and coexistent cholangiocarcinoma contributed to the vulnerability of bleeding during manipulations. The complications resulted in treatment failure in 11 patients (22%). We conclude that PTCS is a useful alternative treatment to surgery for biliary calculi, but it has limitations that obviate complete stone clearance.

Adult↗