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Biomedical subjects

S C Sharma

Publications and source records attributed to S C Sharma.

At least 253 records · Page 14Linked to original sources
PubMed1984

Comparison of blood levels of histamine and total ascorbic acid in pre-eclampsia with normal pregnancy.

Levels of histamine and total ascorbic acid (L-ascorbic acid plus dehydroascorbic acid) in the peripheral blood of women in pre-eclampsia have been measured. The results show that blood histamine is increased both in the moderate and severe form of pre-eclampsia. Blood ascorbic acid on the other hand is increased only in the severe form of pre-eclampsia. The rise in histamine values may be in response to the rising blood pressure in pre-eclampsia. The rise in ascorbic acid values may reflect the reduced maternal blood volume and/or restricted transport of ascorbic acid from maternal to fetal tissues.

Adult↗
PubMed1983

The ipsilateral retinotectal projection in normal and albino channel catfish.

The retinal projection to the ipsilateral optic tectum was examined first in normal channel catfish. After unilateral optic nerve section and horseradish peroxidase (HRP) application, a sparse retinal projection was seen in the ipsilateral optic tectum. When HRP was applied to the ipsilateral rostral tectum, labeled ganglion cells were observed in the ventrotemporal quadrant of the ipsilateral eye. Electrophysiological mapping of the ipsilateral projection confirmed that cells in the temporal retina projected to the rostral tectum. When albino catfish were examined using these techniques, the ipsilateral retinotectal projection was found to be much sparser than the ipsilateral projection of normal catfish.

Albinism↗
PubMed1983

Computed tomography and radiotherapy in the treatment of cancer.

Computed tomography (CT) has shown to be of great value in the treatment of cancer with radiation therapy. It is used more and more in the estimation of tumor volume and for treatment planning, with the aid of the computerized treatment unit. At the James Graham Brown Cancer Center, Department of Radiation Oncology, CT has been used routinely for the treatment planning. From October 1, 1981 to June 30, 1982, we performed 180 CT scans for the treatment planning, 380 simple dose calculations, 237 complex treatment plans, and 42 intracavitary dosimetry using the treatment planning unit. This is a review of our experience with some illustrations. Accurate tumor dose can be delivered with reducing the complications with the use of CT and the computerized treatment unit.

Brachytherapy↗
PubMed1983

Hemodynamic, biochemical and morphological changes in the dextran and D-galactosamine-induced edemas in rats.

Dextran (600 mg/kg i.p.) and D-galactosamine (300 mg/kg s.c.)-induced edemas in the rat have been evaluated and compared on the basis of hemodynamic, biochemical and morphological investigations. The genesis of the edema induced by dextran was quicker (1-3 hr) than that induced by D-galactosamine. The edema index at the levels of the paws was higher in the dextran (10.5 +/- 0.6) than in the D-galactosamine (5.1 +/- 0.4)-induced edema. Furthermore, the dextran-induced edema was associated with marked hypotension and a decrease in the plasma protein levels. Bradycardia, decrease in the cardiac output and the coronary blood flow were observed in both the edemas. Blood flows to the brain, kidneys, lungs, spleen and paws were decreased only in the dextran-induced edema. It was interesting to note that the percentage distribution of the cardiac output in the paws was decreased in the dextran-induced edema only. PGE2 levels were increased, whereas the histamine levels were decreased in the paw-skin in both the edemas. These changes were relatively more marked in the dextran edema. The levels of PGF2 alpha remained unchanged. The above findings have been further supported by our morphological data where relatively more degranulation of the mast cells and that too at a shorter period, was observed in the dextran-induced edema. Different mechanisms for the genesis of these two kinds of edemas have been suggested.

Animals↗
PubMed1983

Treatment of arsenical keratosis with etretinate.

Treatment with oral etretinate is reported in a case of arsenical keratosis with Bowen's disease. Good (80%) clearance in keratoses was obtained, which is maintained after 15 months' follow up.

Administration, Oral↗